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Condition: Arteriosclerosis
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Total 413 results found since Jan 2013.
Important recommendations of the German-Austrian S3 guidelines on management of extracranial carotid artery stenosis
CONCLUSION: Both CEA and CAS necessitate a critical evaluation of the indications and strict quality criteria. Future studies should evaluate even better selection criteria for an individual, optimal, conservative, operative or endovascular treatment.PMID:35318494 | DOI:10.1007/s00104-022-01622-x
Source: Der Chirurg - March 23, 2022 Category: Surgery Authors: Hans-Henning Eckstein Andreas K ühnl Michael Kallmayer Source Type: research
Intracranial Arterial Calcification and Intracranial Atherosclerosis: Close but Different
CONCLUSION: Our multimodal imaging-based comparison study on intracranial arteriosclerosis demonstrated that intimal IAC, compared with medial IAC, was more often accompanied by the luminal stenosis, larger plaque burden, eccentricity, and IPH, providing strong evidence for clinical evaluation on the mechanism, risk, and prognosis of ischemic stroke.PMID:35211084 | PMC:PMC8861312 | DOI:10.3389/fneur.2022.799429
Source: Atherosclerosis - February 25, 2022 Category: Cardiology Authors: Heng Du Jia Li Wenjie Yang Daniel Bos Lu Zheng Lawrence Ka Sing Wong Thomas W Leung Xiangyan Chen Source Type: research
False Utopia of One Unifying Description of the Vulnerable Atherosclerotic Plaque: A Call for Recalibration That Appreciates the Diversity of Mechanisms Leading to Atherosclerotic Disease
Arterioscler Thromb Vasc Biol. 2022 Feb 10:ATVBAHA121316693. doi: 10.1161/ATVBAHA.121.316693. Online ahead of print.ABSTRACTAtherosclerosis is a complex disease characterized by the formation of arterial plaques with a broad diversity of morphological phenotypic presentations. Researchers often apply one description of the vulnerable plaque as a gold standard in preclinical and clinical research that could be applied as a surrogate measure of a successful therapeutic intervention, despite the variability in lesion characteristics that may underly a thrombotic occlusion. The complex mechanistic interplay underlying progress...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 10, 2022 Category: Cardiology Authors: Gerard Pasterkamp Hester M den Ruijter Chiara Giannarelli Source Type: research
Intracranial Arterial Calcification and Intracranial Atherosclerosis: Close but Different
ConclusionOur multimodal imaging-based comparison study on intracranial arteriosclerosis demonstrated that intimal IAC, compared with medial IAC, was more often accompanied by the luminal stenosis, larger plaque burden, eccentricity, and IPH, providing strong evidence for clinical evaluation on the mechanism, risk, and prognosis of ischemic stroke.
Source: Frontiers in Neurology - February 8, 2022 Category: Neurology Source Type: research
How Single-Cell Technologies Have Provided New Insights Into Atherosclerosis
Arterioscler Thromb Vasc Biol. 2022 Feb 3:ATVBAHA121315849. doi: 10.1161/ATVBAHA.121.315849. Online ahead of print.ABSTRACTThe development of innovative single-cell technologies has allowed the high-dimensional transcriptomic and proteomic profiling of individual blood and tissue cells. Recent single-cell studies revealed a new cellular heterogeneity of atherosclerotic plaque tissue and allowed a better understanding of distinct immune functional states in the context of atherosclerosis. In this brief review, we describe how single-cell technologies have shed a new light on the cellular composition of atherosclerotic plaqu...
Source: Arteriosclerosis, Thrombosis and Vascular Biology - February 3, 2022 Category: Cardiology Authors: Natalia Eberhardt Chiara Giannarelli Source Type: research
Trimethylamine N-oxide-a marker for atherosclerotic vascular disease
Rev Cardiovasc Med. 2021 Sep 24;22(3):787-797. doi: 10.31083/j.rcm2203085.ABSTRACTAs a potential causative factor in various cardiovascular diseases, the gut microbe-generated metabolite trimethylamine N-oxide (TMAO) has courted considerable research interest as a potential biomarker. TMAO is a small molecule considered to be beneficial for the health of deep-water animals due to its ability to protect proteins against hydrostatic pressure stress. However, it may cause deleterious effects in humans as mounting evidence suggests that TMAO may enhance atherosclerosis, independent of traditional risk factors. This may be medi...
Source: Reviews in Cardiovascular Medicine - September 26, 2021 Category: Cardiology Authors: Guinan Xie An Yan Peng Lin Yi Wang Liping Guo Source Type: research
