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The Transcriptome of the Salivary Glands of Amblyomma aureolatum Reveals the Antimicrobial Peptide Microplusin as an Important Factor for the Tick Protection Against Rickettsia rickettsii Infection
Conclusion In conclusion, our data show that R. rickettsii exerts a modulatory effect on the transcriptional profile the SG of A. aureolatum. Moreover, RNAi experiments demonstrated that the knockdown of one microplusin increases the susceptibility of ticks to infection, suggesting that this is one important factor for the control of R. rickettsii. The functional characterization of the additional CDSs modulated by infection is warranted and might reveal other factors that interfere with the acquisition and/or transmission of this tick-borne pathogen. Ethics Statement All procedures involving vertebrate animals were car...
Source: Frontiers in Physiology - May 2, 2019 Category: Physiology Source Type: research

Assessment of the Probability of Autochthonous Transmission of Chikungunya Virus in Canada under Recent and Projected Climate Change
This study identifies that southern Canada may be the very northern limit for transmission of these pathogens with climate change. Other factors need to be explored however, which include understanding when and where Canadian travelers are likely to return, infrastructure in Canada that may support vector populations in what would be expected to be climatically unsuitable regions, and whether or not there are other competent vectors in Canada. Further research to close the gap on our current understanding of CHIKV and CHIKV vectors, improved surveillance on Ae. albopictus in North America, and enhanced climate projection m...
Source: EHP Research - June 5, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Source Type: research