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Impact of Procedure Volume on the Outcomes of Surgical Aortic Valve Replacement
CONCLUSION: Patients treated in very low volume centers (≤25 operations/year) had a similar risk regarding in-hospital mortality and most complications compared with very high-volume centers (>100 operations/year). Only in the case of acute kidney injury, very high-volume centers showed better outcomes than very low volume centers. Therefore, surgical aortic valve replacement can be performed safely independent of case volume.PMID:35917823 | DOI:10.1055/s-0042-1754352
Source: The Thoracic and Cardiovascular Surgeon - August 2, 2022 Category: Cardiovascular & Thoracic Surgery Authors: Vera Oettinger Klaus Kaier Constantin von Zur M ühlen Manfred Zehender Christoph Bode Friedhelm Beyersdorf Peter Stachon Wolfgang Bothe Source Type: research

EE392 Cost-Effectiveness Analysis of Atrial Fibrillation Screening for a 50 –65-Year-Old Population With Elevated Stroke Risk
Atrial fibrillation (AF) is one of the main risk factors for strokes. European guidelines recommend screening measures to detect AF for the age group above 65 years. Cost-effectiveness of a telemetric AF-detection method (Preventicus Heartbeats) was demonstrated for the age group above 65 years for Germany. Below 65 years screening is only recommended with presence of risk factors, usually assessed by CHA2DS2-VASc score. This analysis examines the cost-effectiveness of telemetric AF-screening for the population aged 50-65 years in Germany with CHA2DS2-VASc score of minimum 1 (men) or minimum 2 (women).
Source: Value in Health - December 1, 2022 Category: International Medicine & Public Health Authors: S Wahler, A M üller, R Birkemeyer, JM von der Schulenburg Source Type: research

Vitamin-K-antagonist phenprocoumon versus direct oral anticoagulants in patients with atrial fibrillation: a real-world analysis of German claims data
Conclusions The small superiority or non-inferiority of DOACs over warfarin seen in the RCTs might not translate into relevant advantages of DOACs over phenprocoumon. To confirm the hypothesis, an RCT with phenprocoumon is needed. Next to the safety and effectiveness assessments other factors might also play a substantial role in the decision on the right OAC for stroke prevention.
Source: BMJ Open - January 2, 2023 Category: General Medicine Authors: Warkentin, L., Klohn, F., Deiters, B., Kühlein, T., Hueber, S. Tags: Open access, Pharmacology and therapeutics Source Type: research

Prevalence of peripheral arterial disease, abdominal aortic aneurysm, and risk factors in the Hamburg City Health Study: A Cross-Sectional Analysis
CONCLUSION: In this large population-based cohort study of 10,000 subjects from Hamburg, Germany, a strikingly high prevalence of PAD was revealed. Almost 45% suffered from any index disease, while AAA was only diagnosed in 1.3% of males and 0.2% of females. The high prevalence of atherosclerotic disease and associated cardiovascular risk factors underline that it is essential to increase awareness and fuel efforts for secondary prevention.PMID:36634745 | DOI:10.1016/j.ejvs.2023.01.002
Source: PubMed: Eur J Vasc Endovasc ... - January 12, 2023 Category: Surgery Authors: Christian-Alexander Behrendt G ötz Thomalla David Leander Rimmele Elina Larissa Petersen Raphael Twerenbold Eike Sebastian Debus Tilo K ölbel Stefan Blankenberg Christian Schmidt-Lauber Frederik Peters Birgit-Christiane Zyriax Source Type: research

Anticoagulant Treatment Adherence and Persistence in German Patients with Atrial Fibrillation
ConclusionsPatients with AF receiving edoxaban had significantly higher adherence and persistence compared with those receiving VKAs. This trend was also seen in NOAC QD regimens vs. NOAC BID regimens for adherence. These results provide insight into how adherence and persistence may contribute to the effectiveness of edoxaban for stroke prevention in patients with AF in Germany.
Source: Cardiology and Therapy - May 3, 2023 Category: Cardiology Source Type: research

Clinical Course and Recurrence in Transient Global Amnesia: A Study From the TEMPiS Telestroke Network
CONCLUSIONS: Arterial hypertension is prevalent in TGA patients, with elevated blood pressure being the most-frequent concomitant condition. In our cohort, recurrence of TGA occurred in approximately one-fifth of patients. Concomitant conditions such as migraine, hypothyroidism, and atrial fibrillation occurred at different frequencies in the two groups.PMID:37455507 | DOI:10.3988/jcn.2022.0368
Source: Journal of Clinical Neurology - July 17, 2023 Category: Neurology Authors: Shadi Taheri Nils Peters Annaelle Zietz Berthold Abel Gordian Hubert Filip Barinka Hanni Wiestler Irena Kovacic Ralf Linker Felix Schlachetzki Roland Backhaus Source Type: research

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