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Vaccination: Vaccines

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Total 1365 results found since Jan 2013.

Emergence of Marburg virus: a global perspective on fatal outbreaks and clinical challenges
The Marburg virus (MV), identified in 1967, has caused deadly outbreaks worldwide, the mortality rate of Marburg virus disease (MVD) varies depending on the outbreak and virus strain, but the average case fatality rate is around 50%. However, case fatality rates have varied from 24 to 88% in past outbreaks depending on virus strain and case management. Designated a priority pathogen by the National Institute of Allergy and Infectious Diseases (NIAID), MV induces hemorrhagic fever, organ failure, and coagulation issues in both humans and non-human primates. This review presents an extensive exploration of MVD outbreak evolu...
Source: Frontiers in Microbiology - September 13, 2023 Category: Microbiology Source Type: research

Development and evaluation of a multi-epitope subunit vaccine against Mycoplasma synoviae infection
In this study, our objective is to develop a multi-epitope vaccine for M. synoviae (MSMV) and to evaluate the immune responses and protective efficacy of MSMV in chickens. We successfully identified a total of 14 B-cell, 5 MHC-I, and 16 MHC-II binding epitopes from the immunodominant proteins RS01790, BMP, GrpE, RS00900, and RS00275. Subsequently, we synthesized the multi-epitope vaccine by connecting all conserved epitopes using appropriate linkers. The resulting MSMV demonstrated notable antigenicity, non-allergenic properties, and stability. Notably, the MSMV effectively stimulated high levels of antibody production in ...
Source: International Journal of Biological Macromolecules - September 4, 2023 Category: Biochemistry Authors: Guihua Zhang Lejiabao Han Yuying Zhao Quan Li Shifeng Wang Huoying Shi Source Type: research

Comprehensive care of adults with respiratory diseases must include vaccines
Ann Allergy Asthma Immunol. 2023 Sep;131(3):292-293. doi: 10.1016/j.anai.2023.05.023.NO ABSTRACTPMID:37661170 | DOI:10.1016/j.anai.2023.05.023
Source: Annals of Allergy, Asthma and Immunology - September 3, 2023 Category: Allergy & Immunology Authors: Barbara P Yawn Dennis Williams Gregory Poland Source Type: research

A qualitative investigation into vaccine hesitancy and confidence amongst people managing allergy
Ann Allergy Asthma Immunol. 2023 Aug 29:S1081-1206(23)01208-5. doi: 10.1016/j.anai.2023.08.600. Online ahead of print.NO ABSTRACTPMID:37652234 | DOI:10.1016/j.anai.2023.08.600
Source: Annals of Allergy, Asthma and Immunology - August 31, 2023 Category: Allergy & Immunology Authors: Ayel Luis R Batac Kaitlyn A Merrill Michael A Golding Elissa M Abrams Philippe B égin Moshe Ben-Shoshan Erika Ladouceur Leslie E Roos Vladan Protudjer Jennifer L P Protudjer Source Type: research

Egg allergy and yellow fever vaccination
CONCLUSION: There is a relationship between the positivity of the egg's components and the severity of the clinical reaction. Furthermore, the relationship between the positivity of the tests with the YFV and egg's components may show a tendency to look at ovomucoid and conalbumin, but it is not a certainty. Therefore, further studies are needed to confirm these associations, and for now, the authors still recommend using the vaccine for testing when necessary.PMID:37597532 | DOI:10.1016/j.jped.2023.07.004
Source: Jornal de Pediatria - August 19, 2023 Category: Pediatrics Authors: B árbara L B Cançado Carolina S Aranda Marcia C Mallozi Lily Y Weckx Dirceu Sol é Source Type: research