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Specialty: Neurosurgery
Condition: Thrombosis
Education: Study
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Total 317 results found since Jan 2013.
E-026 Proximal vs distal occlusion in acute ischemic stroke: thrombus composition study
ConclusionWe found that proximal and distal occlusions have mostly similar thrombus compositions however the area of thrombus was different with two major components showing difference as well.Disclosures J. Arturo Larco: None. M. Abbasi: None. W. Brinjikji: 1; C; NIH RO1 STRIP REGISTRY.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Arturo Larco, J., Abbasi, M., Brinjikji, W. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-044 Patient outcomes after treatment of brain aneurysm in small diameter vessels with the silk vista baby flow diverter: a systematic review
ConclusionThis systematic review suggests that SVB is a safe and effective treatment for intracranial aneurysms in small vessels. Device trackability and reduced system dimensions, also facilitated the treatment of previously judged not amenable lesions, including a wide range of aneurysms located in anterior and posterior circulation distal vessels. Further prospective and comparative studies with patient outcome data specific to aneurysm location are needed to confirm the safety and efficacy of SVB.Disclosures R. Hanel: 1; C; Unrestricted research grant from NIH, Interline Endowment, Microvention, Stryker, CNX.. 2; C; Me...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hanel, R., Cortez, G., Benalia, V., Sheffels, E., Sutphin, D., Pederson, J., Pereira, V. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-048 Antithrombotics for emergent stenting in acute stroke
ConclusionTirofiban continuous infusion is a safe and possibly effective strategy for emergent stenting in acute ischemic stroke.Disclosures S. Lahoti: None. K. Limaye: None. C. Zevallos: None. K. Dlouhy: None. M. Hayakawa: None. E. Samaniego: None. D. Hasan: None. S. Ortega: 2; C; Medtronic, Stryker Neurovascular, Microvention. C. Derdeyn: 1; C; Siemens Healthineers. 4; C; Euphrates Vascular, Inc. 6; C; DSMB: Penumbra (MIND), NoNO (ESCAPE NA1 and FRONTIER).
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Lahoti, S., Limaye, K., Zevallos, C., Dlouhy, K., Hayakawa, M., Samaniego, E., Hasan, D., Ortega, S., Derdeyn, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-060 Analysis of reported adverse events of flow-diverter stents for intracranial aneurysms using the FDA MAUDE database
ConclusionsPost-market surveillance is an important to guide patient counselling and identify adverse events and device problems that were not identified in initial trials. Although there are inherent limitations to the MAUDE database, our results highlight some important PR and DR complications that can help optimize patient counseling and management.Disclosures M. Porwal: None. G. SenthilKumar: None. D. Kumar: None. G. Sinson: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Porwal, M., SenthilKumar, G., Kumar, D., Sinson, G. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-092 Use of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients
ConclusionUse of balloon-guide catheters for concomitant mechanical thrombectomy and carotid revascularization with flow-arrest results in significantly lower sICH and better 90-day outcomes in tandem stroke patients.Disclosures A. Baig: None. J. Neumaier: None. M. Waqas: None. A. Monteiro: None. J. Cappuzzo: None. W. Khawar: None. B. Donnelly: None. E. Levy: 2; C; : Claret Medical, GLG Consulting, Guidepoint Global, Imperial Care, Medtronic, Rebound, StimMed, Misionix, Mosiac, Clarion, IRRAS. 4; C; NeXtGen Biologics, RAPID Medical, Claret Medical, Cognition Medical, Imperative Care, Rebound Therapeutics, StimMed, Three Ri...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Baig, A., Neumaier, J., Waqas, M., Monteiro, A., Cappuzzo, J., Khawar, W., Donnelly, B., Levy, E., Siddiqui, A. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-096 COVID status is related to clot burden during thrombectomy in acute stroke patients
ConclusionOf 230 patients included in this interim analysis across 24 centers in the United States, between 02/2021 and 01/2022, 16 patients had a history of COVID. Comparing COVID-positive to non-positive, patients with COVID were younger (median 66.5 years vs 71.5 years, p 0.042), and had more intracranial clot by weight (median 101.0 mg vs 42.0 mg, p 0.047). There was a trend toward COVID positive patients to have more clot volume (median 180 cc vs 77.5 cc p 0.08), suggesting the difference was a higher clot burden instead of more density to the thrombus. These results suggest different histopathological characteristics...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fraser, J., Dabney, A., Vicari, J., Rivet, D., Woodward, B., Nanda, A., Fiorella, D., Baltan, S., Sohrabji, F., Pennypacker, K., Kellner, C. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-114 Rescue suction mechanical thrombectomy of medium-small vessel occlusion in a pediatric patient presented with acute ischemic stroke
ConclusionEndovascular aspiration mechanical thrombectomy of MSVO is feasible in pediatric patients presenting with AIS and associated with good functional outcome. Additionally, when acute ongoing neurological deficit is present and CTA is inconclusive, a digital subtraction angiography is deemed needed to identify MSVO as the yields of CTA diminishes significantly beyond LVO. Further studies are required.Disclosures R. Hart: None. A. Singh: None. C. Manzanero: None. Y. Lodi: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hart, R., Singh, A., Manzanero, C., Lodi, Y. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-164 Recurrent strokes as the initial presentation of colorectal adenocarcinoma
ConclusionCryptogenic strokes in patients with cancer are cardioembolic manifestations of cancer-mediated hypercoagulability such as NBTE, which consists of sterile, platelet-fibrin vegetations on cardiac valves. The mechanism of thromboembolism in patients with cancer is based on the interaction between tumor cells and leukocytes, which creates a thrombogenic vascular lining and induces the release of substances that activate the coagulation cascade. The diagnosis of NBTE should depend on the distribution of occluded vessels, identification of thrombus, and exclusion of other possible causes such as infective endocarditis...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Babici, D., Phillip Johansen, P., Rodriguez-Hernandez, A., Sommerville, S., Snelling, B., Miller, T. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-182 A multicentric experience for the use of flow diverter in the treatment of anterior communicating artery aneurysms
ConclusionFlow diverters appear to be a safe and effective treatment for anterior communicating artery aneurysms, presenting as an alternative strategy in the armamentarium of interventionalist. Mid-term results were favorable, and complication rates were low. Additional studies with longer follow-up time and independent adjudication are warranted to confirm the safety and effectiveness of the technique.Disclosures V. Benalia: None. G. Cortez: None. N. Kocer: None. C. Islak: None. I. Saatci: None. S. Cekirge: None. F. Baltacıoğlu: None. G. Dabus: None. C. Mounayer: None. A. Siddiqui: None. D. Lopes: None. W. ...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Benalia, V., Cortez, G., Kocer, N., Islak, C., Saatci, I., Cekirge, S., Baltacıoglu, F., Dabus, G., Mounayer, C., Siddiqui, A., Lopes, D., Brinjikji, W., Aghaebrahim, A., Sauvageau, E., Hanel, R. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-187 Pipeline embolization stent for treatment of giant supraclinoid aneurysms: a case series
ConclusionThe Pipeline embolization device is a novel technique that can be utilized for treatment of giant cerebrovascular aneurysms with emerging evidence of immediate and long-term success. Further patient enrollment and clinical trials will be required to assess its efficacy in comparison to other endovascular and surgical approaches for the treatment of giant aneurysms.Disclosures M. Fana: None. O. Alsrouji: None. M. Rehman: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Fana, M., Alsrouji, O., Rehman, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
E-192 Association of myeloperoxidase-DNA complexes and high mobility group box 1 protein with delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage
High mobility group box 1 protein (HMGB1) serves as a key player in aseptic inflammation. Admission serum HMGB1 has been identified as a biomarker predictive of delayed cerebral ischemia following aneurysmal subarachnoid hemorrhage (aSAH). Released by leucocytes and platelets, HMGB1 induces neutrophils to release condensed chromatin and protein granules, termed neutrophil extracellular traps (NETs). Myeloperoxidase (MPO)-DNA complexes are one major NET biomarker and have been associated with arterial and venous thrombosis formation. The prevalence and role of MPO-DNA in aSAH remains to be determined.A post-hoc analysis of ...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Hendrix, P., Witsch, J., Spalart, V., Martinod, K., Schneider, H., Oertel, J., Geisel, J., Hemmer, S. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
O-066 Actin imparts thrombolysis resistance in acute ischemic stroke clots - gelsolin accelerates TPA mediated thrombolysis
ConclusionActin is one of the major structural components of AIS clots and could be responsible for fibrinolytic resistance. Targeting actin molecules would positively impact improving the outcome of recanalization of LVO-AIS.Abstract O-066 Figure 1Disclosures S. Arul: None. D. Dai: None. O. Mereuta: None. S. Ghozy: None. W. Brinjikji: None. D. Kallmes: None. R. Kadirvel: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Arul, S., Dai, D., Mereuta, O., Ghozy, S., Brinjikji, W., Kallmes, D., Kadirvel, R. Tags: SNIS 19th annual meeting oral abstracts Source Type: research
P-001 Evaluation of cerebrovascular flow parameters relative to guide catheter position during acute ischemic stroke treatment
ConclusionDramatically reduced MCA flow can significantly reduce downstream migration of thrombus during thrombectomy. This study demonstrates that Zoom 88 positioned distal to the PComm achieved similar rates of flow control as balloon guide catheters inflated in the proximal ICA. In all cases, flow compensation within the CoW affected the outflow rates of the ipsilateral and contralateral ACA branches, posterior cerebral arteries, and contralateral MCA.Abstract P-001 Figure 1Disclosures H. Berns: 5; C; Northern Arizona University. O. Fisher: 5; C; Northern Arizona University. B. Fennell: 5; C; Northern Arizona University...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Berns, H., Fisher, O., Fennell, B., Ponugupaty, A., Merritt, W., Ducruet, A., Becker, T. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research
E-236 Comparison of pipeline vs surpass flow diverter: a single center experience
ConclusionsIn our single-center retrospective experience in the last 5 years, the Pipeline and Surpass were comparable except that the Surpass flow diverter cases tended to have a higher baseline aneurysm width compared to Pipeline. However, the procedural outcomes and complication rates were comparable between both groups. Long-term and follow-up data to be evaluated for efficacy outcomes assessment.Disclosures A. Pandhi: None. A. Kashkoush: None. M. Bain: None.
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Pandhi, A., Kashkoush, A., Bain, M. Tags: SNIS 19th annual meeting electronic poster abstracts Source Type: research
P-031 End artery location of thrombus predicts poor neurological outcome despite successful thrombectomy for anterior circulation stroke
ConclusionsDespite similar vascular territories, concurrent occlusion of the MCA and ACA segments results in worse clinical outcomes compared to more proximal ICA occlusion. The likely explanation for fast progression of infarct in the MCA+ACA group is the higher likelihood of end-artery involvement and lower contribution of collateral flow. Reperfusion of both territories; however, does add to the risk of symptomatic post-procedural hemorrhage.Disclosures S. Eshraghi: None. S. Saperian: None. A. Alawieh: None. B. Howard: None. J. Grossberg: None. F. Tong: None. P. Jabbour: None. I. Maier: None. S. Wolfe: None. A. Rai: Non...
Source: Journal of NeuroInterventional Surgery - July 23, 2022 Category: Neurosurgery Authors: Eshraghi, S., Saperian, S., Alawieh, A., Howard, B., Grossberg, J., Tong, F., Jabbour, P., Maier, I., Wolfe, S., Rai, A., Starke, R., Gory, B., Psychogios, M., Shaaban, A., Arthur, A., Kim, J., Yoshimura, S., Kan, P., DeLeacy, R., Fragata, I., Polifka, A. Tags: SNIS 19th annual meeting oral poster abstracts Source Type: research
