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Grade I traumatic aortic injury progression
This case highlights the importance of diagnosing Grade I aortic injuries after trauma. Although the prognosis for minimal aortic injury is typically quite good, the patient in this case suffered the unlikely complication of minimal intimal injury progression with resultant thromboembolism and massive stroke. Due to motion artifact and CT resolution limitations, the initial aortic injury was not detected. Thus, potentially life-saving measures such as serial CT monitoring of injury, blood pressure control, and endovascular repair were unable to be performed.
Source: Clinical Imaging - April 3, 2020 Category: Radiology Authors: Luke Pecha, Barbara Pawley Tags: Cardiothoracic Imaging Source Type: research

Techniques and outcomes of total aortic arch repair with frozen elephant trunk for DeBakey I dissections.
This report focuses on the techniques and outcomes of TAR with FET for acute/chronic aortic dissection. A review of pooled literature including 27 observational studies showed in-hospital mortality, permanent stroke, and spinal cord injury rates of 8.4 %, 5.9 % and 2.6 % for acute aortic dissections, and 7.5 %, 4.0 % and 4.6 % for chronic aortic dissections, respectively. In most of the studies, complete false lumen thrombosis rate was achieved in 80% of patients at the level of FET for acute and chronic aortic dissections. Mid-term outcomes are equally promising. For chronic aortic dissections, positive remodeling of the ...
Source: The Journal of Cardiovascular Surgery - April 21, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Kawajiri H, Khasawneh MA, Pochettino A, Oderich GS Tags: J Cardiovasc Surg (Torino) Source Type: research

Total Arch Replacement with Concomitant Retrograde Stent Graft Deployment via Ministernotomy in Acute Aortic Dissection.
CONCLUSIONS: Retrograde TEVAR in combination with total arch replacement via an upper ministernotomy might be safe and effective in treating acute type A aortic dissection, with fairly low mortality and perioperative complications, and a very good rate of total false lumen thrombosis in midterm follow up. PMID: 32364906 [PubMed - as supplied by publisher]
Source: The Heart Surgery Forum - March 23, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Tran TQ, Nguyen AT Tags: Heart Surg Forum Source Type: research

Thoracic endovascular repair for retrograde acute type A aortic dissection as an alternative choice
ConclusionThoracic endovascular aortic repair could be a useful alternative surgical option for patients with retrograde acute type A aortic dissection with an entry in the descending aorta who are not suitable for conventional open surgery. Careful follow-up of such patients is mandatory.
Source: General Thoracic and Cardiovascular Surgery - June 9, 2020 Category: Cardiovascular & Thoracic Surgery Source Type: research

Outcomes of truncus arteriosus repair and predictors of mortality
Conclusion22q11.2 deletion syndrome was associated with an inverse risk of death despite having more noncardiac comorbidities; this patient subpopulation also had a higher length of stay and increased cost of hospitalization.
Source: Journal of Cardiac Surgery - June 18, 2020 Category: Cardiovascular & Thoracic Surgery Authors: Mohammed Hamzah, Hasan F. Othman, Kshama Daphtary, Rukmini Komarlu, Hany Aly Tags: ORIGINAL ARTICLE Source Type: research

189 Unexpected, Wanted and Kept: Management of a Pregnancy With Severe LV Dysfunction, Re-Do Mechanical Mitral Valve and Recurrent Arrythmias
We present the multidisciplinary management of a 31YO women with an unexpected pregnancy. Her background included congenital ASD and VSD, surgical repair of PDA and severe aortic coarctation at 2 weeks. Resection of sub-aortic membrane and repair of anterior mitral valve prolapse at 7 years. First mitral valve replacement (MVR) at 16 years of age (tissue valve), second MVR (mechanical) at 27 after presenting with a stroke due to valve thrombosis. LVEF 25% and severely dilated.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: K. Lander, C. O'Brien, D. Watson, R. Yadav Source Type: research

A 10-Year Aortic Center Experience with Hybrid Repair of Chronic “Residual” Aortic Dissection After Type A Repair
ConclusionIn a high-volume aortic center, hybrid repair of RAD is associated with good anatomical results and a low risk of perioperative morbidity and mortality, including that of patients treated in zone 0. A redo replacement of the ascending aortic segment is sometimes necessary to provide a safer proximal landing zone and reduce the risk of type 1 endoleak after TEVAR.
Source: Cardiovascular Drugs and Therapy - February 2, 2021 Category: Cardiology Source Type: research

Novel use of the Sentinel cerebral protection device during thrombosed septal occluder explant and Atriclip appendage closure
ConclusionsWe demonstrate the first successful use of an SCPD during surgical excision of a mal-deployed occluder. With its ease of use and safety, SCPD may have utility in surgeries with high cardio-embolic risk.
Source: Journal of Cardiac Surgery - May 31, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Cristina Nunez ‐Pellot, Jeet J. Mehta, Christopher J. Bitetzakis, Erol Belli, Bibhu D. Mohanty Tags: CASE REPORT Source Type: research

Five-Year Outcomes with Conformable GORE ® TAG® endoprosthesis used in traumatic aortic transections
CONCLUSIONS: Five-year outcomes verify the CTAG device is a safe, effective, and durable option for BAI patients undergoing TEVAR.PMID:34126073 | DOI:10.1016/j.athoracsur.2021.05.054
Source: The Annals of Thoracic Surgery - June 14, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Mark A Farber Kambhampaty V Krishnasastry Nimesh Desai Benjamin W Starnes Jon S Matsumura Beth C Tohill TAG 08-02 clinical trial investigators Source Type: research

Extent of mural thrombus is not associated with increased 5-year mortality following elective AAA repair
CONCLUSIONS: In our experience, the extent of mural thrombus in AAA does not influence long-term survival after elective repair. AAA repair may provide protection against circulating components of mural thrombus which have the potential to promote atherosclerotic-related adverse events. Patients with renal insufficiency and larger AAA have increased risk of mortality 5 years after elective repair.PMID:35331063 | DOI:10.1177/17085381211063282
Source: Vascular - March 25, 2022 Category: Surgery Authors: Bilal Siddiq Matthew Dejong Emily Decicco Tara Zielke Melissa D'Andrea Bernadette Aulivola Matthew Blecha Source Type: research

Endovascular Thrombectomy for Acute Arterial Mesenteric Ischaemia: No Benefit of Mechanical Over Manual Thrombus Aspiration
Early vessel recanalisation is the cornerstone of treatment of acute arterial mesenteric ischaemia (AMI) and can be achieved by either percutaneous endovascular techniques or open repair. Depending on the mechanism of superior mesenteric artery (SMA) occlusion, endovascular techniques include intra-arterial thrombolysis, thrombus aspiration, or stenting. Endovascular thrombus aspiration has been shown to be beneficial for cerebral stroke, lower limb ischaemia, and myocardial infarction. Regarding AMI, endovascular thrombus aspiration has only been evaluated in small series,1 and SMA thrombus aspiration methods (manual or m...
Source: European Journal of Vascular and Endovascular Surgery - May 11, 2022 Category: Surgery Authors: Lorenzo Garzelli, Iannis B. Abdallah, Alexandre Nuzzo, Olivier Corcos, Yves Castier, Maxime Ronot Tags: Research Letter Source Type: research

NO/cGMP/PKG pathway in platelets:the therapeutic potential of PDE5 inhibitors in platelet disorders
J Thromb Haemost. 2022 Aug 11. doi: 10.1111/jth.15844. Online ahead of print.ABSTRACTPlatelets are the "guardians" of the blood circulatory system. At sites of vessel injury, they ensure hemostasis and promote immunity and vessel repair. However, their uncontrolled activation is one of the main drivers of thrombosis. To keep circulating platelets in a quiescent state, the endothelium releases platelet antagonists including nitric oxide (NO) that acts by stimulating the intracellular receptor guanylyl cyclase (GC). The latter produces the second messenger cyclic guanosine-3',5'-monophosphate (cGMP) that inhibits platelet ac...
Source: Thrombosis and Haemostasis - August 11, 2022 Category: Hematology Authors: Anisa Degjoni Federica Campolo Lucia Stefanini Mary Anna Venneri Source Type: research

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