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Specialty: Cardiology
Condition: Disability

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Total 417 results found since Jan 2013.

Exercise for the Prevention of Anthracycline-induced Functional Disability and Cardiac Dysfunction: The BReast Cancer Randomized EXercise InTervention (BREXIT) Study
Conclusions: In women with early-stage BC undergoing AC, 12-months of ExT did not attenuate functional disability but provided large and clinically meaningful benefits on VO2peak and cardiac reserve. Clinical Trial Registration: URL: https://www.anzctr.org.au/ Unique Identifier: ACTRN12617001408370.PMID:36342348 | DOI:10.1161/CIRCULATIONAHA.122.062814
Source: Circulation - November 7, 2022 Category: Cardiology Authors: Stephen J Foulkes Erin J Howden Mark J Haykowsky Yoland Antill Agus Salim Sophie S Nightingale Sherene Loi Piet Claus Kristel Janssens Amy M Mitchell Leah Wright Ben T Costello Anniina Lindqvist Lauren Burnham Imogen Wallace Robin M Daly Steve F Fraser An Source Type: research

Carotid atherosclerotic disease: A systematic review of pathogenesis and management
Brain Circ. 2022 Sep 21;8(3):127-136. doi: 10.4103/bc.bc_36_22. eCollection 2022 Jul-Sep.ABSTRACTCarotid stenosis is an important contributor to ischemic stroke risk with resultant significant impact on neurological disability and death in adults and with worldwide implications. Management of carotid stenosis is impacted by whether there are associated symptoms along with the degree of stenosis. Understanding of the pathogenesis of carotid atherosclerosis or stenosis is important in management of carotid stenosis. Atherosclerotic plaque formation is a chronic insidious process with a number of potential contributors to the...
Source: Atherosclerosis - October 21, 2022 Category: Cardiology Authors: Shyamal C Bir Roger E Kelley Source Type: research

Prediction of long-term outcomes by arterial stiffness and pressure wave reflections in patients with acute stroke: the Athens Stroke Registry
Background and purpose: Stroke patients’ management might be improved by addressing the role of aortic stiffness (carotid-femoral pulse wave velocity: cfPWV) and pressure wave reflections (PWRs, augmentation index: AIx) in their pathogenesis and outcome. We tested the hypothesis that cfPWV and AIx, separately and combined, predict long-term outcomes [all-cause mortality, incidence of cardiovascular events, stroke recurrence and disability defined by modified Ranking Scale (mRS) ≥3] in patients with acute stroke, using data from the ‘Athens Stroke Registry’. Methods: Data from 552 patients (70% men, age: ...
Source: Journal of Hypertension - October 18, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

The role of blood pressure management in stroke prevention: current status and future prospects
Expert Rev Cardiovasc Ther. 2022 Oct 16. doi: 10.1080/14779072.2022.2137490. Online ahead of print.ABSTRACTINTRODUCTION: Stroke is the second-leading cause of death worldwide and the second-leading cause of disability-adjusted life-years. It is well-known that hypertension is a significant risk factor for cardiovascular events, including stroke.AREAS COVERED: Recent interventional trials have demonstrated the superiority of intensive blood pressure (BP) control for prevention of cardiovascular events compared to standard BP control. Notably, in the Strategy of Blood Pressure Intervention in Elderly Hypertensive Patients (S...
Source: Expert Review of Cardiovascular Therapy - October 17, 2022 Category: Cardiology Authors: Keisuke Narita Satoshi Hoshide Kazuomi Kario Source Type: research

CircRNAs: Key molecules in the prevention and treatment of ischemic stroke
This article aims to provide new ideas about the pathogenesis and progression of ischemic stroke by reviewing the roles of circRNAs in cerebral ischemic injury and summarizing the association between circRNAs and risk factors for ischemic stroke.PMID:36244267 | DOI:10.1016/j.biopha.2022.113845
Source: Atherosclerosis - October 16, 2022 Category: Cardiology Authors: Zeyu Liu Yanhong Zhou Jian Xia Source Type: research

Outcomes of Mild Stroke and High-risk Transient Ischemic Attack in Current Clinical Practice
CONCLUSION: Implementation of the up-to-date standard care in clinical practice might bring good clinical outcomes to the patients with mild stroke and high-risk TIA.PMID:36130531 | DOI:10.1159/000526969
Source: Atherosclerosis - September 21, 2022 Category: Cardiology Authors: Apiluk Wesanonthawech Pornpatr A Dharmasaroja Source Type: research

Molecular mechanisms for the prevention and promoting the recovery from ischemic stroke by nutraceutical laminarin: A comparative transcriptomic approach
Front Nutr. 2022 Aug 24;9:999426. doi: 10.3389/fnut.2022.999426. eCollection 2022.ABSTRACTStroke is the second leading cause of death and a major cause of disability worldwide. Ischemic stroke caused by atherosclerosis accounts for approximately 87% of all stroke cases. Ischemic stroke is a preventable disease; therefore, a better understanding of the molecular mechanisms underlying its pathogenesis and recovery processes could provide therapeutic targets for drug development and reduce the associated mortality rate. Laminarin, a polysaccharide, is a nutraceutical that can be found in brown algae. Accumulating evidence sug...
Source: Atherosclerosis - September 19, 2022 Category: Cardiology Authors: Jiefeng Luo Dingzhi Chen Biyun Qin Deyan Kong Source Type: research

Evaluation of Mean Platelet Volume and Platelet Count in Ischemic stroke and its subtypes: Focus on degree of disability and thrombus formation
Conclusions: Elevated MPV is an independent risk factor for Ischemic stroke along with hypertension. In addition, higher MPV associated significantly with stroke disability as well.PMID:36028984 | DOI:10.1080/00207454.2022.2118599
Source: Atherosclerosis - August 27, 2022 Category: Cardiology Authors: Abhilash Ludhiadch Pooja Yadav Sunil Kumar Singh None Sulena Anjana Munshi Source Type: research

Stroke Disability Eased by Remote Ischemic Conditioning in Randomized Trial
(MedPage Today) -- Remote ischemic conditioning (RIC) finally showed a functional benefit in stroke when administered for 2 weeks among survivors, according to the RICAMIS trial. People with acute ischemic stroke randomized to the study's RIC...
Source: MedPage Today Cardiovascular - August 16, 2022 Category: Cardiology Source Type: news

The effectiveness of serum S100B, TRAIL, and adropin levels in predicting clinical outcome, final infarct core, and stroke subtypes of acute ischemic stroke patients
CONCLUSION: TRAIL and adropin serum levels were associated with poor clinical outcomes and greater infarcted area in acute ischemic stroke patients.PMID:35866730 | DOI:10.7705/biomedica.5943
Source: Atherosclerosis - July 22, 2022 Category: Cardiology Authors: Ozge Altintas Kadirhan Okkes Taha Kucukdagli Bedia Gulen Source Type: research

International Union of Angiology (IUA) consensus paper on imaging strategies in atherosclerotic carotid artery imaging: From basic strategies to advanced approaches
Atherosclerosis. 2022 Jun 28;354:23-40. doi: 10.1016/j.atherosclerosis.2022.06.1014. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is the leading cause of mortality and disability in developed countries. According to WHO, an estimated 17.9 million people died from CVDs in 2019, representing 32% of all global deaths. Of these deaths, 85% were due to major adverse cardiac and cerebral events. Early detection and care for individuals at high risk could save lives, alleviate suffering, and diminish economic burden associated with these diseases. Carotid artery disease is not only a well-established risk factor for...
Source: Atherosclerosis - July 11, 2022 Category: Cardiology Authors: Luca Saba Pier Luigi Antignani Ajay Gupta Riccardo Cau Kosmas I Paraskevas Pavel Poredos Bruce Wasserman Hooman Kamel Efthymios D Avgerinos Rodrigo Salgado Federico Caobelli Leonardo Aluigi Luis Savastano Martin Brown Tom Hatsukami Emad Hussein Jasjit S S Source Type: research