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Oxidative stress and early mortality in acute ischemic stroke: A prospective cohort study
CONCLUSION: MDA serum level was significantly higher in non-survivors than in survivors patients, so MDA could be used as a predictor for early mortality and short-term outcome of cases with AIS.PMID:37652662 | DOI:10.1080/01616412.2023.2252284
Source: Neurological Research - August 31, 2023 Category: Neurology Authors: Eman A Elhamrawy Heba Shoman Hayam Abdel-Tawab Eshak I Bahbah Rasha Sobhy Elattar Naema R Hussein Marwa Sonbol Asmaa AbdElghany Elsheikh Source Type: research

Surgery for Malignant Acute Ischemic Stroke: A Narrative Review of the Knowns and Unknowns
Semin Neurol 2023; 43: 370-387 DOI: 10.1055/s-0043-1771208Malignant acute ischemic stroke (AIS) is characterized by acute neurological deterioration caused by progressive space-occupying brain edema, often occurring in the first hours to days after symptom onset. Without any treatment, the result is often fatal. Despite advances in treatment for AIS, up to 80% of patients with a large hemispheric stroke or cerebellar stroke are at risk of poor outcome. Decompressive surgery can be life-saving in a subgroup of patients with malignant AIS, but uncertainties exist on patient selection, predictors of malignant infarction, peri...
Source: Seminars in Neurology - August 18, 2023 Category: Neurology Authors: Krishnan, Kailash Hollingworth, Milo Nguyen, Thanh N. Kumaria, Ashwin Kirkman, Matthew A. Basu, Surajit Tolias, Christos Bath, Philip M. Sprigg, Nikola Tags: Review Article Source Type: research

Train-your-brain program to reduce depression, anxiety, and stress in stroke survivors: a pilot community-based cognitive intervention study
DiscussionThe TYB program provided group support and validation, resulting in improved mood and reduced stress among stroke survivors. Cultural collectivism played a significant role in fostering group cohesion. However, the program’s limited focus on caregivers and timing of assessments during the December holidays may have affected the outcomes. The TYB program demonstrated feasibility and potential effectiveness in alleviating psychological distress and enhancing cognitive function among stroke survivors. Future research should explore long-term effects, larger sample sizes, and non-English-speaking populations to enh...
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research

Monitoring Risk and Preventing Ischemic Stroke in the Very Old
This article examines current guidelines and evidence regarding medical management, lifestyle changes, and psychosocial interactions that can contribute to the primary and secondary prevention of ischemic stroke in the very old.AREAS COVERED: The authors conducted a literature search for ischemic stroke prevention and risk assessment in the elderly via PubMed. Furthermore, they describe current strategies for monitoring risk and preventing ischemic stroke in the elderly population.EXPERT OPINION: Ischemic stroke poses a significant health risk to the elderly, with prevention relying on managing modifiable risk factors such...
Source: Expert Review of Neurotherapeutics - August 4, 2023 Category: Neurology Authors: Mychael Delgardo Grant Rubin Thilan Tudor Anthony J Tang Geoffrey Reeves E Sander Connolly Source Type: research

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