• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Icariin attenuates ischemic stroke through suppressing inflammation mediated by endoplasmic reticulum stress signaling pathway in rats
This article is protected by copyright. All rights reserved.PMID:35451526 | DOI:10.1111/1440-1681.13645
Source: Clinical and Experimental Pharmacology and Physiology - April 22, 2022 Category: Drugs & Pharmacology Authors: Jie Zheng Yuling Liao Yuanyuan Xu Zhentao Mo Source Type: research

Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin. Ethics Statement This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Clinical benefits and pharmacology of scutellarin: A comprehensive review
Publication date: Available online 6 May 2018Source: Pharmacology & TherapeuticsAuthor(s): Liping Wang, Qiang MaAbstractStroke and myocardial infarction are among the most common causes of mortality and disability in the world. The ischemic injury underlying these illnesses is complex, involving intricate interplays among many biological functions including energy metabolism, vascular regulation, hemodynamics, oxidative stress, inflammation, platelet activation, and tissue repair that take place in a context- and time-dependent manner. The current drug therapy of choice is to timely resupply the blood to the ischemic tissu...
Source: Pharmacology and Therapeutics - July 10, 2018 Category: Drugs & Pharmacology Source Type: research

Clinical benefits and pharmacology of Scutellarin: A comprehensive review
Publication date: Available online 6 May 2018 Source:Pharmacology & Therapeutics Author(s): Liping Wang, Qiang Ma Stroke and myocardial infarction are among the most common causes of mortality and disability in the world. The ischemic injury underlying these illnesses is complex, involving intricate interplays among many biological functions including energy metabolism, vascular regulation, hemodynamics, oxidative stress, inflammation, platelet activation, and tissue repair that take place in a context- and time-dependent manner. The current drug therapy of choice is to timely resupply the blood to the ischemic ti...
Source: Pharmacology and Therapeutics - May 6, 2018 Category: Drugs & Pharmacology Source Type: research

Pages: 1  2