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Condition: Pain
Vaccination: Varicella-Zoster Virus Vaccine

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Total 82 results found since Jan 2013.

Herpes zoster: A Review of Clinical Manifestations and Management
The objective of this review is to discuss current updates related to clinical presentations, complications, and management of HZ.PMID:35215786 | PMC:PMC8876683 | DOI:10.3390/v14020192
Source: Herpes - February 26, 2022 Category: Infectious Diseases Authors: Anant Patil Mohamad Goldust Uwe Wollina Source Type: research

Healing of Severe Herpes Zoster Ophthalmicus Within a Few Days: An Autobiographical Case Report
Cureus. 2021 Dec 9;13(12):e20303. doi: 10.7759/cureus.20303. eCollection 2021 Dec.ABSTRACTHerpes zoster (shingles) is caused by the herpes zoster virus and is characterized by pain and unilateral vesicular rash that typically affects one dermatome. Symptoms tend to resolve over 10-15 days. This case report describes the 75-year-old author's herpes zoster ophthalmicus (HZO) accompanied by severe orbital edema. The upper eyelid and the proximal nasal area were also affected. The author felt an intermittent throbbing pain in more than three dermatomes including the frontal, orbital, temporal, and occipital/nuchal areas. Since...
Source: Herpes - January 13, 2022 Category: Infectious Diseases Authors: Tibor Bakacs Source Type: research

Safety and reactogenicity of the adjuvanted recombinant zoster vaccine: experience from clinical trials and post-marketing surveillance
Ther Adv Vaccines Immunother. 2021 Nov 30;9:25151355211057479. doi: 10.1177/25151355211057479. eCollection 2021.ABSTRACTAn adjuvanted recombinant zoster vaccine (RZV) is licensed for the prevention of herpes zoster. This paper reviews its safety and reactogenicity. A pooled analysis of two pivotal randomized Phase-3 trials (NCT01165177, NCT01165229) in adults ?50 years found that more solicited adverse events (AEs) were reported with RZV than placebo. Injection site pain was the most common solicited AE (RZV: 78.0% participants; placebo: 10.9%). Grade-3 pain occurred in 6.4% of RZV and 0.3% of placebo recipients. Myalgia, ...
Source: Herpes - January 10, 2022 Category: Infectious Diseases Authors: Joseph Fiore Maribel Miranda Co-van der Mee Andr és Maldonado Lisa Glasser Phil Watson Source Type: research

Reactivation of varicella zoster infection presenting as acute retinal necrosis post COVID 19 vaccination in an Asian Indian male
CONCLUSION AND SIGNIFICANCE: To the best of our knowledge this is the earliest description of a case that has a viral reactivation following COVID-19 vaccination. Elderly people with pre-existing comorbidities, may be at a risk of both primary coronavirus infection and unconceivable risk of aberrant immune reactions leading to a different virus infection or reactivation need to be kept in mind. We present a possible link between SARS-CoV-2 virus vaccination and varicella zoster reactivation in this patient.PMID:34541931 | DOI:10.1177/11206721211046485
Source: European Journal of Ophthalmology - September 20, 2021 Category: Opthalmology Authors: Sai Bhakti Mishra Padmamalini Mahendradas Ankush Kawali Srinivasan Sanjay Rohit Shetty Source Type: research

Locked-nucleotide antagonists to varicella zoster virus small non-coding RNA block viral growth and have potential as an anti-viral therapy
Antiviral Res. 2021 Jul 22:105144. doi: 10.1016/j.antiviral.2021.105144. Online ahead of print.ABSTRACTHerpes zoster (HZ) remains a significant health burden with millions of cases in North America and Europe annually. HZ is frequently followed by long-term pain or post-herpetic neuralgia (PHN). Although effective vaccines for HZ are available, currently used nucleotide analogues are often have limited effectiveness against HZ and especially PHN, so there remains a need for additional antiviral therapies for HZ. We recently identified a population of small non-coding RNA (sncRNA) encoded by Varicella Zoster Virus (VZV) and...
Source: Antiviral Research - July 25, 2021 Category: Virology Authors: Biswajit Das Punam Bisht Paul R Kinchington Ronald S Goldstein Source Type: research

A rare case of shingles after COVID-19 vaccine: is it a possible adverse effect?
Clin Exp Vaccine Res. 2021 May;10(2):198-201. doi: 10.7774/cevr.2021.10.2.198. Epub 2021 May 31.ABSTRACTCoronavirus disease 2019 (COVID-19) exhibit mild to moderate symptoms, whereas 15% of COVID-19 cases progress to pneumonia, some associated cutaneous findings are also reported as maculopapular eruptions, morbilliform rashes, urticaria, chickenpox-like lesions, and livedo reticularis. The inactivated COVID-19 vaccines are authorized for use in some countries including Turkey. Here, we report an unusual case of varicella-zoster virus (VZV) reactivation in a 68-year-old male patient who was vaccinated against COVID-19. The...
Source: Cell Research - July 5, 2021 Category: Cytology Authors: Saliha Bu şra Aksu G üzin Zeren Öztürk Source Type: research