Stroke RSS Page 16

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Specialty: Cardiology
Condition: Thrombosis

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Total 3531 results found since Jan 2013.

Spatial Transcriptional Mapping Reveals Site-Specific Pathways Underlying Human Atherosclerotic Plaque Rupture
CONCLUSIONS: Our findings show plaque site-specific transcriptional signatures associated with proximal rupture-prone regions of carotid atherosclerotic plaques. This led to the geographical mapping of novel therapeutic targets, such as matrix metallopeptidase 9, against plaque rupture.PMID:37286250 | DOI:10.1016/j.jacc.2023.04.008
Source: Atherosclerosis - June 7, 2023 Category: Cardiology Authors: Jiangming Sun Pratibha Singh Annelie Shami Ewelina Kluza Mengyu Pan Djordje Djordjevic Natasha Barascuk Michaelsen Cecilia Kennb äck Nicole N van der Wel Marju Orho-Melander Jan Nilsson Ivan Formentini Karin Conde-Knape Esther Lutgens Andreas Edsfeldt Is Source Type: research

NET-(works) in arterial and venous thrombo-occlusive diseases
Front Cardiovasc Med. 2023 May 22;10:1155512. doi: 10.3389/fcvm.2023.1155512. eCollection 2023.ABSTRACTFormation of Neutrophil Extracellular Traps (NETosis), accompanied by the release of extracellular decondensed chromatin and pro-inflammatory as well as pro-thrombotic factors, is a pivotal element in the development and progression of thrombo-occlusive diseases. While the process of NETosis is based on complex intracellular signalling mechanisms, it impacts a wide variety of cells including platelets, leukocytes and endothelial cells. Consequently, although initially mainly associated with venous thromboembolism, NETs al...
Source: Atherosclerosis - June 7, 2023 Category: Cardiology Authors: Monika Zdanyte Oliver Borst Patrick M ünzer Source Type: research

SR-B1-/-ApoE-R61h/h Mice Mimic Human Coronary Heart Disease
Cardiovasc Drugs Ther. 2023 Jun 5. doi: 10.1007/s10557-023-07475-8. Online ahead of print.ABSTRACTCardiovascular diseases are the leading cause of death in the modern world. Atherosclerosis underlies the majority of these pathologies and may result in sudden life-threatening events such as myocardial infarction or stroke. Current concepts consider a rupture (resp. erosion) of "unstable/vulnerable" atherosclerotic plaques as a primary cause leading to thrombus formation and subsequent occlusion of the artery lumen finally triggering an acute clinical event. We and others described SR-B1-/-ApoE-R61h/h mice mimicking clinical...
Source: Atherosclerosis - June 5, 2023 Category: Cardiology Authors: Andrea Star šíchová Source Type: research

Plasma ANGPTL8 Levels and Risk for Secondary Cardiovascular Events in Japanese Patients With Stable Coronary Artery Disease Receiving Statin Therapy
CONCLUSIONS: Monitoring ANGPTL8 levels over time might be useful to assess residual risk of cardiovascular secondary events in patients with cardiovascular disease undergoing statin therapy.PMID:37259862 | DOI:10.1161/ATVBAHA.122.318880
Source: Arteriosclerosis, Thrombosis and Vascular Biology - June 1, 2023 Category: Cardiology Authors: Jun Morinaga Kosuke Kashiwabara Daisuke Torigoe Yusuke Okadome Kenichi Aizawa Kohei Uemura Ai Kurashima Eiji Matsunaga Hirotaka Fukami Haruki Horiguchi Michio Sato Taichi Sugizaki Keishi Miyata Tsuyoshi Kadomatsu Masashi Mukoyama Katsumi Miyauchi Seiji Ho Source Type: research

Is carotid web an arterial wall dysplasia? A histological series
CONCLUSION: Histological features in our 9 cases strengthen carotid web characterization as a homogeneous pattern of localized intimal hyperplasia. It is a unique entity consistent with intimal fibroplasia, distinct from medial fibromuscular dysplasia and early atherosclerosis.PMID:37263518 | DOI:10.1016/j.carpath.2023.107544
Source: Atherosclerosis - June 1, 2023 Category: Cardiology Authors: Louise Z Wang David Calvet Pierre Julia Val érie Domigo Nassim Mohamedi Jean-Marc Alsac Salma El Batti Emmanuel Messas Tristan Mirault Patrick Bruneval Guillaume Goudot Source Type: research

Short Versus Long-Term Dual Antiplatelet Therapy in Patients at High Bleeding Risk Undergoing PCI in Contemporary Practice: A Systemic Review and Meta-analysis
ConclusionShort-term DAPT after PCI in HBR patients was associated a reduction in major bleeding events and similar ischemic outcomes. However, a higher risk of ischemic stroke and MI at 1 year of follow-up was seen in some subsets.
Source: Cardiology and Therapy - June 1, 2023 Category: Cardiology Source Type: research

Five-Year Prognostic Value of DAPT Score in Older Patients undergoing Percutaneous Coronary Intervention: A Large-Sample Study in the Real World
CONCLUSION: This study suggested that in older PCI patients, the DAPT score did not show predictive value for MACCE; however, it had a certain predictive value for 5-year BARC 2, 3, or 5 bleeding.PMID:37258235 | DOI:10.5551/jat.64212
Source: Journal of Atherosclerosis and Thrombosis - May 31, 2023 Category: Cardiology Authors: Kailun Yan Pei Zhu Xiaofang Tang Yulong Li Jiawen Li Deshan Yuan Weixian Yang Yuejin Yang Runlin Gao Bo Xu Jinqing Yuan Xueyan Zhao Source Type: research

Epidemiology of Stroke in a General Japanese Population: The Hisayama Study
J Atheroscler Thromb. 2023 May 30. doi: 10.5551/jat.RV22004. Online ahead of print.ABSTRACTThe Hisayama Study is an ongoing epidemiological study of stroke, coronary artery disease (CAD), and other noncommunicable diseases in a general Japanese population established in 1961. According to the longitudinal data from the Hisayama Study, average levels of systolic blood pressure among hypertensive individuals have decreased with time since 1961. In contrast, the prevalence of metabolic risk factors such as obesity, hypercholesterolemia, and glucose intolerance has increased with time. The incidence rates of ischemic stroke in...
Source: Journal of Atherosclerosis and Thrombosis - May 31, 2023 Category: Cardiology Authors: Jun Hata Toshiharu Ninomiya Source Type: research

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