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Total 161 results found since Jan 2013.

Automatic Classification of the Korean Triage Acuity Scale in Simulated Emergency Rooms Using Speech Recognition and Natural Language Processing: a Proof of Concept Study
CONCLUSION: We demonstrated the potential of an automatic KTAS classification system using speech recognition models, machine learning and BERT-based classifiers.PMID:34254471 | DOI:10.3346/jkms.2021.36.e175
Source: Journal of Korean Medical Science - July 13, 2021 Category: Biomedical Science Authors: Dongkyun Kim Jaehoon Oh Heeju Im Myeongseong Yoon Jiwoo Park Joohyun Lee Source Type: research

Janssen Submits New Drug Application to U.S. FDA for XARELTO ® (rivaroxaban) to Help Prevent and Treat Blood Clots in Pediatric Patients
RARITAN, NJ, June 23, 2021 – The Janssen Pharmaceutical Companies of Johnson & Johnson announced today it has submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration (FDA) for the use of XARELTO® (rivaroxaban) in pediatric patients. The NDA seeks two pediatric indications: treatment of venous thromboembolism (VTE, or blood clots) and reduction in the risk of recurrent VTE in patients aged birth to less than 18 years of age after at least five days of initial parenteral anticoagulant treatment; and thromboprophylaxis (prevention of blood clots) in patients aged 2 years and older with congenita...
Source: Johnson and Johnson - June 23, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Behavioral Assessment of Sensory, Motor, Emotion, and Cognition in Rodent Models of Intracerebral Hemorrhage
Intracerebral hemorrhage (ICH) is the second most common type of stroke and has one of the highest fatality rates of any disease. There are many clinical signs and symptoms after ICH due to brain cell injury and network disruption resulted from the rupture of a tiny artery and activation of inflammatory cells, such as motor dysfunction, sensory impairment, cognitive impairment, and emotional disturbance, etc. Thus, researchers have established many tests to evaluate behavioral changes in rodent ICH models, in order to achieve a better understanding and thus improvements in the prognosis for the clinical treatment of stroke...
Source: Frontiers in Neurology - June 17, 2021 Category: Neurology Source Type: research

Headache in Women
PURPOSE OF REVIEW Women are greatly overrepresented among patients seeking treatment for symptoms of headache pain in general and migraine in particular. Understanding the presentation of headache in women in relation to hormonal changes both during the menstrual cycle and throughout the life span is essential for appropriate diagnosis and treatment. RECENT FINDINGS Although perimenstrual migraine attacks are generally without aura, the diagnosis of migraine with aura has been added to the headache classification for menstrual migraine to account for women with the diagnosis of migraine with aura who experience ...
Source: CONTINUUM: Lifelong Learning in Neurology - June 1, 2021 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

GLP-1R activation ameliorated novel-object recognition memory dysfunction via regulating hippocampal AMPK/NF- κB pathway in neuropathic pain mice
Neurobiol Learn Mem. 2021 May 17:107463. doi: 10.1016/j.nlm.2021.107463. Online ahead of print.ABSTRACTGrowing evidences indicate that neuropathic pain is frequently accompanied with cognitive impairments, which aggravate the decrease in the quality of life of chronic pain patients. Furthermore, it has been shown that the activation of Glucagon-like-peptide-1receptor (GLP-1R) improved memory deficit in multiple diseases, including Alzheimer's disease (AD), stroke. However, whether GLP-1R activation could improve memory impairment induced by neuropathic pain and the mechanisms underlying the effect of the activation of GLP-...
Source: Neurobiology of Learning and Memory - May 20, 2021 Category: Neurology Authors: Long-Qing Zhang Wen Zhang Ting Li Ting Yang Xiaoman Yuan Yaqun Zhou Qian Zou Hui Yang Feng Gao YuKe Tian Wei Mei Xue-Bi Tian Source Type: research