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Specialty: Endocrinology
Condition: Stroke

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Total 2154 results found since Jan 2013.

High prevalence of non-alcoholic fatty liver disease in patients with a first episode of acute ischemic stroke. Impact on disability and death
ConclusionPresence of NAFLD did not impact on disability and death after the stroke. However, patients with a first episode of stroke showed a high prevalence of NAFLD, especially at intermediate ages, and therefore, screening for NAFLD should be advisable.
Source: Frontiers in Endocrinology - December 16, 2022 Category: Endocrinology Source Type: research

Insulin resistance in ischemic stroke: Mechanisms and therapeutic approaches
The pathological condition of insulin resistance prevents the neuroprotective effects of insulin. Numerous studies have demonstrated that insulin resistance, as an independent risk factor for ischemic stroke, accelerates the formation of thrombosis and promotes the development of atherosclerosis, both of which are major mechanisms of ischemic stroke. Additionally, insulin resistance negatively affects the prognosis of patients with ischemic stroke regardless of whether the patient has diabetes, but the mechanisms are not well studied. We explored the association between insulin resistance and the primary mechanisms of brai...
Source: Frontiers in Endocrinology - December 15, 2022 Category: Endocrinology Source Type: research

Body mass index has a non-linear association with three-month outcomes in men with acute ischemic stroke: An analysis based on data from a prospective cohort study
ConclusionA particular non-linear connection and saturation effect between BMI (kg/m2) and 3-month unfavorable outcomes were present in male patients with AIS but not in females. 23.35 kg/m2 was the BMI’s inflection point. The probability of unfavorable outcomes was substantially and inversely associated with BMI in men with AIS when it was less than 23.35 kg/m2. Men with AIS should have a BMI of no less than 23.35 kg/m2 to reduce the probability of unfavorable outcomes following AIS.
Source: Frontiers in Endocrinology - December 12, 2022 Category: Endocrinology Source Type: research

Treatment of the New Era: Long-Term Ticagrelor Monotherapy for the Treatment of Patients with Type 2 Diabetes Mellitus following Percutaneous Coronary Intervention: A Meta-analysis
ConclusionLong-term ticagrelor monotherapy after a short course of DAPT use showed better results in patients with T2DM following PCI. Therefore, ticagrelor monotherapy after a short course of DAPT use could be considered an evolution in antiplatelet therapy of this decade for the treatment of patients with T2DM after PCI. However, newer studies with a larger population size and cost-effectiveness are factors that should further be considered.
Source: Diabetes Therapy - December 9, 2022 Category: Endocrinology Source Type: research

Risk of stroke and retinopathy during GLP-1 receptor agonist cardiovascular outcome trials: An eight RCTs meta-analysis
ConclusionGLP-1RA significantly reduces the risk of ischemic stroke in type 2 diabetics with cardiovascular risk factors.
Source: Frontiers in Endocrinology - December 5, 2022 Category: Endocrinology Source Type: research

Relationship of the metabolic score for insulin resistance and the risk of stroke in patients with hypertension: A cohort study
ConclusionsThis cohort study suggests a relationship between METS-IR and the risk of stroke and ischemic stroke. Further studies are required to elucidate the underlying mechanisms.
Source: Frontiers in Endocrinology - December 5, 2022 Category: Endocrinology Source Type: research

Hypertriglyceridemic waist phenotype: Association with initial neurological severity and etiologic subtypes in patients with acute ischemic stroke
ConclusionInitial neurological severity was less severe in patients with HTWP, and HTWP was associated with an increased risk of small-artery occlusion stroke.
Source: Frontiers in Endocrinology - December 1, 2022 Category: Endocrinology Source Type: research

Hypertriglyceridemia may contribute to stroke and pancreatitis: A case report and review of the literature
We present a case of hypertriglyceridemia-associated stroke and pancreatitis in a 39-year-old woman. The patient’s laboratory tests reported high triglyceride concentrations beyond the instrument’s detection range, and radiological examination showed typical signs of cerebral infarction and acute pancreatitis. The patient received combined blood purification therapy, intravenous thrombolysis with urokinase, and conservative treatment of pancreatitis. We discuss the clinical features, pathogenesis, diagnosis, and treatment of hypertriglyceridemic stroke and pancreatitis combined with the relevant literature. We reviewed...
Source: Frontiers in Endocrinology - December 1, 2022 Category: Endocrinology Source Type: research

Utilization of screening and treatment for osteoporosis among stroke survivors
ConclusionsBoth BMD testing and osteoporosis treatment were underutilized among stroke survivors even though they had a higher chance of receiving both measures than non-stroke patients.
Source: Frontiers in Endocrinology - December 1, 2022 Category: Endocrinology Source Type: research

Clinical significance of skin autofluorescence for diabetic macroangiopathy and comparison with conventional markers of atherosclerosis: a cross-sectional and prospective study
ConclusionAmong diabetic macroangiopathies, SAF is a good stroke biomarker, but not for CAD and PAD.
Source: Diabetology International - November 28, 2022 Category: Endocrinology Source Type: research

Correlation of Triglyceride-Rich Lipoprotein Cholesterol and Diabetes Mellitus in Stroke Patients
CONCLUSION: Positive associations were found between TRL-c and DM in patients with stroke.PMID:36389128 | PMC:PMC9652082 | DOI:10.1155/2022/7506767
Source: International Journal of Endocrinology - November 17, 2022 Category: Endocrinology Authors: Ruiqing Luo Huifang Jiang Tao Wang Yanfang Xu Xueliang Qi Source Type: research

Out-of-Hospital Cold Water Immersion for Classic (Non-Exertional) Heat Stroke Guided by Real-time Core Temperature Monitoring: A Case Series
Prehosp Emerg Care. 2022 Nov 15:1-11. doi: 10.1080/10903127.2022.2148795. Online ahead of print.ABSTRACTHeat stroke is a problem that occurs primarily in the out-of-hospital environment. "Cool first, transport second" has been emphasized in consensus statements and systematic reviews regarding the treatment of exertional heat stroke by both EMS and the sports medicine/athletic training communities. However, there remains little guidance on cooling recommendations for the out-of-hospital care of non-exertional heat stroke or classic heat stroke. There is no consensus on the safety or feasibility of cooling classic heat stro...
Source: Prehospital Emergency Care - November 15, 2022 Category: Endocrinology Authors: Ryan C Jacobsen Bryan Beaver Benjamin Abo Source Type: research