• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Urinary Sodium and Potassium, and Risk of Ischaemic and Haemorrhagic Stroke (INTERSTROKE): a case-control study.
CONCLUSION: The association of sodium intake and stroke is J-shaped, with high sodium intake a stronger risk factor for intracerebral haemorrhage than ischemic stroke. Our data suggest that moderate sodium intake - rather than low sodium intake - combined with high potassium intake may be associated with the lowest risk of stroke and expected to be a more feasible combined dietary target. PMID: 33197265 [PubMed - as supplied by publisher]
Source: American Journal of Hypertension - November 17, 2020 Category: Cardiology Authors: Judge C, O'Donnell MJ, Hankey GJ, Rangarajan S, Chin SL, Rao-Melacini P, Ferguson J, Smyth A, Xavier D, Lisheng L, Zhang H, Lopez-Jaramillo P, Damasceno A, Langhorne P, Rosengren A, Dans AL, Elsayed A, Avezum A, Mondo C, Ryglewicz D, Czlonkowska A, Pogoso Tags: Am J Hypertens Source Type: research

Cost-effectiveness of a Household Salt Substitution Intervention: Findings From 20,995 Participants of the Salt Substitute and Stroke Study (SSaSS)
Conclusions: Replacing regular salt with salt substitute was a cost-saving intervention for the prevention of stroke and improvement of quality of life amongst the SSaSS participants.PMID:35311346 | DOI:10.1161/CIRCULATIONAHA.122.059573
Source: Circulation - March 21, 2022 Category: Cardiology Authors: Ka-Chun Li Liping Huang Maoyi Tian Gian Luca Di Tanna Jie Yu Xinyi Zhang Xuejun Yin Yishu Liu Zhixin Hao Bo Zhou Xiangxian Feng Zhifang Li Jianxin Zhang Jixin Sun Yuhong Zhang Yi Zhao Ruijuan Zhang Yan Yu Nicole Li Lijing L Yan Darwin R Labarthe Paul Elli Source Type: research

Dietary potassium: A key mediator of the cardiovascular response to dietary sodium chloride
Abstract: Potassium and sodium share a yin/yang relationship in the regulation of blood pressure (BP). BP is directly associated with the total body sodium and negatively correlated with the total body potassium. Epidemiologic, experimental, and clinical studies have shown that potassium is a significant regulator of BP and further improves cardiovascular outcomes. Hypertensive cardiovascular damage, stroke, and stroke-related death are accelerated by salt intake but might be curbed by increasing dietary potassium intake. The antihypertensive effect of potassium supplementation appears to occur through several mechanisms t...
Source: Journal of the American Society of Hypertension - June 3, 2013 Category: Cardiology Authors: Mehmet Kanbay, Yeter Bayram, Yalcin Solak, Paul W. Sanders Tags: Review Articles Source Type: research

An exaggerated blood pressure response to exercise is associated with the dietary sodium, potassium, and antioxidant vitamin intake in normotensive subjects.
CONCLUSIONS: These results suggest that an exaggerated SBP response to exercise was associated with the dietary sodium, potassium, and antioxidant vitamin intake in normotensive subjects. PMID: 29553836 [PubMed - as supplied by publisher]
Source: Clinical and Experimental Hypertension - March 19, 2018 Category: Cardiology Authors: Michishita R, Ohta M, Ikeda M, Jiang Y, Yamato H Tags: Clin Exp Hypertens Source Type: research

Network meta-analysis of efficacy and safety of chlorthalidone and hydrochlorothiazide in hypertensive patients
Hypertension is a chronic condition leading to increased stress on the heart and blood vessels, a critical risk factor for clinically significant events such as myocardial infarction heart failure, stroke and death. Chlorthalidone and hydrochlorothiazide are first-line antihypertensive agents for most patients with hypertension. The aim of our meta-analysis was to compare the efficacy and safety of both therapies in patients with hypertension. Searches of electronic databases PubMed, MEDLINE, Scopus, PsycInfo and eLIBRARY.ru, were performed. We used network meta-analysis to combine direct and indirect evidence. Forest plot...
Source: Blood Pressure Monitoring - March 11, 2021 Category: Cardiology Tags: Review Article Source Type: research

Mineralocorticoid receptor antagonism improves transient receptor potential vanilloid 4-dependent dilation of cerebral parenchymal arterioles and cognition in a genetic model of hypertension
Conclusions: These data advance our understanding of the effects of hypertension on cerebral arterioles using a clinically relevant model and treatment paradigm. Our studies suggest TRPV4 and the MR are potential therapeutic targets to improve cerebrovascular function and cognition during hypertension.
Source: Journal of Hypertension - August 13, 2022 Category: Cardiology Tags: ORIGINAL ARTICLES Source Type: research

Effects of salt substitutes on clinical outcomes: a systematic review and meta-analysis
Conclusions The beneficial effects of salt substitutes on blood pressure across geographies and populations were consistent. Blood pressure-mediated protective effects on clinical outcomes are likely to be generalisable across population subgroups and to countries worldwide. Trial registration number CRD42020161077.
Source: Heart - September 26, 2022 Category: Cardiology Authors: Yin, X., Rodgers, A., Perkovic, A., Huang, L., Li, K.-C., Yu, J., Wu, Y., Wu, J. H. Y., Marklund, M., Huffman, M. D., Miranda, J. J., Di Tanna, G. L., Labarthe, D., Elliott, P., Tian, M., Neal, B. Tags: Press releases Cardiac risk factors and prevention Source Type: research