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Specialty: Hematology
Condition: Thrombosis

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Total 1625 results found since Jan 2013.

Risk factors and predictors for venous thromboembolism in people with ischemic stroke: A systematic review
In conclusion, this systematic review informs on several potential risk factors and predictors for VTE in people with ischemic stroke. To improve risk stratification and guide development of risk prediction models, further confirmation is needed, as there were few high-quality studies on each factor.PMID:35815351 | DOI:10.1111/jth.15813
Source: Thrombosis and Haemostasis - July 11, 2022 Category: Hematology Authors: Birgitte G T øndel V ânia M Morelli John-Bjarne Hansen Sigrid K Braekkan Source Type: research

Hypercoagulability on Thromboelastography Can Predict the Functional Outcome in Patients with Acute Ischemic Stroke
CONCLUSION: A R of <5 min was a negative predictor of functional independence. Frequent HT, END, and different stroke etiologies according to the R may be the cause of poor outcome after ischemic stroke.PMID:37130549 | DOI:10.1055/a-2084-5018
Source: Thrombosis and Haemostasis - May 2, 2023 Category: Hematology Authors: Jae-Chan Ryu Jae-Han Bae Sang Hee Ha Bum Joon Kim Sang-Beom Jeon Dong-Wha Kang Sun U Kwon Jong S Kim Jun Young Chang Source Type: research

Association between polycythemia and risk of ischemic stroke in males based on the National Health Insurance Service-Health Screening Cohort
CONCLUSIONS: The risk of ischemic stroke was higher in participants with polycythemia than in those with normocythemia.PMID:37249134 | DOI:10.1080/17474086.2023.2218610
Source: Expert Review of Hematology - May 30, 2023 Category: Hematology Authors: Hyo-Sun You Sang-Jun Shin Joungyoun Kim Hee-Taik Kang Source Type: research

Association between polycythemia and risk of ischemic stroke in males based on the national health insurance service-health screening cohort
CONCLUSIONS: The risk of ischemic stroke was higher in participants with polycythemia than in those with normocythemia.PMID:37249134 | DOI:10.1080/17474086.2023.2218610
Source: Expert Review of Hematology - May 30, 2023 Category: Hematology Authors: Hyo-Sun You Sang-Jun Shin Joungyoun Kim Hee-Taik Kang Source Type: research

Sexual dimorphism in peripheral blood cell characteristics linked to recanalization success of endovascular thrombectomy in acute ischemic stroke
AbstractEndovascular thrombectomy (EVT) success to treat  acute ischemic stroke varies with factors like stroke etiology and clot composition, which can differ between sexes. We studied if sex-specific blood cell characteristics (BCCs) are related to recanalization success. We analyzed electronic health records of 333 EVT patients from a single interve ntion center, and extracted 71 BCCs from the Sapphire flow cytometry analyzer. Through Sparse Partial Least Squares Discriminant Analysis, incorporating cross-validation and stability selection, we identified BCCs associated with successful recanalization (TICI 3) in ...
Source: Journal of Thrombosis and Thrombolysis - August 18, 2023 Category: Hematology Source Type: research

The impact of atherosclerotic vascular disease in predicting stroke, thromboembolism and mortality in atrial fibrillation patients: A systematic review
ConclusionAtherosclerotic vascular disease (eg. peripheral arterial disease, complex aortic plaque and prior MI) are significant predictors of stroke, thromboembolism and mortality in subjects with AF.© 2013 International Society on Thrombosis and Haemostasis
Source: Journal of Thrombosis and Haemostasis - February 1, 2013 Category: Hematology Authors: Branavan Anandasundaram, Deirdre Lane, Stavros Apostolakis, Gregory Y H Lip Tags: Original Article ‐ Vascular Biology Source Type: research

The impact of atherosclerotic vascular disease in predicting a stroke, thromboembolism and mortality in atrial fibrillation patients: a systematic review
ConclusionAtherosclerotic vascular disease (e.g. peripheral arterial disease, complex aortic plaque and prior MI) are significant predictors of a stroke, thromboembolism and mortality in subjects with AF.
Source: Journal of Thrombosis and Haemostasis - May 15, 2013 Category: Hematology Authors: B. Anandasundaram, D. A. Lane, S. Apostolakis, G. Y. H. Lip Tags: Original Article Source Type: research

Unanswered questions and research priorities to optimise stroke prevention in atrial fibrillation with the new oral anticoagulants.
Abstract This review article discusses the following, as yet unanswered, questions and research priorities to optimise patient management and stroke prevention in atrial fibrillation with the new direct oral anticoagulants (NOACs): 1. In patients prescribed a NOAC, can the anticoagulant effects or plasma concentrations of the NOACs be measured rapidly and reliably and, if so, can "cut-off points" between which anticoagulation is therapeutic (i.e. the "therapeutic range") be defined? 2. In patients who are taking a NOAC and bleeding (e.g. intracerebral haemorrhage), can the anticoagulant effects of the direct NOACs...
Source: Thrombosis and Haemostasis - November 28, 2013 Category: Hematology Authors: Hankey GJ Tags: Thromb Haemost Source Type: research

Clopidogrel High-on-Treatment Platelet Reactivity in Acute Ischemic Stroke Patients
Conclusions: Clopidogrel-HTPR was found in 44% of the patients with acute ischemic stroke. Besides time-dependency of the clopidogrel effect, major risk factors for clopidogrel-HTPR were diabetes mellitus and higher HbA1c values. Further investigations are required to analyse if a function test guided strategy has the potential to optimize the antiplatelet therapy of acute stroke patients.
Source: Thrombosis Research - January 9, 2014 Category: Hematology Authors: Saskia H. Meves, Kay D. Schröder, Heinz G. Endres, Christos Krogias, Jan C. Krüger, Horst Neubauer Tags: Platelets and cell biology Source Type: research

Feasibility and cost effectiveness of stroke prevention through community screening for atrial fibrillation using iPhone ECG in pharmacies. The SEARCH-AF study.
Abstract Atrial fibrillation (AF) causes a third of all strokes, but often goes undetected before stroke. Identification of unknown AF in the community and subsequent anti-thrombotic treatment could reduce stroke burden. We investigated community screening for unknown AF using an iPhone electrocardiogram (iECG) in pharmacies, and determined the cost-effectiveness of this strategy.Pharmacists performedpulse palpation and iECG recordings, with cardiologist iECG over-reading. General practitioner review/12-lead ECG was facilitated for suspected new AF. An automated AF algorithm was retrospectively applied to collecte...
Source: Thrombosis and Haemostasis - April 1, 2014 Category: Hematology Authors: Lowres N, Neubeck L, Salkeld G, Krass I, McLachlan AJ, Redfern J, Bennett AA, Briffa T, Bauman A, Martinez C, Wallenhorst C, Lau JK, Brieger DB, Sy RW, Freedman SB Tags: Thromb Haemost Source Type: research

Acute ischemic stroke patients with diabetes should not be excluded from intravenous thrombolysis
Abstract The benefit of intravenous thrombolysis (IVT) has been questioned for patients with diabetes mellitus (DM) in cases of acute ischemic stroke (IS). Our objective was to analyze the differences in outcome according to prior diagnosis of DM and the use or not of IVT. Observational study with inclusion of consecutive IS patients admitted to an stroke unit. Demographic data, vascular risk factors, comorbidity, stroke severity and 3-month follow-up outcome (modified Rankin Scale) were compared according to prior diagnosis of DM and the use or not of IVT. A total of 1,139 IS patients were admitted; 283 (24.8 %...
Source: Journal of Thrombosis and Thrombolysis - October 2, 2014 Category: Hematology Source Type: research

Ischemic stroke associated with immune thrombocytopenia
The objective of this study was to review all cases in literature in which the clinical manifestations of ischemic stroke and immune thrombocytopenia (ITP) were presented in the same patient including a new case of our own and discuss the possible mechanism and management of this syndrome. We reviewed 12 reports in which 18 cases were diagnosed as ischemic stroke and ITP. The clinical manifestations and ischemic lesion patterns of the 18 cases and our new case were analyzed in detail to elucidate the characteristics and management of this kind of syndrome. Of all the cases, 8 females and 10 males, 10 of them were Koreans; ...
Source: Journal of Thrombosis and Thrombolysis - November 8, 2014 Category: Hematology Source Type: research

Is plasma C3 and C4 levels useful in young cerebral ischemic stroke patients? Associations with prognosis at 3 months
Abstract Plasma complement C3 and C4 act as risk factor for vascular diseases related to atherosclerosis. The association C3 and C4 levels in young ischemic stroke patients with the prognosis were still not unknown. We conducted this study to establish the significance of admission C3 and C4 levels as a possible predictor of 3 months prognosis in young patients with acute ischemic stroke. We conducted this study in 1,451 young Chinese patients as determined by the modified Rankin Scale at 3 months. Bivariate logistic regression analyses were used to determine the risk factors of outcome in male and female patie...
Source: Journal of Thrombosis and Thrombolysis - February 1, 2015 Category: Hematology Source Type: research