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Specialty: Cardiovascular & Thoracic Surgery
Condition: Thrombosis

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Total 372 results found since Jan 2013.

The management of patients with atrial fibrillation undergoing percutaneous coronary intervention with stent implantation: In‐hospital‐data from the Atrial Fibrillation undergoing Coronary Artery Stenting (AFCAS) study
ConclusionsThe majority of AF patients undergoing PCI‐S are at high stroke risk, and therefore VKA treatment should not be withdrawn and combined anticoagulant and antiplatelet treatment is warranted. Current management appears largely in accordance with current recommendations, whereby accounting for the limited occurrence of in‐hospital adverse ischemic and bleeding events. © 2013 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - June 13, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Axel Schlitt, Andrea Rubboli, Gregory H Lip, Heli Lahtela, Josè Valencia, Pasi P. Karjalainen, Michael Weber, Mika Laine, Paulus Kirchhof, Matti Niemelä, Saila Vikman, Michael Buerke, K.E. Juhani Airaksinen, Tags: Original Study Source Type: research

The management of patients with atrial fibrillation undergoing percutaneous coronary intervention with stent implantation
Current recommendations on the management of patients with atrial fibrillation (AF) undergoing percutaneous coronary intervention with stent (PCI‐S) essentially derive from small, single‐center, retrospective datasets. To obtain larger and better quality data, we carried out the prospective, multicenter Atrial Fibrillation undergoing Coronary Artery Stenting (AFCAS) study. Therefore, consecutive patients with history of or ongoing AF undergoing PCI‐S were enrolled, and occurrence of adverse ischemic and bleeding events recorded during 12 months follow‐up. In this article, we report the in‐hospital observations. O...
Source: Catheterization and Cardiovascular Interventions - August 28, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Axel Schlitt, Andrea Rubboli, Gregory Y.H. Lip, Heli Lahtela, Josè Valencia, Pasi P. Karjalainen, Michael Weber, Mika Laine, Paulus Kirchhof, Matti Niemelä, Saila Vikman, Michael Buerke, K.E. Juhani Airaksinen, Tags: Coronary Artery Disease Source Type: research

337-i * thoracoscopic left atrial appendectomy
Conclusions: This approach demonstrated feasibility, safety and effectiveness and should be considered as a possible alternative to percutaneous closure of the LAA. However, its effect on long-term prevention of stroke needs to be evaluated.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Guerra, M., Miranda, J., Martins, D., Neves, P., Gama, V., Vouga, L. Tags: Learning from experience (film) Source Type: research

Evaluation of the efficacy and safety of dual antiplatelet therapy with or without warfarin in patients with a clinical indication for DAPT and chronic anticoagulation: A meta‐analysis of observational studies
Conclusions: All‐cause mortality appears similar in patients treated with TT or DAPT although TT was associated with higher rates of major bleeding and a lower risk for ischemic stroke. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - September 10, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Chirag Bavishi, Anna Koulova, Sripal Bangalore, Ashwin Sawant, Saurav Chatterjee, Sameer Ather, Jose Valencia, Nikolaus Sarafoff, Andrea Rubboli, Juhani K. Airaksinen, Gregory Y. H. Lip, Jacqueline E. Tamis‐Holland Tags: Coronary Artery Disease Source Type: research

Efficacy and safety of routine thrombus aspiration in patients with ST‐segment elevation myocardial infarction undergoing primary percutaneous coronary intervention: An updated systematic review and meta‐analysis of randomized controlled trials
ConclusionsCompared with conventional PPCI for STEMI, adjunctive TA reduces the risk of subsequent MACE. However, the benefit in MACE is counterbalanced by an increased risk in stroke. Considering the above potential risks and benefits, TA should be considered in selected patients lesions rather than routinely. © 2015 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - November 19, 2015 Category: Cardiovascular & Thoracic Surgery Authors: Ioannis Mastoris, Gennaro Giustino, Samantha Sartori, Usman Baber, Roxana Mehran, Annapoorna S. Kini, Samin K. Sharma, George D. Dangas Tags: Coronary Artery Disease Source Type: research

Free-floating left atrial ball thrombus after mitral valve replacement with patent coronary artery bypass grafts: successful removal by a right minithoracotomy approach without aortic cross-clamp
We describe a case in a 79-year-old woman with chronic atrial fibrillation and a recent stroke who had undergone mitral valve replacement 25 years previously and coronary artery bypass grafting 5 years previously. Redo cardiac surgery represents a clinical challenge due to a higher rate of peri-operative morbidity and mortality. Median re-sternotomy can be particularly difficult in patients with functioning coronary artery grafts, where the risk of graft injury is a significant concern. Prompt surgical intervention was carried out, and to avoid the challenge of re-sternotomy in this patient with two prior thoracotomies, ...
Source: General Thoracic and Cardiovascular Surgery - May 22, 2016 Category: Cardiovascular & Thoracic Surgery Source Type: research

Transcatheter left atrial appendage occlusion in patients with atrial fibrillation and a high bleeding risk using aspirin alone for post-implant antithrombotic therapy.
CONCLUSIONS: LAAO with the ACP or Amulet was safely performed with ASA monotherapy after implantation without an increased risk of device-related thrombosis or stroke. PMID: 27973336 [PubMed - as supplied by publisher]
Source: EuroIntervention - December 16, 2016 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Percutaneous coronary intervention or coronary artery bypass grafting for unprotected left main coronary artery disease
ConclusionsIn patients with unprotected left main coronary disease and low to intermediate SYNTAX score, PCI might be an acceptable alternative to CABG. © 2017 Wiley Periodicals, Inc.
Source: Catheterization and Cardiovascular Interventions - March 14, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Ahmed N. Mahmoud, Islam Y. Elgendy, Amgad Mentias, Marwan Saad, Walid Ibrahim, Mohammad K. Mojadidi, Ramez Nairooz, Parham Eshtehardi, R. David Anderson, Habib Samady Tags: Coronary Artery Disease Source Type: research

Duration of dual antiplatelet therapy following drug ‐eluting stent implantation: A systemic review and meta‐analysis of randomized controlled trials with longer follow up
ConclusionsIn the present analysis of RCTs with longer follow up (2 years or longer), S‐DAPT compared with L‐DAPT, was associated with higher rate of MI and lower rate of major bleeding without any significant difference in the rates of all cause mortality, cardiac mortality, ST, TVR, and stroke.
Source: Catheterization and Cardiovascular Interventions - May 30, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Abhishek Sharma, Sahil Agrawal, Aakash Garg, Ajay Vallakati, Carl J. Lavie, Gerald Helft Tags: CORONARY ARTERY DISEASE Source Type: research

Risk of Intraatrial Thrombi After Thoracoscopic Ablation in Absence of Heparin and Appendage Closure
Conclusions Thoracoscopic ablation of AF can be associated with a risk of left atrial appendage thrombus formation and possibly also stroke. With administration of heparin during the ablation, followed by occlusion of the left atrial appendage as a part of the procedure, this risk can be effectively reduced.
Source: The Annals of Thoracic Surgery - August 25, 2017 Category: Cardiovascular & Thoracic Surgery Source Type: research

Risk of Intraatrial Thrombi After Thoracoscopic Ablation in Absence of Heparin and Appendage Closure.
CONCLUSIONS: Thoracoscopic ablation of AF can be associated with a risk of left atrial appendage thrombus formation and possibly also stroke. With administration of heparin during the ablation, followed by occlusion of the left atrial appendage as a part of the procedure, this risk can be effectively reduced. PMID: 28433223 [PubMed - indexed for MEDLINE]
Source: The Annals of Thoracic Surgery - September 1, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Budera P, Osmancik P, Herman D, Talavera D, Petr R, Straka Z Tags: Ann Thorac Surg Source Type: research

Interventional closure of patent foramen ovale with Nit ‐occlud® device in prevention of recurrent neurologic events—Long‐term results
ConclusionsThe Nit‐Occlud PFO device and its delivery system are safe and provides sufficient closure of PFO in patients who suffered from cryptogenic stroke, TIA or paradoxical peripheral embolism. It is associated with high procedural success and favorable rates of complete closure.
Source: Catheterization and Cardiovascular Interventions - October 25, 2017 Category: Cardiovascular & Thoracic Surgery Authors: Aleksander Araszkiewicz, Sylwia S ławek, Olga Trojnarska, Maciej Lesiak, Marek Grygier Tags: VALVULAR AND STRUCTURAL HEART DISEASES Source Type: research

Bioprosthetic aortic valve leaflet thrombosis detected by multidetector computed tomography is associated with adverse cerebrovascular events: a meta-analysis of observational studies.
CONCLUSIONS: MDCT-defined LT following ABV replacement is associated with a significantly increased risk of adverse cerebrovascular events. Further prospective studies are required to ascertain whether LT can be prevented or treated with pharmacological strategies. PMID: 29235436 [PubMed - as supplied by publisher]
Source: EuroIntervention - December 15, 2017 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Real world safety and efficacy of WATCHMAN LAA closure at one year in patients on dual antiplatelet therapy Results of the DAPT subgroup from the EWOLUTION all-comers study.
CONCLUSIONS: LAA closure with the WATCHMAN followed by DAPT therapy in a high risk patient population is safe. At one year the intervention is associated with a substantial risk reduction regarding ischemic stroke and major bleeding compared to the expected rate based on CHA2DS2-VASc and HAS-BLED scores. PMID: 29313819 [PubMed - as supplied by publisher]
Source: EuroIntervention - January 11, 2018 Category: Cardiovascular & Thoracic Surgery Tags: EuroIntervention Source Type: research

Comparing apples with oranges: The funfair of statistics
The CHA2DS2-VASc score estimates the risk of stroke in patients with atrial fibrillation.1,2 The CHA2DS2-VASc score accounts for congestive heart failure; hypertension; age of at least 75  years (doubled); diabetes mellitus; previous stroke, transient ischemic attack or thromboembolism (doubled); vascular disease; age 65 to 74 years; and sex category (female). Should the CHA2DS2-VASc score be considered as a categorical or a continuous factor, if the patients have an incremental in crease in risk of death, stroke, or bleeding?
Source: The Journal of Thoracic and Cardiovascular Surgery - August 3, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Ari A. Mennander Tags: Editorial Commentary Source Type: research