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Total 2124 results found since Jan 2013.

Effects of Iron Polymaltose Complex, Ferrous Fumarate and Ferrous Sulfate Treatments in Anemic Pregnant Rats, Their Fetuses and Placentas.
In this study, the effects of oral iron polymaltose complex (IPC), ferrous fumarate (FF) and ferrous sulfate (FS) were compared in anemic pregnant rats, their fetuses and placentas. Hematological variables and oxidative stress markers in the liver, heart and kidneys of the dams and fetuses as well as the markers for oxidative stress, inflammation and hypoxia in placentas were assessed. Pregnancy outcome was measured by number of fetuses, and by neonate and placental weight. All therapies were comparably effective in correcting anemia. FS and FF, but not IPC, resulted in liver damage in dams and oxidative stress in dams, fe...
Source: Inflammation and Allergy Drug Targets - April 1, 2013 Category: Allergy & Immunology Authors: Toblli JE, Cao G, Oliveri L, Angerosa M Tags: Inflamm Allergy Drug Targets Source Type: research

Vitamin D in Pregnancy and Early LifeVitamin D in Pregnancy and Early Life
Over the last decade the rates of food allergy and eczema have continued to increase dramatically in children. Will vitamin D for mom's-to-be reverse the trend? Expert Review of Clinical Immunology
Source: Medscape Allergy Headlines - November 20, 2013 Category: Allergy & Immunology Tags: Allergy & Clinical Immunology Journal Article Source Type: news

Impact of Altered Early Infant gut Microbiota Following Breastfeeding and Delivery Mode on Allergic Diseases.
Abstract The prevalence of allergic diseases among infants is increasing particularly in developed countries. Although, the exact reason is not clear yet, one of the most probable explanations is reducing microbial exposure during early life and consequent alteration of gut microbiota. Various factors including delivery mode, infant`s diet, environment and antibiotics administration by mothers are involved in microbial colonization of infant`s intestine. Since the content of infant`gut microbiota plays a critical role in the maturation and development of the immune system, it determines the risk of immune diseases...
Source: Inflammation and Allergy Drug Targets - December 4, 2013 Category: Allergy & Immunology Authors: Fooladi AA, Khani S, Hosseini HM, Mousavi SF, Aghdam EM, Nourani MR Tags: Inflamm Allergy Drug Targets Source Type: research

Gastroesophagial reflux disease and asthma in pregnant women with dyspnea.
In conclusion, the prevalence of GERD was quite high in pregnant women, irrespective of the fact that they were asthmatic or non-asthmatic. Further studies evaluating women throughout pregnancy will inform us more about this relationship. PMID: 24338255 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - December 19, 2013 Category: Allergy & Immunology Authors: Bidad K, Heidarnazhad H, Pourpak Z, Shayestefar G, Moayeri H, Zendehdel N Tags: Iran J Allergy Asthma Immunol Source Type: research

Abortion in Iranian legal system: a review.
Abstract Abortion traditionally means, "to miscarry" and is still known as a problem which societies has been trying to reduce its rate by using legal means. Despite the pregnant women and fetuses have being historically supported; abortion was firstly criminalized in 1926 in Iran, 20 years after establishment of modern legal system. During next 53 years this situation changed dramatically, so in 1979, the time of Islamic Revolution, aborting fetuses before 12 weeks and therapeutic abortion (TA) during all the pregnancy length was legitimate, based on regulations that used medical justification. After 1979 the sit...
Source: Iranian Journal of Allergy, Asthma and Immunology - December 19, 2013 Category: Allergy & Immunology Authors: Abbasi M, Shamsi Gooshki E, Allahbedashti N Tags: Iran J Allergy Asthma Immunol Source Type: research

Maternal hemoglobin levels during pregnancy and asthma in childhood: the Generation R Study.
PMID: 24439422 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - January 15, 2014 Category: Allergy & Immunology Authors: Tromp II, Gaillard R, Kiefte-de Jong JC, Steegers EA, Jaddoe VW, Duijts L, Hofman A, de Jongste JC, Moll HA Tags: Ann Allergy Asthma Immunol Source Type: research

Perinatal influences on the development of asthma and atopy in childhood.
CONCLUSION: Factors affecting the in utero environment, such as maternal atopy and infections, and bacterial exposure in pregnancy or early life may act as immunomodulators enhancing or inhibiting the development of asthma and atopy in childhood. PMID: 24468253 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - February 1, 2014 Category: Allergy & Immunology Authors: Illi S, Weber J, Zutavern A, Genuneit J, Schierl R, Strunz-Lehner C, von Mutius E Tags: Ann Allergy Asthma Immunol Source Type: research

Regulation of TH17 markers early in life through maternal farm exposure
Conclusions: Gene expression of TH17 lineage markers in cord blood was not influenced by maternal farming. Yet TH17 and Treg cell markers were positively correlated and influenced by maternal farm exposure. Our data suggest that prenatal exposures and genetic predisposition play a role during early TH17 immune maturation, potentially regulating the development of immune-mediated diseases, such as childhood asthma.
Source: Journal of Allergy and Clinical Immunology - November 25, 2013 Category: Allergy & Immunology Authors: Anna Lluis, Nikolaus Ballenberger, Sabina Illi, Maximilian Schieck, Michael Kabesch, Thomas Illig, Isolde Schleich, Erika von Mutius, Bianca Schaub Tags: Mechanisms of allergy and clinical immunology Source Type: research

Relative perinatal safety of salmeterol vs formoterol and fluticasone vs budesonide use during pregnancy.
CONCLUSION: This study does not provide evidence of greater perinatal safety for one LABA or one ICS over the other. PMID: 24656659 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - March 18, 2014 Category: Allergy & Immunology Authors: Cossette B, Beauchesne MF, Forget A, Lemière C, Larivée P, Rey E, Blais L Tags: Ann Allergy Asthma Immunol Source Type: research

HLA-G allele and Haplotype Frequencies in a Healthy Population of Iran.
According to this study, the most prevalent alleles in the Iranian population were G*01:01:01:01 (52.5%), G*01:01:02 (16%) and G*01:04:03 (14.5%) and also the lowest alleles regarding the frequency were G*01:01:01:06 (0.5%) and G*01:03 (0.5%). The results of G*01:01:01:01 and G*01:04:01 frequencies showed some similarities with the polish population. Our results were similar to the north Indian population for the frequencies of G*01:06 and G*01:01:02. PMID: 24659125 [PubMed - in process]
Source: Iranian Journal of Allergy, Asthma and Immunology - March 29, 2014 Category: Allergy & Immunology Authors: Kuroshli Z, Gourabi H, Bazrgar M, Sanati MH, Bahraminejad E, Anisi K Tags: Iran J Allergy Asthma Immunol Source Type: research

Maternal consumption of dairy products, calcium, and vitamin D during pregnancy and infantile allergic disorders.
CONCLUSION: Higher maternal intake of total dairy products, cheese, yogurt, and calcium during pregnancy may reduce the risk of infantile eczema, physician-diagnosed asthma, physician-diagnosed atopic eczema, and physician-diagnosed atopic eczema, respectively. Higher maternal intake of vitamin D during pregnancy may increase the risk of infantile eczema. PMID: 24950846 [PubMed - in process]
Source: Annals of Allergy, Asthma and Immunology - June 26, 2014 Category: Allergy & Immunology Authors: Miyake Y, Tanaka K, Okubo H, Sasaki S, Arakawa M Tags: Ann Allergy Asthma Immunol Source Type: research

Arginase I levels are decreased in the plasma of pediatric patients with atopic dermatitis.
CONCLUSION: In AD, a different mechanism of arginine metabolism seems to be stimulated, leading to the formation of nitric oxide pathway components causing suppression of the arginase pathway and impairment in skin hydration, collagen synthesis, and wound healing. PMID: 25027824 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - July 11, 2014 Category: Allergy & Immunology Authors: Dimitriades V, Rodriguez PC, Zabaleta J, Ochoa AC Tags: Ann Allergy Asthma Immunol Source Type: research

The HLA-G 14bp insertion/deletion polymorphism in Women with Recurrent Spontaneous Abortion.
Abstract HLA-G is a non-classical HLA class Ib molecule with limited protein variability generated by alternative splicing. HLA-G displays immunotolerant properties and hence plays important roles in the maintenance of a successful pregnancy and maternal tolerance of the semiallogenic fetus. Polymorphism of the HLA-G gene may potentially affect the biological properties of the protein, and a 14-bp insertion/deletion polymorphism in exon 8 of the 3' untranslated region (3' UTR) of the HLA-G gene is thought to influence HLA-G expression. To study the association of the 14-bp insertion/deletion (INDEL) polymorphism w...
Source: Iranian Journal of Allergy, Asthma and Immunology - August 31, 2014 Category: Allergy & Immunology Authors: Afkhami F, Shekari Khaniani M, Farzadi L, Paknejad Z, Mansoori Derakhshan S Tags: Iran J Allergy Asthma Immunol Source Type: research

Developmental programming of allergic diseases.
Authors: Pincus M, Arck P Abstract Emerging evidence reveals that the incidence of allergic disorders commencing during childhood is influenced by pre-, peri- and early postnatal environmental challenges. We here highlight biomarkers involved in the purported interaction of a challenged intrauterine environment during pregnancy and the risk for allergies in the children later in life. We propose that the identification of biomarkers during pregnancy may allow early detection of children prone to develop allergies and possibly other chronic immune diseases. Subsequently, therapeutic interventions designed to prevent...
Source: Chemical Immunology and Allergy - December 2, 2014 Category: Allergy & Immunology Tags: Chem Immunol Allergy Source Type: research

State of the Art: Medical treatment of aspirin exacerbated respiratory disease (AERD).
Abstract Aspirin exacerbated respiratory disease (AERD) is characterized as adult onset asthma, nasal polyps, chronic rhinosinusitis, and hypersensitivity to a cyclooxygenase-1 (COX-1) inhibitor, viz aspirin or nonsteroidal antiinflammatory drugs (NSAIDs). The method for diagnosing AERD is with aspirin challenge, and treatment includes aspirin desensitization followed by continued daily aspirin. Although oral challenge has been the mainstay in the United States, lysyl-aspirin has been validated as a diagnostic tool for aspirin-sensitive asthma and will be discussed further in this article. The challenges with aspi...
Source: American Journal of Rhinology and Allergy - January 1, 2015 Category: ENT & OMF Authors: Ta V, Simon R Tags: Am J Rhinol Allergy Source Type: research