• Filter By:
• Specialty
• Source
• Condition
• Cancer
• Infectious Disease
• Drug
• Training
• Management
• Procedure
• Therapy
• Vaccine
• Nutrition
• Country

Fetal Alcohol Exposure Alters Blood Flow and Neurological Responses to Transient Cerebral Ischemia in Adult Mice.
CONCLUSIONS: Our data collectively show that PAE adult mice exhibit a persistent, long-term loss of cranially directed blood flow, and decreased capacity to compensate for brain trauma due to acute-onset adult diseases like ischemic stroke. PMID: 27987329 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - December 16, 2016 Category: Addiction Authors: Bake S, Gardner R, Tingling JD, Miranda RC, Sohrabji F Tags: Alcohol Clin Exp Res Source Type: research

Damage to the insula leads to decreased nicotine withdrawal during abstinence
ConclusionsCurrent smokers with damage to their insular cortex brain region appear to experience fewer and less severe tobacco withdrawal symptoms, and appear to be less likely to require nicotine replacement therapy during hospitalization, compared with smokers with non‐insular damage. These findings support the potential role of the insular cortex in regulating withdrawal during abstinence, a motivator responsible for the maintenance of addictive behaviors.
Source: Addiction - September 8, 2015 Category: Addiction Authors: Amir Abdolahi, Geoffrey C. Williams, Curtis G. Benesch, Henry Z. Wang, Eric M. Spitzer, Bryan E. Scott, Robert C. Block, Edwin Wijngaarden Tags: Research Report Source Type: research

Effects of Chronic Alcohol Exposure on the Modulation of Ischemia-Induced Glutamate Release via Cannabinoid Receptors in the Dorsal Hippocampus.
CONCLUSIONS: Together, these findings suggest that loss of expression/function of CB1 receptors, but not CB2 receptors in the DH, is correlated with the enhancement of ischemia-induced glutamate release after prolonged alcohol withdrawal. PMID: 26343919 [PubMed - as supplied by publisher]
Source: Alcoholism, Clinical and Experimental Research - September 7, 2015 Category: Addiction Authors: Zheng L, Wu X, Dong X, Ding X, Song C Tags: Alcohol Clin Exp Res Source Type: research

Effects of Chronic Alcohol Exposure on the Modulation of Ischemia‐Induced Glutamate Release via Cannabinoid Receptors in the Dorsal Hippocampus
ConclusionsTogether, these findings suggest that loss of expression/function of CB1 receptors, but not CB2 receptors in the DH, is correlated with the enhancement of ischemia‐induced glutamate release after prolonged alcohol withdrawal.
Source: Alcoholism: Clinical and Experimental Research - September 1, 2015 Category: Addiction Authors: Lei Zheng, Xiaoda Wu, Xiao Dong, Xinli Ding, Cunfeng Song Tags: Original Article Source Type: research

Cigarette Smoking and Alcohol use as Predictors of Disability Retirement: A Population-Based Cohort Study
Tobacco use and excess alcohol consumption are both risk factors for several chronic diseases. Tobacco use is a leading preventable risk factor for premature mortality (World Health Organization (WHO), 2009), accounting for 18% of deaths in high-income countries (WHO, 2009a,b), and being second only to high blood pressure globally (9% vs. 13% of deaths, respectively). Smoking raises the risk of chronic diseases such as heart disease, diabetes and cancers (WHO, 2009a,b). Compared to never smokers, smokers have a 25-fold risk of death due to Chronic Obstructive Pulmonary Disease (COPD), a 2.5-fold risk due to ischemic heart ...
Source: Drug and Alcohol Dependence - August 10, 2015 Category: Addiction Authors: Tellervo Korhonen, Eero Smeds, Karri Silventoinen, Kauko Heikkilä, Jaakko Kaprio Tags: Full length article Source Type: research

Associations of Lifetime Abstention and Past and Current Alcohol Use with Late-Life Mental Health: A Propensity Score Analysis
A recent review of studies that examined health effects of alcohol consumption concludes that habitual light-to-moderate alcohol intake (up to 1 drink per day for women and 1 or 2 drinks per day for men) is associated with lower rates of death, coronary artery disease, congestive heart failure, diabetes mellitus, and stroke (O’Keefe et al., 2014). The review also reports that excessive alcohol intake, in a dose-dependent fashion, commonly causes irreversible hypertension and atrial fibrillation, accounts for one third of all cases of nonischemic dilated cardiomyopathy, and markedly increases risks of both ischemic...
Source: Drug and Alcohol Dependence - February 16, 2015 Category: Addiction Authors: C. Nathan Marti, Namkee G. Choi, Diana M. DiNitto, Bryan Y. Choi Tags: Full length article Source Type: research

Chronic diseases and conditions related to alcohol use.
Authors: Shield KD, Parry C, Rehm J Abstract Alcohol consumption is a risk factor for many chronic diseases and conditions. The average volume of alcohol consumed, consumption patterns, and quality of the alcoholic beverages consumed likely have a causal impact on the mortality and morbidity related to chronic diseases and conditions. Twenty-five chronic disease and condition codes in the International Classification of Disease (ICD)-10 are entirely attributable to alcohol, and alcohol plays a component-risk role in certain cancers, other tumors, neuropsychiatric conditions, and numerous cardiovascular and digestiv...
Source: Alcohol Research - November 25, 2014 Category: Addiction Tags: Alcohol Res Source Type: research

Recreational drug misuse and stroke.
Authors: Yeung M, Bhalla A, Birns J Abstract Stroke is the third commonest cause of death and single largest cause of adult disability worldwide. Whilst the majority of strokes in older individuals are due to large or small vessel arterial disease or cardiac disease in association with classical vascular risk factors, strokes occurring in younger individuals may have atypical etiologies. Recreational substance misuse is on the increase worldwide, particularly in young adults in developed countries with commonly used substances including cocaine, amphetamines, heroin and other opiates, marijuana and gammahydroxybuty...
Source: Current Drug Abuse Reviews - November 14, 2014 Category: Addiction Tags: Curr Drug Abuse Rev Source Type: research

Pages: 1  2  3  4  5  6  7  8  9  10