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Wernicke Encephalopathy Mimicking MELAS
CONCLUSIONS: the case suggests that thiamine deficiency presumably causes mitochondrial dysfunction with cerebrospinal fluid lactic acidosis and a stroke-like lesion mimicking MELAS syndrome. It should be further studied whether nutritional deficits, such as thiamine deficiency, could give rise to secondary stroke-like lesions.PMID:35630076 | PMC:PMC9144475 | DOI:10.3390/medicina58050660
Source: Medicina (Kaunas) - May 28, 2022 Category: Universities & Medical Training Authors: Josef Finsterer Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

A case of non-febrile seizures due to chronic salicylate intoxication following prolonged household exposure to incense stick fumes (p3.250)
Conclusion: All salicylate-containing products should have an appropriate warning label. It is important that health care providers are aware of the potential risk.Disclosure: Dr. Shekhawat has nothing to disclose. Dr. Rajagopalan has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Shekhawat, P., Rajagopalan, L. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Severe Hypoxia with Status Epilepticus as a Possible Etiology of Sudden Death in Lesch Nyhan Syndrome: A Case Report and Review of the Literature (P3.252)
CONCLUSIONS: Severe hypoxia secondary to unrecognized nocturnal seizures may be an etiology of sudden death in Lesch Nyhan syndrome. Neurotransmitter abnormalities have been described in LNS, including alterations in adenosine, a neurotransmitter associated with death from seizure in animal models. This could be responsible for increased incidence of sudden death from seizures in LNS.Disclosure: Dr. Christy has nothing to disclose. Dr. Wilson has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Christy, A., Wilson, J. Tags: Child Neurology and Developmental Neurology: Epilepsy, Hypoxia, and Stroke Source Type: research

Nursing Home Residents with Seizure Disorders/Epilepsy: Prevalence, Characteristics, and Treatment Patterns (P1.080)
Conclusions: NHRs with seizure disorder/epilepsy have substantial physical and cognitive impairment. Nearly half were prescribed combination AED therapy, and >20[percnt] took 蠅3 different AEDs, suggesting refractory epilepsy. Additional research is needed to assess treatment outcomes and further define optimal care in this population.Disclosure: Dr. Zarowitz has nothing to disclose. Dr. Allen has nothing to disclose. Dr. OShea has nothing to disclose. Dr. Wang has nothing to disclose. Dr. Semenchuk has nothing to disclose. Dr. Barghout has nothing to disclose.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Zarowitz, B., Allen, C., OShea, T., Wang, Z., Semenchuk, M., Barghout, V. Tags: Epilepsy/Clinical Neurophysiology: Geriatric Epilepsy, Epidemiology, and Health Services Source Type: research

De novo status epilepticus with isolated aphasia
Conclusions Magnetic resonance imaging findings were only subtle, and EEG was without clear ictal pattern, so the diagnosis of aphasic status remains with some uncertainty. However, status epilepticus can mimic stroke symptoms and has to be considered in patients with aphasia even when no previous stroke or structural lesions are detectable and EEG shows no epileptic discharges. Epileptic origin is favored when CT or MR imaging reveal no hypoperfusion. In this case, MRI was superior to CT in detecting hyperperfusion. This article is part of a Special Issue entitled “Status Epilepticus”.
Source: Epilepsy and Behavior - June 12, 2015 Category: Neurology Source Type: research

De novo status epilepticus with isolated aphasia.
CONCLUSIONS: Magnetic resonance imaging findings were only subtle, and EEG was without clear ictal pattern, so the diagnosis of aphasic status remains with some uncertainty. However, status epilepticus can mimic stroke symptoms and has to be considered in patients with aphasia even when no previous stroke or structural lesions are detectable and EEG shows no epileptic discharges. Epileptic origin is favored when CT or MR imaging reveal no hypoperfusion. In this case, MRI was superior to CT in detecting hyperperfusion. This article is part of a Special Issue entitled "Status Epilepticus". PMID: 26044094 [PubMed - as supplied by publisher]
Source: Epilepsy and Behaviour - June 1, 2015 Category: Neurology Authors: Flügel D, Kim OC, Felbecker A, Tettenborn B Tags: Epilepsy Behav Source Type: research

Epilepsia Partialis Continua Secondary To Ischemic Stroke, Responsive To The Combination Of Levetiracetam And Lacosamide (P4.255)
CONCLUSIONS: EPC represents a condition commonly refractory to AED. We report two cases of EPC secondary to subacute and chronic IS that showed responsiveness to the combination of levetiracetam and lacosamide. Further evaluation of this AED combination in treating this difficult condition is needed.Disclosure: Dr. Thompson has nothing to disclose. Dr. Murr has nothing to disclose. Dr. Fayad has received research support from the National Institute of Neurological Disorders and Stroke, and St Jude Medical.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Thompson, R., Murr, N., Fayad, P. Tags: Epilepsy and Clinical Neurophysiology (EEG): Status Epilepticus Source Type: research

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