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Condition: Pneumonia
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Total 107 results found since Jan 2013.
Knockdown of EPSTI1 alleviates lipopolysaccharide-induced inflammatory injury through regulation of NF- κB signaling in a cellular pneumonia model
CONCLUSIONS: These results provided promising management in preventing pneumonia in patients.PMID:35527663 | DOI:10.15586/aei.v50i3.581
Source: Allergologia et Immunopathologia - May 9, 2022 Category: Allergy & Immunology Authors: Adilijiang Kari Zhihua M Zhayidan Aili Ayinuerguli Adili Nadire Hairula Abulaiti Abuduhaer Source Type: research
Mycoplasma hyopneumoniae Infection Activates the NOD1 Signaling Pathway to Modulate Inflammation
This study revealed that M. hyopneumoniae activates the NOD1-RIP2 pathway and is co-localized with host NOD1 during infection. siRNA knockdown of NOD1 significantly impaired the TRIF and MYD88 pathway and blocked the activation of TNF-α. In contrast, NOD1 overexpression significantly suppressed M. hyopneumoniae proliferation. Furthermore, we for the first time investigated the interaction between M. hyopneumoniae mhp390 and NOD1 receptor, and the results suggested that mhp390 and NOD1 are possibly involved in the recognition of M. hyopneumoniae. These findings may improve our understanding of the interaction between PRRs ...
Source: Frontiers in cellular and infection microbiology - July 8, 2022 Category: Microbiology Source Type: research
Molecular cloning, prokaryotic expression and the anti-inflammatory activity of porcine PRDX5
In this study, the full-length cDNA encoding porcine PRDX5 (pPRDX5) was cloned. Subsequently, using porcine alveolar macrophages (PAMs), the target cells of PRRSV infection in vivo, we found that the recombinant pPRDX5 protein inhibited inflammatory responses induced by tumor necrosis factor alpha (TNF-α) or porcine reproductive and respiratory syndrome virus (PRRSV), a virus causing severe interstitial pneumonia in pigs. By contrast, knockdown of endogenous pPRDX5 with specific siRNA enhanced inflammatory responses induced by TNF-α or PRRSV. We also demonstrated that the involvement of pPRDX5 in inflammation regulation ...
Source: Developmental and Comparative Immunology - August 19, 2022 Category: Allergy & Immunology Authors: Panpan Ma Yanrong Zhou Puxian Fang Wenting Ke Shaobo Xiao Liurong Fang Source Type: research
Abstracts of Presentations at the Association of Clinical Scientists 143 < sup > rd < /sup > Meeting Louisville, KY May 11-14,2022
Conclusion: These assays are suitable for routine diagnostic. The UltraFast NextGenPCR is the fastest with average time (30mins), followed by Agilent (2 hrs) and MassArray (6hrs). Upon completion of this activity, participants should be able to examine, measure and compare results from different assays for SARS detection, evaluate and diagnose accurately, as well as being able to plan, organize and recommend a diagnostic procedure for diagnostic laboratory. Key words: SARS-CoV-2, RNA extraction, RT-PCR, limit of detection, quantification cycle, COVID-19, in vitro diagnostic tests, Agilent, Massarray, Ultrafast. [20] From t...
Source: Annals of Clinical and Laboratory Science - July 1, 2022 Category: Laboratory Medicine Source Type: research
