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News at a glance: New gene therapy, Europe ’s drought, and a black hole’s photon ring
ARCHAEOLOGY Drought exposes ‘Spanish Stonehenge’ for study Scientists are rushing to examine a 7000-year-old stone circle in central Spain that had been drowned by a reservoir for decades and was uncovered after the drought plaguing Europe lowered water levels. Nicknamed the “Spanish Stonehenge”—although 2000 years older than the U.K. stone circle—the Dolmen of Guadalperal (above) was described by archaeologists in the 1920s. The approximately 100 standing stones, up to 1.8 meters tall and arranged around an oval open space, were submerged in the Valdecañas reservoir after the construction of a ...
Source: Science of Aging Knowledge Environment - August 25, 2022 Category: Geriatrics Source Type: research

What Researchers Have Learned About Whether it ’s Possible to ‘Cure’ HIV
It’s the news that the HIV community has been waiting four long decades for: the hint that maybe, just maybe, HIV can be cured. Dr. Xu Yu, a principal investigator at the Ragon Institute of Massachusetts General Hospital, MIT and Harvard, as well as an associate professor of medicine at Harvard Medical School, had to check and recheck her results to be sure. In one of her patients, test after test to detect evidence of HIV in the woman’s blood came up empty. In addition to her lab’s results, “We had complementary assays in labs in Australia, D.C. and Argentina, where the patient is from, all trying ...
Source: TIME: Health - November 30, 2021 Category: Consumer Health News Authors: Alice Park Tags: Uncategorized healthscienceclimate HIV/AIDS Source Type: news

Covid fightback: the critical role of HIV experts
The speed and cooperation of the Covid response has been honed by decades of dealing with ‘the biggest pandemic the world has ever seen’When Dr Anthony Fauci spoke at the 20th International Aids Conference in Melbourne in 2014, his appearance garnered little media attention.Nearly seven years later, theHIV expert and director of the US National Institute of Allergy and Infectious Diseases has become a household name throughout the world as the adviser to the White House on theCovid-19 pandemic, appearing in the media daily and speaking plainly about the science and the nature of the virus.Continue reading...
Source: Guardian Unlimited Science - March 5, 2021 Category: Science Authors: Melissa Davey Tags: Health Coronavirus Aids and HIV Australia news Medical research Vaccines and immunisation Infectious diseases Science Source Type: news

Leukocyte Heparanase: A Double-Edged Sword in Tumor Progression
Conclusions This review describes how leukocyte-heparanase can be a double-edged sword in tumor progression; it can enhance tumor immune surveillance and tumor cell clearance, but also promote tumor survival and growth. We also discuss the potential of using heparanase in leukocyte therapies against tumors, and the effects of heparanase inhibitors on tumor progression and immunity. We are just beginning to understand the influence of heparanase on a pro/anti-tumor immune response, and there are still many questions to answer. How do the pro/anti-tumorigenic effects of heparanase differ across different cancer types? Does...
Source: Frontiers in Oncology - April 29, 2019 Category: Cancer & Oncology Source Type: research

National Hand Hygiene Initiative Successful in Australia
Overall hand hygiene compliance increased from 2009 to 2017; associated drop seen in HA - SAB incidence
Source: The Doctors Lounge - Psychiatry - April 19, 2019 Category: Psychiatry Tags: Cardiology, Dermatology, Endocrinology, Family Medicine, Geriatrics, Gastroenterology, Gynecology, Infections, AIDS, Internal Medicine, Allergy, Critical Care, Emergency Medicine, Nephrology, Neurology, Nursing, Oncology, Ophthalmology, Orthopedics, ENT, Source Type: news

Case Study: Mechanism for Increased Follicular Helper T Cell Development in Activated PI3K Delta Syndrome
This study was carried out after written informed consent from all subjects. All subjects gave written informed consent in accordance with the Declaration of Helsinki. The protocol was approved by the Stanford University and UCLA Institutional Review Boards. Author Contributions MB provided patient care and obtained IRB approval. RO prepared histology images. MB, TT, and RB designed the research. TT and LP conducted experiments and analyzed data. MB made the molecular model. MB and TT wrote the manuscript. Funding Funding for this work came from the Jeffrey Modell Foundation and from the NIH/NIGMS (R01 GM110482 to MB)....
Source: Frontiers in Immunology - April 11, 2019 Category: Allergy & Immunology Source Type: research