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Which aortic clamp strategy is better to reduce postoperative stroke and death: Single center report and a meta-analysis
Background: Stroke is severe complication of coronary artery bypass grafting (CABG) which may be associated with clamp strategy, there are 2 strategies to clamp aorta including single aortic clamp (SAC) and partial aortic clamp (PAC). It is controversial that which clamping strategy is better to reduce the postoperative stroke and death, so this study aims to investigate which is better for reducing postoperative stroke and death within 30 days. Methods: We collected 469 patients who had on-pump CABG in Fuwai Hospital during January 2014 to July 2015. The SAC group consisted of 265 patients while the PAC group include...
Source: Medicine - March 1, 2018 Category: Internal Medicine Tags: Research Article: Systematic Review and Meta-Analysis Source Type: research

Rho-Associated Kinase Activity Is a Predictor of Cardiovascular Outcomes Cardiovascular Outcomes
Cardiovascular diseases are associated with chronic activation of Rho-associated kinase. Rho-associated kinase activity is significantly correlated with endothelial function and Framingham risk score. However, there is no information on the prognostic value of Rho-associated kinase activity. We evaluated Rho-associated kinase activity in peripheral leukocytes by Western blot analysis in 633 subjects who underwent health-screening examination at Hiroshima University Hospital. We assessed the associations between Rho-associated kinase activity and first major cardiovascular events (death from cardiovascular causes, myocardia...
Source: Hypertension - March 12, 2014 Category: Cardiology Authors: Kajikawa, M., Noma, K., Maruhashi, T., Mikami, S., Iwamoto, Y., Iwamoto, A., Matsumoto, T., Hidaka, T., Kihara, Y., Chayama, K., Nakashima, A., Goto, C., Liao, J. K., Higashi, Y. Tags: Risk Factors Cardiovascular Outcomes Source Type: research

Prevalence and impact of carotid disease in adult Saudi patients undergoing isolated coronary artery bypass surgery on early postoperative outcome
The aim of the study is to assess the prevalence of carotid disease in our Saudi population undergoing coronary artery bypass surgery and to determine its impact on stroke and early postoperative outcome. A total of 3197 consecutive adult patients underwent major cardiac surgery in our center between January 2002 and December 2012. Of these, 3150 had preoperative duplex scanning, and out of these, 210 patients (6.6%) had significant carotid artery disease defined as ≥75% stenosis (Group A), whereas 2940 (94.4%) were free from carotid artery disease (Group B). Both groups were compared for the presence of preoperative ri...
Source: European Journal of Heart Failure Supplements - November 10, 2014 Category: Cardiology Authors: Arifi, A. A., Ahmad, M., Van Onselen, R., Najm, H. K. Tags: Articles Source Type: research

Prior chronic clopidogrel therapy is associated with increased adverse events and early stent thrombosis.
Abstract Despite the growing use of clopidogrel, limited data exist regarding the prognostic significance of chronic clopidogrel therapy in patients sustaining acute coronary syndrome (ACS). Our aim was to determine whether patients sustaining ACS while on chronic clopidogrel therapy have a worse prognosis than clopidogrel-naïve patients. A total of 5,386 consecutive ACS patients were prospectively characterised and followed-up for 30 days. Of them, 680 (13 %) were treated with clopidogrel prior to the index ACS. Major adverse cardiovascular events (MACE) were defined as death, recurrent ACS, stroke and/or sten...
Source: Thrombosis and Haemostasis - October 8, 2015 Category: Hematology Authors: Asher E, Fefer P, Sabbag A, Herscovici R, Regev E, Mazin I, Shlomo N, Zahger D, Atar S, Hammerman H, Polak A, Beigel R, Matetzky S, PLATIS (Platelets and Thrombosis in Sheba) Study Group Tags: Thromb Haemost Source Type: research

Not Just Acid Reflux: The Need to Think Worst First
Discussion Heart disease is the leading cause of death in the United States.1 This year, 720,000 Americans will have a new coronary event—defined as first hospitalized myocardial infarction (MI) or coronary heart disease death—and around 335,000 will have a recurrent event. Approximately 35% of people who experience a coronary event in a given year and around 14% of patients who have an acute coronary syndrome will die from it.1 Roughly 60% of patients with an acute coronary syndrome are transported to the emergency department via ambulance.2–4. Up to one-third of patients experiencing an MI may not complain of chest...
Source: JEMS Special Topics - January 13, 2019 Category: Emergency Medicine Authors: Stephen Sanko, MD, FACEP Tags: Exclusive Articles Cardiac & Resuscitation Source Type: news

Trans ‐ventricular catheter device‐based closure of postmyocardial infarction ventricular septal defect following coronary artery bypass grafting: A staged hybrid approach
AbstractA 66 ‐year‐old woman with a history of hypertension, ischemic stroke, and rheumatoid arthritis presented to the hospital with severe angina pectoris and dyspnea and was diagnosed with myocardial infarction (MI). Coronary angiography revealed multisystem coronary artery occlusive disease. Due to refra ctory myocardial ischemia/evolving MI, emergency coronary artery bypass grafting (CABG) was undertaken. Intraoperative transesophageal echocardiography additionally revealed an apical muscular ventricular septal defect (VSD). Concomitant VSD repair was deferred due to the absence of surface evidence of transmural M...
Source: Journal of Cardiac Surgery - January 27, 2021 Category: Cardiovascular & Thoracic Surgery Authors: Pranav Loyalka, Faisal H. Cheema, Shakeel Thakurdas, Keshava Rajagopal, Abdul Hannan Chaugle Tags: CASE REPORT Source Type: research