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Condition: Ischemic Stroke
Infectious Disease: COVID-19
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Total 1593 results found since Jan 2013.
Intravenous thrombolysis and endovascular therapy for acute ischemic stroke in COVID-19: a systematic review and meta-analysis
ConclusionCOVID-19 appears to have an adverse impact on acute ischemic stroke patients who undergo reperfusion therapy, leading to an elevated risk of any ICH, higher mortality and lower likelihood of favorable functional outcome.Systematic review registrationhttps://clinicaltrials.gov/, identifier CRD42022309785.
Source: Frontiers in Neurology - August 15, 2023 Category: Neurology Source Type: research
First experience of international proctoring hands-on stroke course using Tegus telemedical system for overcoming education challenges during the war in Ukraine
Interv Neuroradiol. 2023 Aug 9:15910199231193912. doi: 10.1177/15910199231193912. Online ahead of print.ABSTRACTInterventional neuroradiology (INR) has not yet received official certification as a surgical subspecialty in Ukraine. Consequently, there is uncertainty surrounding the availability of a neurosurgical internship and a structured INR training program to provide neuroendovascular procedures. In recent years, mechanical thrombectomy has become the standard of care for acute ischemic stroke caused by large vessel occlusion, as supported by evidence-based guidelines. This emphasizes the need for INR specialists, whic...
Source: Interventional Neuroradiology - August 10, 2023 Category: Radiology Authors: Dmytro Shchehlov Jens Fiehler Mykola Vyval Anna A Kyselyova Source Type: research
Ischemic strokes in COVID-19: risk factors, obesity paradox, and distinction between trigger and causal association
ConclusionOur stroke occurrence rate is consistent with other population-based reports (range 0.34–2.7%). Prespecified peculiar clinical and radiological features allow the distinction between “IS caused by COVID-19” and “IS triggered by COVID-19.” Clinical history of vascular diseases and risk factors is crucial in determining the risk of IS in patients with COVID-19. However, the protective effect of a BMI > 30 kg/m2 seems to suggest an obesity paradox.
Source: Frontiers in Neurology - August 1, 2023 Category: Neurology Source Type: research
E-132 Successful mechanical thrombectomy in an 11-year-old patient with emergent large vessel occlusion acute ischemic stroke related to congenital complete heart block and recent covid-19 infection
ConclusionsThis is a first known report of a successful mechanical thrombectomy in a pediatric patient due to a large vessel occlusion related to congenital complete heart block and recent COVID-19 infection.Disclosures J. Ansari: None. D. Mata Canadas: None. M. Ayub: None. J. Caskey: None. P. Simoncini: None. R. Riel-Romero: None. P. Sharma: None. D. Jordan: None. H. Cuellar: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ansari, J., Mata Canadas, D., Ayub, M., Caskey, J., Simoncini, P., Riel-Romero, R., Sharma, P., Jordan, D., Cuellar, H. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-145 Mortality following mechanical thrombectomy for ischemic stroke in patients with COVID-19
ConclusionOverall, this study indicates that COVID-19 is a predictor of mortality among mechanical thrombectomy. This finding is likely multifactorial but may be related to multisystem inflammation, hypercoagulability, and re-occlusion seen in COVID-19 patients. Treatment-related factors, such as delays in care, may also play a role. Additional research would be needed to further delineate these findings.Disclosures J. Dallas: None. T. Wenger: None. K. Liu: None. L. Ding: None. B. Hopkins: None. F. Attenello: None. W. Mack: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Dallas, J., Wenger, T., Liu, K., Ding, L., Hopkins, B., Attenello, F., Mack, W. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-164 Symptomatic developmental venous anomaly thrombosis associated with covid-19 infection
We describe a milder case of DVA thrombosis in the setting of COVID-19 infection presenting with unilateral hemiparesis requiring medical management alone. A 41-year-old female with hypertension who presented with left hemiparesis. Non-contrast computed tomography (CT) of head revealed linear calcifications in the right centrum semiovale consistent with DVA. Magnetic resonance imaging (MRI) revealed an acute ischemic stroke in the right corona radiata adjacent to the vascular abnormality. Extensive workup for other causes of ischemic stroke was unrevealing. Cerebral angiography ruled out arteriovenous shunting and did not ...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Eby, B., Khasawneh, M. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-166 The effect of covid-19 on treatment and outcomes following ischemic stroke: a national assessment
ConclusionThis study identified a relationship between COVID-19 diagnosis and worse outcomes for each metric assessed. Most notably, even when controlling for disease-related factors, patients with COVID-19 were significantly less likely to undergo mechanical thrombectomy. Further, COVID-19 was associated with increased in-hospital mortality and worsened discharge disposition, although the exact causal relationship of this is unclear. Several factors might underly this, ranging from systemic/multisystem inflammation and worsened disease severity to logistical barriers to treatment caused by COVID-19. Further research is ne...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Dallas, J., Liu, K., Wenger, T., Lin, M., Ding, L., Attenello, F., Mack, W. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-177 Treatment of ischemic stroke in patients diagnosed with covid-19: a matched analysis of the national inpatient sample
ConclusionsIn this matched NIS analysis of patients treated for ischemic stroke with a concomitant COVID diagnosis, we demonstrate that EVT trends towards, although nonsignificant, higher rates of favorable functional outcomes when compared to medically managed patients.Abstract E-177 Table 1Patients with COVID and Acute Ischemic Stroke Comparing medical management vs EVT 1:1 Nearest Neighbor Matching for EVT based on Age, NIHSS, Gender, and Comorbidities Medically Managed N = 495 1 Endovascular ThrombectomyN = 495 1 p-value 2 Age in years at admission 66.82 ± 16.98 (19.00-90.00), (1.77) 65.67 ± 14.81 (28...
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Heskett, C., Fry, L., Brake, A., De Stefano, F., Morey, K., Lei, C., Alkiswani, A., Le, K., Peterson, J., Ebersole, K. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
E-241 Clinicopathologic analysis of COVID-19 associated thrombi in the setting of large vessel occlusion: a prospective case control study
ConclusionThrombi retrieved from COVID-19 positive stroke patients demonstrated RBC predominance. This finding requires further investigation using appropriate immunohistochemical techniques in a larger cohort of patients.Abstract E-241 Figure 1Abstract E-241 Figure 2COVID-19 positive patient thrombus; stained with H&E demonstrating predominantly RBCs (solid yellow arrow) with interspersed fibrin (solid black arrow) and platelets. Original magnification X100Disclosures R. Floresca: None. F. Sheriff: None. J. Lavezo: None. M. Chaudhury: None. G. Colina: None. R. Regenhardt: None. V. Gupta: None. G. Rodriguez: None. A. Maud: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Floresca, R., Sheriff, F., Lavezo, J., Chaudhury, M., Colina, G., Regenhardt, R., Gupta, V., Rodriguez, G., Maud, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
P-028 Impact of the covid-19 pandemic on the intracranial aneurysm treatment and associated outcomes: a propensity score matching study
Conclusions and RelevanceThe COVID-19 pandemic has significantly impacted the healthcare system and has led to changes in the treatment of various neurological conditions, including ICAs. The pandemic resulted in a shift in the treatment of SAH and an increase in endovascular procedures over open surgical clipping. COVID-19 infection has been associated with an increased risk of ischemic stroke and worsened outcomes for stroke patients. Further research is necessary to understand the long-term effects of the pandemic on the healthcare system and patient outcomes.Disclosures A. Ghaith: None. M. Ghanem: None. E. Greco: None....
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Ghaith, A., Ghanem, M., Greco, E., Rios-Zermeno, J., Bon Nieves, A., Kashyap, S., Tawk, R., Bydon, M. Tags: SNIS 20th annual meeting oral poster abstracts Source Type: research
E-069 Covid-19 and mechanical thrombectomy: confounder or contributor
ConclusionLate in the pandemic, mortality rates remain very high for patients with COVID-19 undergoing mechanical thrombectomy. This is significant in that later circulating variants appear to cause less severe disease.Disclosures C. Houk: None. N. Ellens: None. G. Kohli: None. D. Schartz: None. D. Proper: None. T. Bhalla: None. M. Bender: None. T. Mattingly: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Houk, C., Ellens, N., Kohli, G., Schartz, D., Proper, D., Bhalla, T., Bender, M., Mattingly, T. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research
Ischemic Stroke With Supratherapeutic INR Following COVID-19 Ischemic Stroke With Supratherapeutic INR Following COVID-19
This case report highlights the potential for thromboembolic events in patients with COVID-19 infection, even when receiving therapeutic anticoagulation therapy.Journal of Medical Case Reports
Source: Medscape Today Headlines - July 21, 2023 Category: Consumer Health News Tags: Family Medicine/Primary Care Journal Article Source Type: news
Viruses, Vol. 15, Pages 1598: Cerebrovascular Disease in COVID-19
h N. Nguyen
Not in the history of transmissible illnesses has there been an infection as strongly associated with acute cerebrovascular disease as the novel human coronavirus SARS-CoV-2. While the risk of stroke has known associations with other viral infections, such as influenza and human immunodeficiency virus, the risk of ischemic and hemorrhagic stroke related to SARS-CoV-2 is unprecedented. Furthermore, the coronavirus disease 2019 (COVID-19) pandemic has so profoundly impacted psychosocial behaviors and modern medical care that we have witnessed shifts in epidemiology and have adapted our treatment practices to ...
Source: Viruses - July 21, 2023 Category: Virology Authors: James E. Siegler Savanna Dasgupta Mohamad Abdalkader Mary Penckofer Shadi Yaghi Thanh N. Nguyen Tags: Review Source Type: research
Cerebrovascular disease in patients with COVID-19 infection: a case series from Lebanon
Ann Med Surg (Lond). 2023 Jun 10;85(7):3701-3708. doi: 10.1097/MS9.0000000000000953. eCollection 2023 Jul.ABSTRACTCOVID-19 has been associated with a variety of multi-organs complications, with an increasing proportion of patients presenting with neurologic manifestations. There is still an uncertainty in the relationship between stroke and COVID-19. Therefore, in this study, the authors report 18 cases of acute stroke occurring in the setting of COVID-19 infection, including 11 ischaemic strokes and 7 haemorrhagic strokes and identified in a Lebanese tertiary hospital. In this case series, patients with ischaemic and haem...
Source: Annals of Medicine - July 10, 2023 Category: Internal Medicine Authors: Zeinab El Mawla Ghaidaa El Saddik Maya Zeineddine Mahmoud Hassoun Taghrid El Hajj Source Type: research
