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Condition: Thrombosis
Drug: Medroxyprogesterone
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Total 16 results found since Jan 2013.
Comparison of Thromboembolism Outcomes in Patients with Sickle Cell Disease Prescribed Hormonal Contraception
This study aims to assess patterns of hormonal contraceptive use and compare risk of contraception-related TE between combined hormonal contraceptives (CHC) and progestin-only contraceptives (POC). Patients with SCD between 12-44 years with a new prescription of a hormonal contraceptive in the CMS MAX database (2006-2018) were followed for one year. Cox regression analysis was used to calculate the hazard ratio (HR) of TE. We identified 7,173 new users: 44.6% initiated CHC and 55.4% initiated POC. Combined oral contraceptive pills (OCP) (36.5%) and progestin-only depot medroxyprogesterone acetate (33.9%) were the most freq...
Source: Adv Data - August 16, 2023 Category: Epidemiology Authors: Natasha S Bala Joseph R Stanek Sara K Vesely Robert M Cronin Susan E Creary Andrea H Roe Wendy Xu Sarah H O'Brien Source Type: research
Pulmonary embolism in menopausal hormone therapy: a population-based register study
CONCLUSION: PE was most common close to initiation of oral treatment. Transdermal MHT did not increase the risk of PE.PMID:36218141 | DOI:10.1080/13697137.2022.2127352
Source: Climacteric - October 11, 2022 Category: Geriatrics Authors: Micaela Sundell Anna-Clara Spetz Holm Mats Fredrikson Mats Hammar Mikael Hoffmann Jan Brynhildsen Source Type: research
Association of Progestogens and Venous Thromboembolism Among Women of Reproductive Age
CONCLUSION: Among reproductive-aged women using one of seven progestogens, only use of norethindrone acetate and medroxyprogesterone acetate-considered higher-dose progestogens-was significantly associated with increased odds of incident acute VTE. The roles of progestogen type, dose, and indication for use warrant further study.PMID:35926206 | DOI:10.1097/AOG.0000000000004896
Source: Obstetrics and Gynecology - August 4, 2022 Category: OBGYN Authors: Richard H Cockrum Jackie Soo Sandra A Ham Kenneth S Cohen Shari G Snow Source Type: research
Menstruation, anticoagulation, and contraception: VTE and uterine bleeding
Res Pract Thromb Haemost. 2021 Aug 1;5(5):e12570. doi: 10.1002/rth2.12570. eCollection 2021 Jul.ABSTRACTAbnormal or excessive menstrual bleeding affects one-third of reproductive-aged women. This number increases to 70% among women on direct oral anticoagulants (DOACs). While there is some variation in frequency of heavy menstrual bleeding (HMB) with different DOAC options, all menstruating individuals should receive counseling about the risk of HMB at the time of DOAC initiation. Management options include progestin-only therapies such as the levonorgestrel intrauterine system and etonogestrel subdermal implant or the pro...
Source: Thrombosis and Haemostasis - August 9, 2021 Category: Hematology Authors: Bethany Samuelson Bannow Claire McLintock Paula James Source Type: research
