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Condition: Stroke
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Total 633 results found since Jan 2013.
The unexpected benefits of sodium glucose co-transporter 2 (SGLT2) Inhibitors
N Z Med J. 2022 Aug 19;135(1560):99-104.ABSTRACTThe sodium glucose co-transporter 2 (SGLT2) inhibitor empagliflozin is currently funded in New Zealand for management of patients with type 2 diabetes who have an HbA1c >53mmol/mol and a high cardiovascular (CV) risk. Large clinical trials now provide strong evidence that SGLT2 inhibitors decrease the risk of cardiovascular death, heart failure, progressive kidney dysfunction, myocardial infarction, stroke and gout. Patients with or without diabetes who have a history of heart failure, including those with a preserved left ventricular ejection fraction and patients with ch...
Source: New Zealand Medical Journal - August 24, 2022 Category: General Medicine Authors: Chok G Chan Ralph Stewart Source Type: research
Plasma epoxyeicosatrienoic acids and diabetes-related cardiovascular disease: The cardiovascular health study
EBioMedicine. 2022 Aug 2;83:104189. doi: 10.1016/j.ebiom.2022.104189. Online ahead of print.ABSTRACTBACKGROUND: Epoxyeicosatrienoic acids (EETs) are metabolites of arachidonic acid that may impact atherosclerosis, and animal experimental studies suggest EETs protect cardiac function. Plasma EETs are mostly esterified to phospholipids and part of an active pool. To address the limited information about EETs and CVD in humans, we conducted a prospective study of total plasma EETs (free + esterified) and diabetes-related CVD in the Cardiovascular Health Study (CHS).METHODS: We measured 4 EET species and their metabolites, dih...
Source: Atherosclerosis - August 5, 2022 Category: Cardiology Authors: Rozenn N Lemaitre Paul N Jensen Maxwell Zeigler Amanda M Fretts Jason G Umans Barbara V Howard Colleen M Sitlani Barbara McKnight Sina A Gharib Irena B King David S Siscovick Bruce M Psaty Nona Sotoodehnia Rheem A Totah Source Type: research
Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study
Lancet Public Health. 2022 Aug 1:S2468-2667(22)00110-4. doi: 10.1016/S2468-2667(22)00110-4. Online ahead of print.ABSTRACTBACKGROUND: The improvement of life expectancy is one of the aims of the Healthy China 2030 blueprint. We aimed to investigate the extent to which healthy lifestyles are associated with life expectancy in Chinese adults.METHODS: We used the prospective China Kadoorie Biobank (CKB) study to examine the relative risk of mortality associated with individual and combined lifestyle factors (never smoking or quitting not for illness, no excessive alcohol use, being physically active, healthy eating habits, an...
Source: Cancer Control - August 4, 2022 Category: Cancer & Oncology Authors: Qiufen Sun Dongmei Yu Junning Fan Canqing Yu Yu Guo Pei Pei Ling Yang Yiping Chen Huaidong Du Xiaoming Yang Sam Sansome Yongming Wang Wenhua Zhao Junshi Chen Zhengming Chen Liyun Zhao Jun Lv Liming Li China Kadoorie Biobank Collaborative Group Source Type: research
Dartmouth ’s Supattapone Receives Prestigious Javits Neuroscience Investigator Award
Surachai Supattapone, MD, PhD, a professor of biochemistry and cell biology and of medicine at Dartmouth’s Geisel School of Medicine, has received a Javits Neuroscience Investigator Award from the National Institute of Neurological Disorders and Stroke. The prestigious $4.9 million award will provide up to seven years of funding for his research on prions—infectious agents that cause fatal neurogenerative diseases.
Source: News at Dartmouth Medical School - August 3, 2022 Category: Hospital Management Authors: Timothy Dean Tags: Education News Javits Neuroscience Investigator Award Surachai Supattapone Source Type: news
Risk of future cardiovascular diseases in different years postpartum after hypertensive disorders of pregnancy: A systematic review and meta-analysis
Discussion:
A history of HDP is associated with approximately 2- to 4-fold increase in the risk of CVDs. Screening for CVDs and their risk factors in women with prior HDP since delivery, especially the first 5 years after delivery is suggested for early detection and appropriate management. Evidence on the risks of CVDs in preeclampsia with severe features and early onset of preeclampsia is limited due to having few studies and high heterogeneity.
Funding:
The Royal Golden Jubilee PhD Program–RGJ (PHD/0183/2561); Thailand Science Research and Innovation (TSRI) Research Career Development Grant–RSA (RSA618000...
Source: Medicine - July 29, 2022 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research
Post-stroke Sexual Dysfunction in Men: Epidemiology, Diagnostic Work-up, and Treatment
by Rocco Salvatore Calabrò, MD, PhD Dr. Calabrò is with IRCCS Centro Neurolesi “Bonino-Pulejo” in Messina, Italy. Funding: No funding was provided for this article. Disclosures: The author has no conflicts of interest relevant to the content of this article. Innov Clin Neurosci. 2022;19(7–9):12–16. Abstract Stroke is a leading cause of death and disability throughout […]
The post Post-stroke Sexual Dysfunction in Men: Epidemiology, Diagnostic Work-up, and Treatment appeared first on Innovations in Clinical Neuroscience.
Source: Innovations in Clinical Neuroscience - July 1, 2022 Category: Neuroscience Authors: ICNS Online Editor Tags: Commentary Current Issue Neurology counseling sexual coach sexuality stroke Source Type: research
NIH ’s vaunted program for solving puzzling medical cases is running out of money
Ten years ago, an athletic 12-year-old from Affton, Missouri, named Mitchell Herndon began to experience muscle weakness that eventually led to him using a wheelchair. After years of visits to specialists failed to diagnose his neurological symptoms, he enrolled in a National Institutes of Health (NIH)-funded program that studies patients with debilitating mystery diseases. Researchers eventually found an explanation for Mitchell’s condition: a mutated gene that causes certain brain cells to produce an overactive protein that leads to neuron damage.
Mitchell died 3 years ago at age 19. Since then, 14 more people hav...
Source: Science of Aging Knowledge Environment - June 27, 2022 Category: Geriatrics Source Type: research
