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U.S. FDA Approves New Pediatric Formulation of SIRTURO ® (bedaquiline) as Part of Combination Therapy to Treat Children with Pulmonary Multidrug-Resistant Tuberculosis
NEW BRUNSWICK, NJ, May 27, 2020 — The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) has granted approval for a new pediatric formulation of SIRTURO® (bedaquiline). SIRTURO® is now indicated for use as part of combination therapy in the treatment of adult and pediatric patients (5 years and older and weighing at least 15 kg) with pulmonary multidrug-resistant tuberculosis (MDR‑TB). In the U.S., the medicine should be reserved for use when an effective treatment regimen cannot otherwise be provided. This indication received accelerated appro...
Source: Johnson and Johnson - May 27, 2020 Category: Pharmaceuticals Tags: Innovation Source Type: news

All Your Coronavirus Questions, Answered
One of the worst symptoms of any plague is uncertainty—who it will strike, when it will end, why it began. Merely understanding a pandemic does not stop it, but an informed public can help curb its impact and slow its spread. It can also provide a certain ease of mind in a decidedly uneasy time. Here are some of the most frequently asked questions about the COVID-19 pandemic from TIME’s readers, along with the best and most current answers science can provide. A note about our sourcing: While there are many, many studies underway investigating COVID-19 and SARS-CoV-19, the novel coronavirus that causes the illn...
Source: TIME: Health - April 14, 2020 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized COVID-19 Explainer Source Type: news

Tropical Travel Trouble 010 Fever, Arthralgia and Rash
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 010 Peer Reviewer: Dr Jennifer Ho, ID physician QLD, Australia You are an ED doc working in Perth over schoolies week. An 18 yo man comes into ED complaining of fever, rash a “cracking headache” and body aches. He has just hopped off the plane from Bali where he spent the last 2 weeks partying, boozing and running amok. He got bitten by “loads” of mosquitoes because he forgot to take insect repellent. On examination he looks miserable,...
Source: Life in the Fast Lane - July 16, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine arthralgia dengue fever rash Source Type: blogs

Tropical Travel Trouble 009 Humongous HIV Extravaganza
LITFL • Life in the Fast Lane Medical Blog LITFL • Life in the Fast Lane Medical Blog - Emergency medicine and critical care medical education blog aka Tropical Travel Trouble 009 The diagnosis of HIV is no longer fatal and the term AIDS is becoming less frequent. In many countries, people with HIV are living longer than those with diabetes. This post will hopefully teach the basics of a complex disease and demystify some of the potential diseases you need to consider in those who are severely immunosuppressed. While trying to be comprehensive this post can not be exhaustive (as you can imagine any patient with a low ...
Source: Life in the Fast Lane - July 7, 2018 Category: Emergency Medicine Authors: Amanda McConnell Tags: Clinical Cases Tropical Medicine AIDS art cryptococcoma cryptococcus HIV HIV1 HIV2 PEP PrEP TB toxoplasma tuberculoma Source Type: blogs

The First Outbreak of Autochthonous Zika Virus in Sabah, Malaysian Borneo
Conclusions Surveillance, risk assessment, and intervention were strengthened throughout Malaysia in response to the 2016 outbreak of ZIKV in neighboring Singapore. The Malaysian Ministry of Health undertook regular surveillance from June 2015 during the South American outbreak, but no ZIKV was detected in 784 samples tested up to August 2016 (https://kpkesihatan.com/2016/08/28/kenyataan-akhbar-kpk-28-ogos-2016-situasi-terkini-virus-zika-di-malaysia/). However, during the peak of the 2016 Singapore ZIKV outbreak from September through December 2016, eight out of 849 samples tested were positive for ZIKV (https://kpkesiha...
Source: PLOS Currents Outbreaks - May 1, 2018 Category: Epidemiology Authors: Jiloris Julian Frederick Dony Source Type: research

In this era of increased globalization, infectious diseases show no boundaries
Devastating. That alone cannot fully describe the extent of the destruction of property, the displacement of tens of thousands of residents, the injuries and loss of life in the wake of Hurricanes Harvey and Irma. As Americans, our hearts ache for those affected by the flooding. As a medical student, former international development worker in Afghanistan and EMT in South Africa, I also lay awake thinking about the many infectious diseases that take hold in disaster and flood settings. In major floods and other natural disasters, rising water levels and damage to sewage treatment plants lead to contaminated water supplies, ...
Source: Kevin, M.D. - Medical Weblog - September 21, 2017 Category: General Medicine Authors: < a href="http://www.kevinmd.com/blog/post-author/sarah-lawrence" rel="tag" > Sarah Lawrence < /a > Tags: Conditions Infectious Disease Primary Care Public Health & Policy Source Type: blogs

Staying Healthy While Traveling This Summer
As summer approaches and temperatures climb, travelers are planning trips to warm and tropical destinations, many of which have been affected by the Zika Virus. In addition to booking that plane ticket and reading up on local activities, it is critical that travelers learn how best to protect themselves from Zika and other mosquito-borne diseases including malaria. Zika, which has continued making global headlines since its recent resurgence, is a virus that spreads through either the bite of an infected Aedes aegypti mosquito or sexual transmission. This type of mosquito thrives in warmer climates and is found throughou...
Source: Healthy Living - The Huffington Post - April 26, 2016 Category: Consumer Health News Source Type: news

7 Expert-Backed Tips For Staying Healthy On Your Next Big Trip
As spring approaches, you may be thinking about this year’s summer getaway. Or maybe you’re an Type A planner who is already booking a Thanksgiving or Christmas trip. Whatever your travel style, here's something you probably haven't considered: How to stay healthy while abroad. While you probably won’t make a Pinterest board of vaccinations with the same enthusiasm as you pin must-eat pastries and stylish travel outfits, taking care of your health on a trip might just save your life. Here are seven tips to help keep your vacations as stress- and sickness-free as possible:  1. First, call your doctor....
Source: Healthy Living - The Huffington Post - March 23, 2016 Category: Consumer Health News Source Type: news

What Treatment is Available for Malaria?
Discussion Malaria is a life-threatening yet preventable and curable disease caused by parasites. In humans, there are 4 species that cause malaria: Plasmodium falciparum, Plasmodium vivax, Plasmodium malariae,and Plasmodium ovale. Plasmodium falciparum is the most deadly and Plasmodium falciparum and Plasmodium vivax are the most common. Plasmodium parasites are transmitted by bites from Anopheles mosquitoes from an infected human. The incubation period is 7-30 days. In 2012, it is estimated to have caused 627,000 deaths mostly among African children. Mortality rates have been decreasing but children, pregnant women, peop...
Source: PediatricEducation.org - April 7, 2014 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

The Behind the Headlines 2013's Top Five of Top Fives
As we move towards the end of the year, like all news sources, we fall back on that classic space filler – the list story. So without further ado, here is the official Behind the Headlines Top Five of Top Fives stories of 2013.   The top five "Good work team!" stories of the year We can often get bogged down in pointing out dodgy sub-group analyses, spurious extrapolations of samples sizes containing just four men and a dog, and RCTs pointing out the benefits of chocolate on blood pressure that turned out to be funded by a chocolate-making conglomerate. So it's important not to lose sight of the fact that ther...
Source: NHS News Feed - December 31, 2013 Category: Consumer Health News Tags: QA articles Medical practice Source Type: news

NIH and Other Public Private Partnerships to Research Treatments for Multiple Diseases
Over the past few weeks, the National Institutes of Health (NIH) has made a number of important announcements regarding collaborations with industry as well as the funding of several new research initiatives. Below is a summary of these stories. NIH Partners With Eli Lilly and Others on Rare Diseases FierceBiotechResearch reported that NIH selected four (4) new preclinical drug development studies to uncover new therapies for rare diseases. The projects will be funded through the Therapeutics for Rare and Neglected Diseases (TRND) program under NIH's National Center for Advancing Translational Sciences, NCATS, which ...
Source: Policy and Medicine - October 4, 2013 Category: Health Medicine and Bioethics Commentators Authors: Thomas Sullivan Source Type: blogs

Twerking Disease: The Definitive Medical Resource For Doctors.
This study was published in Time magazine so it must be true.  In addition, the story was picked up by 95.8 THE BONE and was described by a self proclaimed expert twerker jockey between songs about booty slappin' and G-thangs.      EXERCISE Studies have shown most folks watching Richard Simmons in "Twerking to the Oldies" have been cured of their twerking addiction.      MIRROR THERAPY Consider buying a full length wall mirror for full therapeutic effect.  Alternatively, take a video of yourself twerking while checking yourself out in a mirror, put it on YouTube and let ever...
Source: The Happy Hospitalist - September 7, 2013 Category: Internists and Doctors of Medicine Authors: Tamer Mahrous Source Type: blogs