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Overweight teen boys have increased risk of stroke in later life
Conclusion The findings of this large longitudinal cohort study seem to demonstrate a link between being overweight aged 20 and an increased risk of stroke. This risk was regardless of whether the boy had been overweight aged 8 or not. There seemed to be no increased risk for boys who were overweight aged 8 but were a normal weight by the age of 20. The study was conducted before the obesity epidemic, and might be even more relevant today. But there are a number of considerations to take into account before we draw any conclusions: Participants were followed up until they were 52-68, so all the strokes occurred at a r...
Source: NHS News Feed - June 29, 2017 Category: Consumer Health News Tags: Obesity Pregnancy/child Source Type: news

Postmenopausal hormone therapy and risk of stroke: A pooled analysis of data from population-based cohort studies
by Germ án D. Carrasquilla, Paolo Frumento, Anita Berglund, Christer Borgfeldt, Matteo Bottai, Chiara Chiavenna, Mats Eliasson, Gunnar Engström, Göran Hallmans, Jan-Håkan Jansson, Patrik K. Magnusson, Peter M. Nilsson, Nancy L. Pedersen, Alicja Wolk, Karin Leander BackgroundRecent research indicates a favourable influence of postmenopausal hormone therapy (HT) if initiated early, but not late, on subclinical atherosclerosis. However, the clinical relevance of timing of HT initiation for hard end points such as stroke remains to be determined. Further, no previous research has considered the timing of initiation of HT i...
Source: PLoS Medicine - November 17, 2017 Category: Internal Medicine Authors: Germ án D. Carrasquilla Source Type: research

Forty-four-year longitudinal study of stroke incidence and risk factors - the Prospective Population Study of Women in Gothenburg
CONCLUSIONS: Several classic risk factors showed independent associations with stroke. Vulnerability factors as low education and oral health, reflected by loss of teeth, also showed association with stroke. All these factors are possible to target in primary care preventive interventions.Key PointsStroke is a common disease and the risk of stroke is a key issue demanding preventive strategies in primary health care. The present prospective population study of women showsOut of 1460 women, almost a quarter got a stroke. The stroke incidence 60-82 years of age was rather stable between the first four age cohorts but somewha...
Source: Primary Care - April 8, 2022 Category: Primary Care Authors: Ann Blomstrand Christian Blomstrand Magnus Hakeberg Valter Sundh Lauren Lissner Cecilia Bj örkelund Source Type: research

Prestroke physical activity and outcomes after intracerebral haemorrhage in comparison to ischaemic stroke: protocol for a matched cohort study (part of PAPSIGOT)
Introduction Piling evidence suggests that a higher level of prestroke physical activity can decrease stroke severity, and reduce the risk of poststroke mortality. However, prior studies have only included ischaemic stroke cases, or a majority of such. We aim to investigate how premorbid physical activity influences admission stroke severity and poststroke mortality in patients with intracerebral haemorrhage, compared with ischaemic stroke. A prespecified analysis plan counteract some inherent biases in observational studies, and promotes transparency. Methods and analysis This is a statistical analysis protocol for a mat...
Source: BMJ Open - November 19, 2021 Category: General Medicine Authors: Viktorisson, A., Buvarp, D., Sunnerhagen, K. S. Tags: Open access, Neurology Source Type: research

Identifying factors explaining practice variation in secondary stroke prevention in primary care: a cohort study based on all patients with ischaemic stroke in the Stockholm region
Conclusions A high practice variation for dispensation of all secondary preventive drugs was observed. Patient and PCC level factors indicating good continuity of care and high level of general practitioner education were associated with higher use of statins. Findings are of importance to policymakers as well as individual providers of care, and more research and actions are needed to minimise inequality in healthcare.
Source: BMJ Open - November 21, 2022 Category: General Medicine Authors: Wolf, M., Hasselström, J. K., Carlsson, A., Euler, M. v., Hasselström, J. Tags: Open access, Neurology Source Type: research

Psychosis Polyrisk Score (PPS) for the Detection of Individuals At-Risk and the Prediction of Their Outcomes
Conclusions The combination of risk/protective factors encompassing genetic (PRS) and non-genetic information (PPS) holds promise for overcoming the epidemiological weakness of the CHR-P paradigm. The PPS conceptually and empirically developed here will facilitate future research in this field and hopefully advance our ability to detect individuals at-risk for psychosis and forecast their clinical outcomes. Ethics Statement This study was supported by the King's College London Confidence in Concept award from the Medical Research Council (MRC) (MC_PC_16048) to PF-P. This study also represents independent researc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Attention-deficit/hyperactivity disorder as a risk factor for cardiovascular diseases: a nationwide population-based cohort study
World Psychiatry. 2022 Oct;21(3):452-459. doi: 10.1002/wps.21020.ABSTRACTAccumulating evidence suggests a higher risk for cardiovascular diseases among individuals with mental disorders, but very little is known about the risk for overall and specific groups of cardiovascular diseases in people with attention-deficit/hyperactivity disorder (ADHD). To fill this knowledge gap, we investigated the prospective associations between ADHD and a wide range of cardiovascular diseases in adults. In a nationwide population-based cohort study, we identified 5,389,519 adults born between 1941 and 1983, without pre-existing cardiovascul...
Source: World Psychiatry - September 8, 2022 Category: Psychiatry Authors: Lin Li Zheng Chang Jiangwei Sun Miguel Garcia-Argibay Ebba Du Rietz Maja Dobrosavljevic Isabell Brikell Tomas Jernberg Marco Solmi Samuele Cortese Henrik Larsson Source Type: research

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