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Specialty: Cardiology
Condition: Arrhythmia
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Total 3162 results found since Jan 2013.
PPP1R12C Promotes Atrial Hypocontractility in Atrial Fibrillation
CONCLUSIONS: Patients with AF exhibit increased levels of PPP1R12C protein compared with controls. PPP1R12C overexpression in mice increases PP1c targeting to MLC2a and causes MLC2a dephosphorylation, which reduces atrial contractility and increases AF inducibility. These findings suggest that PP1 regulation of sarcomere function at MLC2a is a key determinant of atrial contractility in AF.PMID:37737016 | DOI:10.1161/CIRCRESAHA.123.322516
Source: Circulation Research - September 22, 2023 Category: Cardiology Authors: Srikanth Perike Francisco J Gonzalez-Gonzalez Issam Abu-Taha Frederick W Damen Laurin M Hanft Ken S Lizama Anahita Aboonabi Andrielle E Capote Yuriana Aguilar-Sanchez Benjamin Levin Zhenbo Han Arvind Sridhar Jacob Grand Jody Martin Joseph G Akar Chad M Wa Source Type: research
Elimination of CaMKII δ Autophosphorylation by CRISPR-Cas9 Base Editing Improves Survival and Cardiac Function in Heart Failure in Mice
CONCLUSIONS: Ablation of CaMKIIδ autophosphorylation by adenine base editing may offer a potential broad-based therapeutic concept for human cardiac disease.PMID:37712250 | DOI:10.1161/CIRCULATIONAHA.123.065117
Source: Circulation - September 15, 2023 Category: Cardiology Authors: Simon Lebek Xurde M Caravia Francesco Chemello Wei Tan John R McAnally Kenian Chen Lin Xu Ning Liu Rhonda Bassel-Duby Eric N Olson Source Type: research
Mental illness and cardiovascular health: observational and polygenic score analyses in a population-based cohort study
CONCLUSIONS: Our study shows widespread associations of (genetic liability to) mental illness (primarily depressive disorder) with CVD, even after confounder adjustment. Future research should focus on clarifying potential causal pathways between mental illness and CVD.PMID:37706306 | DOI:10.1017/S0033291723002635
Source: Atherosclerosis - September 14, 2023 Category: Cardiology Authors: R R Veeneman J M Vermeulen M Bialas A K Bhamidipati A Abdellaoui M R Munaf ò D Denys C R Bezzina K J H Verweij R Tadros J L Treur Source Type: research
A Comprehensive Review of Myocardial Bridging: Exploring Diagnostic and Treatment Modalities
Cureus. 2023 Aug 8;15(8):e43132. doi: 10.7759/cureus.43132. eCollection 2023 Aug.ABSTRACTMyocardial bridging (MB) is a congenital coronary artery anomaly involving an overlying myocardium's partial or complete encasement of a coronary artery segment. The obstruction can lead to significant cardiac symptoms, resulting in myocardial ischemia, arrhythmia, and sudden cardiac death. Several approaches, including invasive and non-invasive methods, have been proposed to diagnose and manage MB. Invasive modalities, such as intravascular ultrasound (IVUS) and coronary angiography, offer high specificity and sensitivity. In contrast...
Source: Atherosclerosis - September 11, 2023 Category: Cardiology Authors: Endurance O Evbayekha Enyioma Nwogwugwu Adedoyin Olawoye Kafayat Bolaji Adeyemi A Adeosun Abimbola O Ajibowo G Chinenye Nsofor Vivian N Chukwuma Hameed O Shittu Chinwendu A Onuegbu Adewale M Adedoyin Okelue E Okobi Source Type: research
JCS/JHRS 2022 Guideline on Diagnosis and Risk Assessment of Arrhythmia
Circ J. 2023 Sep 11. doi: 10.1253/circj.CJ-22-0827. Online ahead of print.NO ABSTRACTPMID:37690816 | DOI:10.1253/circj.CJ-22-0827
Source: Circulation Journal - September 10, 2023 Category: Cardiology Authors: Bonpei Takase Takanori Ikeda Wataru Shimizu Haruhiko Abe Takeshi Aiba Masaomi Chinushi Shinji Koba Kengo Kusano Shinichi Niwano Naohiko Takahashi Seiji Takatsuki Kaoru Tanno Eiichi Watanabe Koichiro Yoshioka Mari Amino Tadashi Fujino Yu-Ki Iwasaki Ritsuko Source Type: research
Effects of air pollution on cardiovascular events in cardiac intensive care units
Ann Cardiol Angeiol (Paris). 2023 Sep 7;72(5):101663. doi: 10.1016/j.ancard.2023.101663. Online ahead of print.ABSTRACTMany environmental factors influence the occurrence of cardiovascular events. Among these, air pollution is certainly the most harmful, due to its dual composition and effects. Air pollution is both particulate and gaseous, and can vary in concentration and composition according to its source and type of emission. Moreover, clinical effects are not only observed at long-term but also at short-term, following rapid deterioration in air quality. Air pollution must therefore be seen both as a risk factor for ...
Source: Annales de Cardiologie et d'Angeiologie - September 9, 2023 Category: Cardiology Authors: J F Argacha Source Type: research
Spontaneous Recovery of Isolated Advanced Heart Block in Patient with Celiac Disease by Starting a Strict Gluten Free Diet: A Case Report and Review of the Literature
We report a case of a 50-year-old woman with a known case of celiac disease who presented with a symptomatic cardiac conduction abnormality that improved with a gluten-free diet.LEARNING POINTS: Celiac disease is a malabsorptive long-term autoimmune disorder where the small intestine is the primarily affected organ due to gluten intolerance and affects 1% of the general population.Cardiovascular pathology, including dilated cardiomyopathy, myocarditis, arrhythmias, and premature atherosclerosis, was found to be more prevalent in patients with celiac disease than in others without celiac disease.The association of celiac di...
Source: Atherosclerosis - September 8, 2023 Category: Cardiology Authors: Ossama Maadarani Leila Bigdelu Zouheir Bitar Mohammad Alhabibi Hosni Kabbara Source Type: research
