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Specialty: Cardiovascular & Thoracic Surgery
Condition: Thrombosis
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Total 372 results found since Jan 2013.
Dual antiplatelet therapy at discharge: Antiplatelet practice patterns after coronary artery bypass grafting, surgical anecdote is driving standard of care
Thrombosis and platelet aggregation are key pathogenic mechanisms in acute coronary syndromes (ACS). Dual antiplatelet therapy (DAPT) with aspirin and a P2Y12 inhibitor has been demonstrated to reduce death from cardiovascular causes, nonfatal myocardial infarction, and stroke after ACS.1-3 These large randomized controlled trials studied heterogeneous populations of patients with ACS treated with medical therapy, percutaneous coronary intervention, or coronary bypass grafting (CABG). The data supporting DAPT after CABG are less robust and limited to observational studies, subgroup analyses, and smaller randomized studies ...
Source: The Journal of Thoracic and Cardiovascular Surgery - November 8, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Mark Helmers, Pavan Atluri Tags: Editorial commentary Source Type: research
Interventional closure of patent foramen ovale with Nit ‐occlud® device in prevention of recurrent neurologic events—Long‐term results
ConclusionsThe Nit‐Occlud PFO device and its delivery system are safe and provides sufficient closure of PFO in patients who suffered from cryptogenic stroke, TIA or paradoxical peripheral embolism. It is associated with high procedural success and favorable rates of complete closure.
Source: Catheterization and Cardiovascular Interventions - October 25, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Aleksander Araszkiewicz, Sylwia S ławek, Olga Trojnarska, Maciej Lesiak, Marek Grygier Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research
Heparin: Effects upon the Glycocalyx and Endothelial Cells.
Authors: Spiess BD
Abstract
Unfractionated heparin (UFH) is the most widely used injectable medication in the United States. UFH is a poly-dispersed, relatively impure combination of many polysaccharides known as a glycosaminoglycan. It is used as the primary anticoagulant for heart surgery as well as for active treatment of deep venous thrombosis, vascular thrombosis, stroke, and many other potentially catastrophic clotting syndromes. Many perfusionists and cardiac team members know little of the biology of UFH other than its use for cardiopulmonary bypass. UFH is very similar to heparin sulfate, found on the surf...
Source: Journal of Extra-Corporeal Technology - October 7, 2017 Category: Cardiovascular & Thoracic Surgery Tags: J Extra Corpor Technol Source Type: research
Risk of Intraatrial Thrombi After Thoracoscopic Ablation in Absence of Heparin and Appendage Closure.
CONCLUSIONS: Thoracoscopic ablation of AF can be associated with a risk of left atrial appendage thrombus formation and possibly also stroke. With administration of heparin during the ablation, followed by occlusion of the left atrial appendage as a part of the procedure, this risk can be effectively reduced.
PMID: 28433223 [PubMed - indexed for MEDLINE]
Source: The Annals of Thoracic Surgery - September 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Budera P, Osmancik P, Herman D, Talavera D, Petr R, Straka Z Tags: Ann Thorac Surg Source Type: research
Risk of Intraatrial Thrombi After Thoracoscopic Ablation in Absence of Heparin and Appendage Closure
Conclusions Thoracoscopic ablation of AF can be associated with a risk of left atrial appendage thrombus formation and possibly also stroke. With administration of heparin during the ablation, followed by occlusion of the left atrial appendage as a part of the procedure, this risk can be effectively reduced.
Source: The Annals of Thoracic Surgery - August 25, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research
Single trans ‐septal access technique for left atrial intracardiac echocardiography to guide left atrial appendage closure
ConclusionsThis initial experience suggests that LAA occlusion with the Amplatzer Amulet device using ICE guidance from the left atrium via a single trans‐septal technique is feasible and safe.
Source: Catheterization and Cardiovascular Interventions - August 24, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Daniel Aguirre, Christian Pincetti, Luis Perez, Carlos Deck, Mario Alfaro, Maria Jesus Vergara, Gabriel Maluenda Tags: Valvular and Structural Heart Diseases Source Type: research
Long-Term Risk of Ischemic Stroke After the Cox-Maze III Procedure for Atrial Fibrillation
Conclusions This multicenter study showed a low incidence of perioperative and long-term postoperative ischemic stroke/TIA after CM-III. Although general risk of ischemic stroke/TIA was reduced, patients with CHA2DS2-VASc score 2 or greater had a higher risk compared with score 0 or 1. Complete left atrial appendage excision may be an important reason for the low ischemic stroke rate.
Source: The Annals of Thoracic Surgery - July 20, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research
Left atrial appendage occlusion with the AMPLATZER Amulet device: periprocedural and early clinical/echocardiographic data from a global prospective observational study.
CONCLUSIONS: This large real-world prospective registry of catheter-based LAAO using the AMPLATZER Amulet device reports a high implant success rate and a low periprocedural complication rate in a population with a high risk of stroke and bleeding. Transoesophageal echo data confirm good closure rates during follow-up and low rates of device-associated thrombus.
PMID: 28649053 [PubMed - as supplied by publisher]
Source: EuroIntervention - June 28, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Early Anticoagulation drug regimens after WATCHMAN Left Atrial Appendage Closure: safety and efficacy.
CONCLUSIONS: LAA closure with the Watchman device is feasible in patients with relative or absolute contraindication to oral anticoagulation. Neither DAPT nor NOAC therapy lead to a significant increase in device thrombus, stroke or bleeding compared to the standard VKA regimen. NOAC therapy had the numerically lowest event rate.
PMID: 28606886 [PubMed - as supplied by publisher]
Source: EuroIntervention - June 16, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Pulmonary hypertension and right heart failure due to severe hypernatremic dehydration.
CONCLUSION: A high index of suspicion is paramount to diagnose pulmonary hypertension and aggressive correction of the acidosis and hypoxia is needed. In the presence of severe right ventricular failure, ECMO can be used as a bridge to recovery while underlying metabolic derangements are being corrected.
PMID: 28553778 [PubMed - in process]
Source: Perfusion - May 30, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Chiwane S, Ahmed TM, Bauerfeld CP, Chauhan M Tags: Perfusion Source Type: research
Duration of dual antiplatelet therapy following drug ‐eluting stent implantation: A systemic review and meta‐analysis of randomized controlled trials with longer follow up
ConclusionsIn the present analysis of RCTs with longer follow up (2 years or longer), S‐DAPT compared with L‐DAPT, was associated with higher rate of MI and lower rate of major bleeding without any significant difference in the rates of all cause mortality, cardiac mortality, ST, TVR, and stroke.
Source: Catheterization and Cardiovascular Interventions - May 30, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Abhishek Sharma, Sahil Agrawal, Aakash Garg, Ajay Vallakati, Carl J. Lavie, Gerald Helft Tags: CORONARY ARTERY DISEASE Source Type: research
Emergency HeartWare Ventricular Assist Device (HVAD) exchange due to pump thrombosis using minimally invasive technique.
This report documents the very first LVAD pump exchange as well as the first one performed via a minimally invasive approach in Poland.
PMID: 28515757 [PubMed - in process]
Source: Polish Journal of Cardio-Thoracic Surgery - May 19, 2017 Category: Cardiovascular & Thoracic Surgery Tags: Kardiochir Torakochirurgia Pol Source Type: research
30-day results from prospective multi-specialty evaluation of carotid artery stenting using the CGuard micronet-covered embolic prevention stent system in real world multicenter clinical practice: the IRON-GUARD study.
CONCLUSIONS: Multi-center multi-specialty use of the CGuard EPS in routine clinical practice was associated with no major peri-procedural neurologic complications and a total elimination of post-procedural neurologic complications by 30 days.
PMID: 28485278 [PubMed - as supplied by publisher]
Source: EuroIntervention - May 10, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research
Comparison of antithrombotic agents during urgent percutaneous coronary intervention following thrombolytic therapy: A retrospective cohort study
ConclusionIn STEMI patients undergoing PCI within 24 hr after thrombolytic therapy, bivalirudin was associated with a strong trend toward reduced bleeding complications as compared to heparin alone or heparin plus GPI.The optimal antithrombotic regiment for urgent PCI following thrombolytic therapy is currently unknown. Our study demonstrated that use of bivalirudin during PCI following thrombolytic therapy is associated with a trend toward reduced bleeding complications compared to heparin alone or heparin plus GPI. Large randomized trials of adjunctive anticoagulation during PCI in this complex post‐thrombolytic popula...
Source: Catheterization and Cardiovascular Interventions - April 18, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Jaya R. Mallidi, Peter Robinson, Paul F. Visintainer, Amir S. Lotfi, Scott Mulvey, Gregory R. Giugliano Tags: Coronary Artery Disease Source Type: research
Percutaneous coronary intervention or coronary artery bypass grafting for unprotected left main coronary artery disease
ConclusionsIn patients with unprotected left main coronary disease and low to intermediate SYNTAX score, PCI might be an acceptable alternative to CABG. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 14, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ahmed N. Mahmoud, Islam Y. Elgendy, Amgad Mentias, Marwan Saad, Walid Ibrahim, Mohammad K. Mojadidi, Ramez Nairooz, Parham Eshtehardi, R. David Anderson, Habib Samady Tags: Coronary Artery Disease Source Type: research
