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Orally Administered Crocin Protects Against Cerebral Ischemia/Reperfusion Injury Through the Metabolic Transformation of Crocetin by Gut Microbiota
Conclusion Collectively, pharmacokinetic and pharmacodynamic association studies provide evidence that the gut microbiota plays a vital role in the fate of crocin and crocetin in the gastrointestinal tract. In addition, the cross-interaction between gut microbiota and crocin might mediate the activation of the cerebral-protective effect of orally administered crocin. Ethics Statement This study was carried out in accordance with the recommendations of ‘Institutional Animal Research Committee guidelines, Animal Ethics Committee of China Pharmaceutical University.’ The protocol was approved by the ‘An...
Source: Frontiers in Pharmacology - April 29, 2019 Category: Drugs & Pharmacology Source Type: research

Long-Term Exposure to Transportation Noise in Relation to Development of Obesity —a Cohort Study
Conclusion: Our results link transportation noise exposure to development of obesity and suggest that combined exposure from different sources may be particularly harmful. https://doi.org/10.1289/EHP1910 Received: 17 March 2017 Revised: 5 October 2017 Accepted: 9 October 2017 Published: 20 November 2017 Address correspondence to A. Pyko, Institute of Environmental Medicine, Karolinska Institutet, SE-171 77 Stockholm, Sweden. Telephone: 46(0) 852487561. Email: Andrei.pyko@ki.se Supplemental Material is available online (https://doi.org/10.1289/EHP1910). The authors declare they have no actual or potential competing fina...
Source: EHP Research - November 20, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Life situation 5  years after subarachnoid haemorrhage
ConclusionsIn this 5‐year follow‐up after SAH, the participants reported to have a greater number of hidden disabilities compared to physical problems, whereas most had acceptable participation in society. A yearly follow‐up after a SAH could be suggested aiming to improving the cognitive and mental health.
Source: Acta Neurologica Scandinavica - September 4, 2017 Category: Neurology Authors: H. C. Persson, L. Carlsson, K. S. Sunnerhagen Tags: ORIGINAL ARTICLE Source Type: research

Burden of disease from road traffic and railway noise – a quantification of healthy life years lost in Sweden
Conclusions Road traffic and railway noise contribute significantly to the burden of disease in Sweden each year. The total numbe r of DALY should, however, be interpreted with caution due to limitations in data quality.byEriksson C, Bodin T, Selander J. doi:10.5271/sjweh.3651
Source: Scandinavian Journal of Work, Environment and Health - June 9, 2017 Category: Occupational Health Tags: Original article Source Type: research

Burden of disease from road traffic and railway noise - a quantification of healthy life years lost in Sweden.
Conclusions Road traffic and railway noise contribute significantly to the burden of disease in Sweden each year. The total number of DALY should, however, be interpreted with caution due to limitations in data quality. PMID: 28599022 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Work, Environment and Health - June 9, 2017 Category: Occupational Health Authors: Eriksson C, Bodin T, Selander J Tags: Scand J Work Environ Health Source Type: research