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Condition: Pregnancy
Drug: Nicotine

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Total 862 results found since Jan 2013.

Demystifying the impact of prenatal tobacco exposure on the placental immune microenvironment: Avoiding the tragedy of mending the fold after death
This study aims to meticulously examine the repercussions of PTE on placental immune landscapes, employing a coordinated research methodology encompassing bioinformatics, machine learning and animal studies. Concurrently, it aims to screen biomarkers and potential compounds that could sensitively indicate and mitigate placental immune disorders. In the course of this research, two gene expression omnibus (GEO) microarrays, namely GSE27272 and GSE7434, were included. Gene set enrichment analysis (GSEA) and immune enrichment investigations on differentially expressed genes (DEGs) indicated that PTE might perturb numerous inn...
Source: J Cell Mol Med - September 13, 2023 Category: Molecular Biology Authors: Xiaoxuan Zhao Yuepeng Jiang Xiao Ma Qujia Yang Xinyi Ding Hanzhi Wang Xintong Yao Linxi Jin Qin Zhang Source Type: research

Cigarette Smoking Abstinence Among Pregnant Individuals Using E-Cigarettes or Nicotine Replacement Therapy
CONCLUSIONS AND RELEVANCE: These findings suggest that individuals who used e-cigarettes during pregnancy had a higher smoking abstinence rate in late pregnancy than individuals who used NRT, especially for those who initiated e-cigarette use before pregnancy, indicating that replacement of cigarettes with e-cigarettes during pregnancy may be a viable strategy for harm reduction.PMID:37698863 | DOI:10.1001/jamanetworkopen.2023.30249
Source: Cancer Control - September 12, 2023 Category: Cancer & Oncology Authors: Xiaozhong Wen Minseon V Chung Kayla A Liszewski Lauren D Todoro Eve M Giancarlo Wenxin Zhang Sara K Berkelhamer Maciej L Goniewicz Source Type: research

Pharmacological and electronic cigarette interventions for smoking cessation in adults: component network meta-analyses
CONCLUSIONS: The most effective interventions were nicotine e-cigarettes, varenicline and cytisine (all high certainty), as well as combination NRT (additive effect, certainty not rated). There was also high-certainty evidence for the effectiveness of nicotine patch, fast-acting NRT and bupropion. Less certain evidence of benefit was present for nortriptyline (moderate certainty), non-nicotine e-cigarettes and tapering of nicotine dose (both low certainty). There was moderate-certainty evidence that bupropion may slightly increase the frequency of SAEs, although there was also the possibility of no increased risk. There wa...
Source: Cochrane Database of Systematic Reviews - September 11, 2023 Category: General Medicine Authors: Nicola Lindson Annika Theodoulou Jos é M Ordóñez-Mena Thomas R Fanshawe Alex J Sutton Jonathan Livingstone-Banks Anisa Hajizadeh Sufen Zhu Paul Aveyard Suzanne C Freeman Sanjay Agrawal Jamie Hartmann-Boyce Source Type: research

Effectiveness of smoking cessation interventions among pregnant women: An updated systematic review and meta-analysis
CONCLUSIONS: Non-pharmacological interventions for smoking cessation are the most effective for pregnant women. The moderator analysis suggests that pregnant women of low socioeconomic status might benefit less from smoking cessation interventions than women of a high socioeconomic status. These women are usually heavier smokers that live in pro-smoking environments and could require more intensive and targeted interventions.PMID:37683574 | DOI:10.1016/j.addbeh.2023.107854
Source: Addictive Behaviors - September 8, 2023 Category: Addiction Authors: A Vila-Farinas M P érez-Rios A Montes-Martinez A Ruano-Ravina Ariadna Forray J Rey-Brandariz C Candal-Pedreira E Fern ández B Casal-Acci ón L Varela-Lema Source Type: research

Assessment of urinary aromatic amines in Brazilian pregnant women and association with DNA damage: Influence of genetic diversity, lifestyle, and environmental and socioeconomic factors
Environ Pollut. 2023 Aug 10;335:122366. doi: 10.1016/j.envpol.2023.122366. Online ahead of print.ABSTRACTAromatic amines (AAs) are polar organic chemicals with a wide environmental distribution originating from various sources, such as tobacco smoke, diesel exhaust, and dermal absorption from textile products with azo dyes. The toxicity profile of AAs is directly related to the amino group's metabolic activation and the generation of the reactive intermediate, forming DNA adducts and potential carcinogenicity. Urinary levels of 8-hydroxy-2'-deoxyguanosine (8OHdG) are an important biomarker of DNA damage. Since AAs have bee...
Source: Environmental Pollution - August 12, 2023 Category: Environmental Health Authors: Mar ília Cristina Oliveira Souza Neus Gonz ález Joaquim Rovira Marta Herrero Montse Marqu ès Mart í Nadal Fernando Barbosa Jos é Luis Domingo Source Type: research

Clinical Practice Guideline of Spanish Society of Pneumology and Thoracic Surgery (SEPAR) on Pharmacological Treatment of Tobacco Dependence 2023
CONCLUSIONS: The answers to the 12 questions allow us to extract recommendations and algorithms for the pharmacological treatment of tobacco dependence.PMID:37567792 | DOI:10.1016/j.arbres.2023.07.024
Source: Archivos de Bronconeumologia - August 11, 2023 Category: Respiratory Medicine Authors: Carlos R ábade-Castedo Jos é Ignacio de Granda-Orive Juan Antonio Riesco-Miranda Eva De Higes-Mart ínez Ángela Ramos-Pinedo Eva Cabrera-C ésar Jaime Signes-Costa Mi ñana Marcos Garc ía Rueda Esther Pastor-Espl á Carlos A Jim énez-Ruiz Source Type: research