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Vaccination: Vaccines

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Total 1735 results found since Jan 2013.

Therapeutics for treating mpox in humans
CONCLUSIONS: Randomized controlled trials review This review found no evidence from randomized controlled trials concerning the efficacy and safety of therapeutics in humans with mpox. Non-randomized studies review Very low-certainty evidence from non-randomized studies indicates no serious safety signals emerging for the use of tecovirimat in people with mpox infection. In contrast, very low-certainty evidence raises a safety signal that brincidofovir may cause liver injury. This is also suggested by indirect evidence from brincidofovir use in smallpox. This warrants further investigation and monitoring. This Cochrane Rev...
Source: Cochrane Database of Systematic Reviews - March 14, 2023 Category: General Medicine Authors: Tilly Fox Susan Gould Naveena Princy Tim Rowland Vittoria Lutje Rebecca Kuehn Source Type: research

Detection of Sporadic Outbreaks of Rift Valley Fever in Uganda through the National Viral Hemorrhagic Fever Surveillance System, 2017-2020
We report 52 human cases of laboratory-confirmed RVF from 2017 to 2020. The case fatality rate was 42%. Among those infected, 92% were males and 90% were adults (≥ 18 years). Clinical symptoms were characterized by fever (69%), unexplained bleeding (69%), headache (51%), abdominal pain (49%), and nausea and vomiting (46%). Most of the cases (95%) originated from central and western districts that are part of the cattle corridor of Uganda, where the main risk factor was direct contact with livestock (P = 0.009). Other predictors of RVF positivity were determined to be male gender (P = 0.001) and being a butcher (P = 0.04)...
Source: Am J Trop Med Hyg - March 13, 2023 Category: Infectious Diseases Authors: Luke Nyakarahuka Shannon Whitmer John Klena Stephen Balinandi Emir Talundzic Alex Tumusiime Jackson Kyondo Sophia Mulei Ketan Patel Jimmy Baluku Gloria Akurut Diana Namanya Kilama Kamugisha Caitlin Cossaboom Amy Whitesell Carson Telford James Graziano Joe Source Type: research

Pattern of self-reported adverse events related to COVID-19 vaccines in Saudi Arabia: A nationwide study
CONCLUSION: This study demonstrated that the most prevalent SARS-CoV-2 vaccine side-effects among adults in Saudi Arabia were mild in nature. This information will help reduce vaccine hesitancy and encourage further mass vaccination to combat the COVID-19 pandemic, especially as booster doses are now available. Further studies are warranted to obtain a better understanding of the association between risk factors and the experiencing of side-effects post vaccination.PMID:36908451 | PMC:PMC9995884 | DOI:10.3389/fpubh.2023.1043696
Source: Atherosclerosis - March 13, 2023 Category: Cardiology Authors: Joud Mohammed Alkhalifah Ahad Al Seraihi Jaffar A Al-Tawfiq Badr Fadhel Alshehri Alhanouf Hani Alhaluli Naif Mansour Alsulais Mohammed Mesfer Alessa Waleed Seddiq Thamer Aljeri Mohammad Hassan Qahtani Mazin Barry Maram Al-Otaiby Source Type: research

Detection of Sporadic Outbreaks of Rift Valley Fever in Uganda through the National Viral Hemorrhagic Fever Surveillance System, 2017-2020
We report 52 human cases of laboratory-confirmed RVF from 2017 to 2020. The case fatality rate was 42%. Among those infected, 92% were males and 90% were adults (≥ 18 years). Clinical symptoms were characterized by fever (69%), unexplained bleeding (69%), headache (51%), abdominal pain (49%), and nausea and vomiting (46%). Most of the cases (95%) originated from central and western districts that are part of the cattle corridor of Uganda, where the main risk factor was direct contact with livestock (P = 0.009). Other predictors of RVF positivity were determined to be male gender (P = 0.001) and being a butcher (P = 0.04)...
Source: Am J Trop Med Hyg - March 13, 2023 Category: Infectious Diseases Authors: Luke Nyakarahuka Shannon Whitmer John Klena Stephen Balinandi Emir Talundzic Alex Tumusiime Jackson Kyondo Sophia Mulei Ketan Patel Jimmy Baluku Gloria Akurut Diana Namanya Kilama Kamugisha Caitlin Cossaboom Amy Whitesell Carson Telford James Graziano Joe Source Type: research

Improving Vaccination Rates in the Clinical Setting
Pediatr Ann. 2023 Mar;52(3):e89-e95. doi: 10.3928/19382359-20230119-02. Epub 2023 Mar 1.ABSTRACTPediatric providers can consider using the 5 P's paradigm for process improvement to optimize vaccination rates in the clinical settings: People, Processes, Pharmacy principles, Pain prevention, and Presumptive vaccine communications. Maintaining high clinical setting vaccination rates requires hiring and training the right people with vaccination details for the population being served, perfecting safe vaccine delivery processes including when and where to vaccinate, using pharmacy principles for proper vaccine storage and hand...
Source: Pediatric Annals - March 7, 2023 Category: Pediatrics Authors: Patricia Stinchfield Kristine Almeida Source Type: research