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Condition: Tetanus
Vaccination: Vaccines
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Total 957 results found since Jan 2013.
A thermostable tetanus/diphtheria (Td) vaccine in the StablevaX ™ pre-filled delivery system
Vaccine. 2023 Apr 28:S0264-410X(23)00431-0. doi: 10.1016/j.vaccine.2023.04.039. Online ahead of print.ABSTRACTA syringe for the long-term, room-temperature storage and injection of vaccines is described. Stabilisation was achieved by drying from a trehalose-containing buffer which formed an inert soluble glass distributed in the internal interconnected voids in an absorbent, compliant, reticulated, medical-grade, porous sponge. The sponge is stored inside the barrel of a syringe and the vaccines are re-solubilised by the aspiration of water. The syringe contains the sponge throughout the filling and drying processes in man...
Source: Vaccine - April 30, 2023 Category: Allergy & Immunology Authors: Juana de la Torre Arrieta Daniela Brice ño Ivan Garcia de Castro Bruce Roser Source Type: research
Low Vaccine Coverage and Factors Associated with Incomplete Childhood Immunization in Racial/Ethnic Minorities and Rural Groups, Central Brazil
Vaccines (Basel). 2023 Apr 13;11(4):838. doi: 10.3390/vaccines11040838.ABSTRACTDiscrimination and limited access to healthcare services in remote areas can affect vaccination coverage. Therefore, this study aimed to estimate vaccination coverage for children living in quilombola communities and rural settlements in the central region of Brazil during their first year of life and to analyze the factors associated with incomplete vaccination. An analytical cross-sectional study was conducted on children born between 2015 and 2017. The percentage of children who received all vaccines recommended by the National Immunization P...
Source: Rural Remote Health - April 28, 2023 Category: Rural Health Authors: Juliana de Oliveira Roque E Lima Val éria Pagotto B árbara Souza Rocha Paulo S érgio Scalize Rafael Alves Guimar ães M árcio Dias de Lima Leandro Nascimento da Silva Michele Dias da Silva Oliveira Winny Éveny Alves Moura Sheila Ara újo Teles Claci Source Type: research
Tdap vaccination during pregnancy and risk of chorioamnionitis and related infant outcomes
CONCLUSIONS AND RELEVANCE: Tdap vaccine exposure during pregnancy was not associated with chorioamnionitis, preterm birth, or adverse infant outcomes. ICD-10 codes for chorioamnionitis lack specificity for clinical chorioamnionitis and should be a recognized limitation when interpreting results.PMID:37117057 | DOI:10.1016/j.vaccine.2023.04.043
Source: Vaccine - April 28, 2023 Category: Allergy & Immunology Authors: Victoria Greenberg Gabriela Vazquez-Benitez Elyse O Kharbanda Matthew F Daley Hung Fu Tseng Nicola P Klein Allison L Naleway Joshua T B Williams James Donahue Lisa Jackson Eric Weintraub Heather Lipkind Malini B DeSilva Source Type: research
Lack of seroprotection against diphtheria in the Austrian population, in light of reported diphtheria cases in Europe, 2022
Euro Surveill. 2023 Apr;28(17). doi: 10.2807/1560-7917.ES.2023.28.17.2300206.ABSTRACTFollowing an increase in diphtheria cases in Europe since 2022, we retrospectively estimated the prevalence of seroprotection against diphtheria and tetanus in 10,247 Austrian residents (population: 8,978,929) voluntarily tested between 2018 and 2022. Lack of seroprotection against diphtheria was found in 36% compared with 4% against tetanus. The geometric mean antibody concentration against tetanus was 7.9-fold higher compared with that for diphtheria. Raising awareness of regular booster vaccinations against diphtheria in combination wit...
Source: Euro Surveill - April 27, 2023 Category: Infectious Diseases Authors: Angelika Wagner Joanna Jasinska Daniela Schmid Michael Kundi Ursula Wiedermann Source Type: research
Development of a multiplex-based immunoassay for the characterization of diphtheria, tetanus and acellular pertussis antigens in human combined DTaP vaccines
J Immunol Methods. 2023 Apr 24:113483. doi: 10.1016/j.jim.2023.113483. Online ahead of print.ABSTRACTRoutine batch quality testing before vaccine release, notably for potency evaluation, still relies on animal use for several animal and human vaccines. In this context, the VAC2VAC project is a public-private consortium of 22 partners funded by EU whose the main objective is to reduce the number of animal used for batch testing by developing immunoassays that could be implemented for routine potency assessment of vaccines. This paper focused on the development of a Luminex-based multiplex assay to monitor the consistency of...
Source: Journal of Immunological Methods - April 26, 2023 Category: Allergy & Immunology Authors: Vermeulen Maxime Feck Isabelle Francotte Antoine Laura Hassall Tesolin Lorenzo Van Molle Wim Pizzato Romain Laurent Thierry Hoebreck Charline Stickings Paul Dobly Alexandre Source Type: research
Suspected tetanus in an unvaccinated pediatric patient
We present a case of suspected tetanus in a 10-year-old unvaccinated child in Central Texas who sustained multiple cardiovascular and pulmonary complications during a 1-month hospitalization course. This case highlights the importance of pediatric immunization for prevention of this potentially fatal disease process and its long-term complications. Physicians should maintain a high clinical suspicion for tetanus infection in unvaccinated children to prevent delay in necessary treatment.PMID:37091757 | PMC:PMC10120531 | DOI:10.1080/08998280.2023.2167048
Source: Baylor University Medical Center Proceedings - April 24, 2023 Category: Universities & Medical Training Authors: Kimberly Walter Renita Thomas Swasti Gyawali Sowmya Kallur Source Type: research
