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Specialty: Respiratory Medicine
Condition: Hypertension
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Total 342 results found since Jan 2013.
Obstructive Sleep Apnoea (OSA): Men vs Women
Conclusion: Women had higher BMIs, ESS and lower AHIs than men. M: F ratio with AHI>15 was 2.54 which shows that fewer women than expected are being referred. Our M: F ratio of 2.10 in over 50’s reflects the known higher incidence of OSA in post-menopausal women, but remains below that expected from population studies. Thus more awareness is needed locally to improve recognition of OSA in our female population.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Haqqee, R., Jordan, T., Allen, M. Tags: Sleep and Control of Breathing Source Type: research
Chronic bronchitis, asthma and rhinitis are differently associated with cardiovascular risk factors and diseases
Conclusions: our preliminary results suggest that 1) chronic respiratory diseases are associated with different cardiovascular risk factors; 2) the associations of CB and rhinitis with cardiovascular diseases seem to be independent of the presence of shared risk factors.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Pesce, G., Marcon, A., Cazzoletti, L., Battaglia, S., Cerveri, I., Pirina, P., Trucco, G., Locatelli, F., Ferrari, M. Tags: Epidemiology Source Type: research
Longitudinal cardiac changes in a SUGEN/Hypoxic Rat Model of Pulmonary Hypertension determined by Cardiac MRI
Conclusion: 5 weeks of SuHx resulted in RV dysfunction and RV hypertrophy. Although RV systolic pressure remained elevated throughout the 8 week study period, RV dysfunction and RV hypertrophy had improved demonstrating adaptive remodelling of the SuHx rat RV to the induced persistent PH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Jayasekera, G., Wilson, K., Buist, H., Hughes, C., Nilsen, M., Church, C., Gallagher, L., Mullin, J., Maclean, M., Holmes, W., Welsh, D., Peacock, A. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
Haemodynamic effects of exercise therapy in stable, optimally treated pulmonary arterial hypertension
Conclusions: Provisional results suggest exercise therapy in PAH has a positive effect on the pressure-flow relationship in the pulmonary circulation, leading to reduced stress on the right ventricle on exertion. This change may improve long term outcomes.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: MacKenzie, A., Ford, J., Jayasekera, G., Crowe, T., Peacock, A., Church, C., Johnson, M. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
Right ventricular contractile reserve and pulmonary arterial compliance differentiate PAH patients with long-term survival and therapeutic success
Conclusions: RV contractile reserve and PA compliance differentiates long-term survivors (>10 years of treatment) from short-term survivors (<2 years of treatment) on PAH specific therapy.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Vanderpool, R., Wickstrom, K., Desai, A., Nair, V., Bernardo, R., Rischard, F. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
The effect of 6-mercaptopurine treatment on experimentally induced pulmonary arterial hypertension
Conclusion: 6-MP partly reversed RV systolic pressure and RV afterload in established PAH. Together with the observed improved RV remodeling and cardiac function, 6-MP may be a promising intervention for PAH.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Sun, X.-Q., Kurakula, K., Happe, C., da Silva Goncalves Bos, D., Schalij, I., Vonk-Noordegraaf, A., de Man, F. S., Bogaard, H.-J., Goumans, M.-J. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
Altered synchrony of right ventricular contraction inborderline pulmonary hypertension
Conclusion: RV dyssynchrony occurs in borderline PH and may reflect early RV arterial uncoupling.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Lamia, B., Muir, J.-F., Molano, L.-C., Viacroze, C., Bonnet, P., Quieffin, J., Benichou, J., Cuvelier, A., Naeije, R. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
Validation of cardiac MR parameters in the assessment of pulmonary hemodynamics
Conclusions: In our prospective cohort, the literature-based formulas for calculation of PAP and PVR based on CMR-based measures could largely be validated. The best correlations were derived from multiparametric formulas including right ventricular ejection fraction.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Odler, B., Reiter, U., Reiter, G., Fuchsjäger, M., Foris, V., Tornyos, A., Douschan, P., Pfeiffer, S., Olschewski, A., Olschewski, H., Kovacs, G. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
Cardiovascular events and mortality in CPAP adherent OSAS patients - a 9-year retrospective study
Conclusions: High adherence to CPAP treatment protected OSAS patients against primary and secondary ischemic cardiovascular events and deaths.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Myllylä, M., Hammais, A., Stepanov, M., Anttalainen, U., Saaresranta, T., Laitinen, T. Tags: Sleep and Control of Breathing Source Type: research
Effect of riociguat on pulmonary arterial compliance in patients with pulmonary arterial hypertension (PAH) in the RESPITE study
Conclusion: In RESPITE, riociguat improved PAC in patients with PAH who had transitioned from PDE5i. The increase in PAC was more pronounced in patients whose exercise and functional capacity had also improved by Week 24.
Source: European Respiratory Journal - December 6, 2017 Category: Respiratory Medicine Authors: Hoeper, M. M., Corris, P. A., Ghofrani, H.-A., Klinger, J. R., Langleben, D., Naeije, R., Simonneau, G., Jansa, P., Rosenkranz, S., Grünig, E., Scelsi, L., Meier, C., Busse, D., Benza, R. L. Tags: Pulmonary Circulation and Pulmonary Vascular Disease Source Type: research
2004 to 2014 Saw Increases in Risk Factors in Ischemic Stroke
Increases in prevalence of hypertension, diabetes, dyslipidemia, smoking, and drug abuse in AIS
Source: Pulmonary Medicine News - Doctors Lounge - October 12, 2017 Category: Respiratory Medicine Tags: Cardiology, Family Medicine, Geriatrics, Gynecology, Internal Medicine, Emergency Medicine, Neurology, Nursing, Pathology, Pulmonology, Journal, Source Type: news
Management of hypertension in obstructive sleep apnoea: predicting blood pressure reduction under continuous positive airway pressure
Hypertension affects a quarter of the adult population and remains a leading cause of cardiovascular mortality, accounting for 13.5% of all deaths. Half of all strokes and ischaemic heart disease events are attributable to high blood pressure (BP) [1, 2]. Most patients exhibit Grade-I hypertension (systolic BP of 140 to 159 mmHg and/or diastolic BP of 90 to 99 mmHg) without co-existing cardiovascular disease. An active reduction of BP results in a significant reduction in stroke and death [3].
Source: European Respiratory Journal - October 5, 2017 Category: Respiratory Medicine Authors: Tamisier, R., Levy, P. Tags: Sleep medicine Editorial Source Type: research
Features and Outcomes of Methamphetamine Associated Pulmonary Arterial Hypertension.
CONCLUSIONS: Meth-APAH is a severe and progressive form of PAH with poor outcomes. Future studies should focus on mechanisms of disease and potential therapeutic considerations.
PMID: 28934596 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 21, 2017 Category: Respiratory Medicine Authors: Zamanian RT, Hedlin H, Greuenwald P, Wilson DM, Segal JI, Jorden M, Kudelko K, Liu J, Hsi A, Rupp A, Sweatt AJ, Tuder R, Berry GJ, Rabinovitch M, Doyle RL, De Jesus Perez V, Kawut SM Tags: Am J Respir Crit Care Med Source Type: research
Severe obstructive sleep apnea is associated with cochlear function impairment
ConclusionsAcoustic transference function of middle ear is similar in adults with and without OSA. Severe OSA is independently associated with cochlear function impairment in patients with no significant co-morbidities.
Source: Sleep and Breathing - July 5, 2017 Category: Respiratory Medicine Source Type: research
Do patients with obstructive sleep apnoea deserve new dedicated antihypertensive strategies?
Hypertension affects 25% of the adult population and remains a leading cause of cardiovascular mortality, accounting for 13.5% of all deaths. Half of all strokes and ischaemic heart disease events are attributed to hypertension.1 2 Most patients exhibit grade I hypertension (systolic blood pressure of 140–159 mm Hg and/or diastolic blood pressure of 90–99 mm Hg) without coexisting cardiovascular disease. Effective reduction of blood pressure in this population significantly reduces stroke and death.3 Obstructive sleep apnoea (OSA) is now recognised as a risk factor for the development of hyp...
Source: Thorax - May 15, 2017 Category: Respiratory Medicine Authors: Tamisier, R., Levy, P., Pepin, J.-L. Tags: Editorial Source Type: research
