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Condition: Ischemic Stroke
Infectious Disease: COVID-19

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Total 1593 results found since Jan 2013.

Anticoagulation strategies in COVID-19 infected patients receiving ECMO support
CONCLUSION: In hospitalized patients with COVID-19-associated acute respiratory distress syndrome (ARDS) on VV ECMO support, the use of bivalirudin showed to be a viable anticoagulation alternative in terms of efficacy compared to UFH and resulted in a favorable safety profile with lower rates of bleeding and thrombotic events.PMID:37682210 | PMC:PMC10487306 | DOI:10.1051/ject/2023027
Source: Journal of Extra-Corporeal Technology - September 8, 2023 Category: Cardiovascular & Thoracic Surgery Authors: Dayne Diaz Jenny Martinez Grant Bushman William R Wolowich Source Type: research

Bioinformatics analysis of carotid vulnerable plaques associated with the SARS-CoV-2 Pattern
Gene. 2023 Aug 31:147754. doi: 10.1016/j.gene.2023.147754. Online ahead of print.ABSTRACTThe rupture of carotid artery vulnerable plaque plays a critical role in ischemic stroke, and the widely spread new coronavirus in recent years plays a certain role in the development of human carotid artery vulnerable plaque, we screened out 27 differential expression genes (DEGs) of stable plaque and vulnerable plaque associated with the new coronavirus. Through the construction of the protein-protein interaction (PPI) network, the Cathepsin B (CTSB) and Niemann-Pick Disease Type 2 (NPC2) were identified as crucial expression genes, ...
Source: Gene - September 2, 2023 Category: Genetics & Stem Cells Authors: Tao Jiang Jiaming Huang Shupeng Li Qiushi Xu Tianding Zhang Xianwei Wang Dong Chen Source Type: research

Neurological manifestations of SARS-CoV-2: complexity, mechanism and associated disorders
CONCLUSIONS: SARS-CoV-2 can lead to neurological complications, such as cerebrovascular manifestations, motor movement complications, and cognitive decline. COVID-19 infection can result in cerebrovascular symptoms and diseases, such as strokes and thrombosis. The virus can affect the neural system, disrupt cognitive function and cause neurological disorders. To combat the epidemic, it is crucial to repurpose drugs currently in use quickly and develop novel therapeutics.PMID:37649125 | PMC:PMC10469568 | DOI:10.1186/s40001-023-01293-2
Source: Cell Research - August 30, 2023 Category: Cytology Authors: Kritika Tyagi Prachi Rai Anuj Gautam Harjeet Kaur Sumeet Kapoor Ashish Suttee Pradeep Kumar Jaiswal Akanksha Sharma Gurpal Singh Ravi Pratap Barnwal Source Type: research

Increased neuropil antibody prevalence in COVID-19 patients with acute ischemic stroke
CONCLUSION: Our results confirm the presence of neuropil antibodies in patients with COVID-19 infection and identify a putative antibody-driven association between AIS and COVID-19. The antigenic targets and potential pathogenic action of these antibodies need to be further explored.PMID:37634189 | DOI:10.1080/01616412.2023.2252282
Source: Cell Research - August 27, 2023 Category: Cytology Authors: Birg ül Baştan Ece Erda ğ Turgeon Elif Şanlı Muhammet Duran Bayar Aysel B üşra Şişman Miray Atacan Ya şgüçlükal Cem I Smail K üçükali Erdem T üzün Sefer G ünaydın Source Type: research

Single-cell RNA sequencing and multiple bioinformatics methods to identify the immunity and ferroptosis related biomarkers of SARS-CoV-2 infections to ischemic stroke
CONCLUSION: We believe these genes (B4GALT5, CRISPLD2, F5, ACSL1, CREB5) may regulate the immune response and ferroptosis of multiple immune cells, mainly including monocytes, which may contribute to the development of COVID-19-related IS. In addition, these genes may be potential targets for the treatment of COVID-19-related IS.PMID:37606960 | DOI:10.18632/aging.204966
Source: Aging - August 22, 2023 Category: Biomedical Science Authors: Xiang Zhao Qingyu Liang Hao Li Zhitao Jing Dongmei Pei Source Type: research

P009/86 Infected giant pseudoaneurysm of extracranial internal carotid artery with extreme vascular tortuosity: Difficulty in accessing the devices in endovascular treatment
ConclusionWhen we deciding treatment strategy, surgery could not be considered due to uncontrolled infection and suggesting inflammatory/erosive changes. Because of no collateral flow, carotid sacrifice could not be considered. Endovascular treatment is preferred option, but treatment strategy should be personalized.Disclosure of InterestNothing to disclose
Source: Journal of NeuroInterventional Surgery - August 21, 2023 Category: Neurosurgery Authors: Yang, J.-C., Hong, C. E., Han, M. H., Lee, J. Tags: 4.3 CASE PROPOSAL - Acute ischemic stroke Source Type: research

The influence of COVID-19 on the treatment of patients with acute ischemic stroke: a  retrospective observational study
CONCLUSIONS: The pandemic situation of COVID-19 significantly reduced the number of patients with AIS and prolonged the travel time to the hospital whereas most of the stroke treatment services were maintained.PMID:37587891 | DOI:10.5114/fn.2023.124565
Source: Folia Neuropathologica - August 17, 2023 Category: Neurology Authors: Wei Chen Fangju Lin Wei Zhao Baoling Yang Weihua Jia Source Type: research