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Anaphylaxis to Ultrasound-Enhancing Agent with Transient Elevation in Serum Tryptase
Ann Allergy Asthma Immunol. 2022 Apr 22:S1081-1206(22)00312-X. doi: 10.1016/j.anai.2022.04.015. Online ahead of print.NO ABSTRACTPMID:35470041 | DOI:10.1016/j.anai.2022.04.015
Source: Annals of Allergy, Asthma and Immunology - April 26, 2022 Category: Allergy & Immunology Authors: Alyssa Kerber James T C Li Source Type: research

Contrast enhanced ultrasound characterization of surgically resected renal masses in patients on dialysis.
Conclusions: In this sample of surgically resected tumors, CEUS was effective in characterizing renal lesions as solid neoplasms or complex cystic lesions suspicious for neoplasm-findings which merit further investigation. PMID: 31549563 [PubMed - as supplied by publisher]
Source: Scandinavian Journal of Urology - September 26, 2019 Category: Urology & Nephrology Tags: Scand J Urol Source Type: research

Epinephrine, auto-injectors and anaphylaxis: challenges of dose, depth and device.
CONCLUSION: EAIs should be available in the community with doses and needle depths that meet the needs of all patients. More research on epinephrine pharmacodynamics are needed in children and adults in anaphylaxis, in order to better delineate what optimal doses should be. Optimizing epinephrine dose and delivery has the potential to improve anaphylaxis outcomes and prevent adverse events. PMID: 29746901 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 7, 2018 Category: Allergy & Immunology Authors: Brown J Tags: Ann Allergy Asthma Immunol Source Type: research

Inadequacy of current pediatric epinephrine autoinjector needle length for use in infants and toddlers.
CONCLUSION: Our data suggest that the optimal EAI needle length for infants and toddlers weighing 7.5 to 15 kg should be shorter than the needle length in currently available pediatric EAIs to avoid accidental intraosseous injections. PMID: 28483294 [PubMed - as supplied by publisher]
Source: Annals of Allergy, Asthma and Immunology - May 5, 2017 Category: Allergy & Immunology Authors: Kim H, Dinakar C, McInnis P, Rudin D, Benain X, Daley W, Platz E Tags: Ann Allergy Asthma Immunol Source Type: research

Anaphylaxis following a transvaginal ultrasound
Polyethylene glycol is a ubiquitous, water-soluble, organic compound found in a wide variety of commercially available products. While generally a benign substance, in rare instances, it can induce hypersensitivity reactions. Herein, we describe a case of anaphylaxis to polyethylene glycol-containing lubricating gel used for a transvaginal ultrasound. This case highlights the importance of early recognition of a rare cause of anaphylaxis that may occur in the health-care setting. It is of particular importance given the widespread use of similar lubricating materials in multiple practice settings for the use of internal ex...
Source: Allergy, Asthma and Clinical Immunology - January 22, 2016 Category: Allergy & Immunology Authors: Baruch JakubovicCorey SaperiaGordon Sussman Source Type: research

Foods, Drugs and Environmental Factors: Novel Kounis Syndrome Offenders.
Authors: Kounis NG, Giannopoulos S, Soufras GD, Kounis GN, Goudevenos J Abstract Kounis syndrome is hypersensitivity coronary disorder induced by various types of environmental exposures, drugs, conditions and stents. Allergic, hypersensitivity, anaphylactic and anaphylactoid reactions are associated with this syndrome. The disorder manifests as coronary spasms, acute myocardial infarction and stent thrombosis and affects the cerebral and mesenteric as well as coronary arteries. Importantly, its manifestations are broad and its etiology is continuously increasing. Recently, a variety of unusual etiologies have been...
Source: Internal Medicine - July 4, 2015 Category: Internal Medicine Tags: Intern Med Source Type: research

Excess subcutaneous tissue may preclude intramuscular delivery when using adrenaline autoinjectors in patients with anaphylaxis
Abstract Intramuscular adrenaline is the gold standard treatment for anaphylaxis. Intramuscular injection provides more rapid and higher plasma concentrations than subcutaneous routes. Given the increasing epidemic of obesity patients are at increased risk of subcutaneous delivery, we therefore assessed the depth of subcutaneous tissue in a population of patients with anaphylaxis. Patients already prescribed adrenaline autoinjectors (AAIs) for anaphylaxis were examined with ultrasound, and measurements of skin‐to‐muscle depth (STMD) at anterolateral thigh and anterior thigh were performed. Twenty‐eight patients (23 f...
Source: Allergy - March 29, 2015 Category: Allergy & Immunology Authors: J. Johnstone, S. Hobbins, D. Parekh, S. O'Hickey Tags: Brief Communication Source Type: research

Excess subcutaneous tissue may preclude intramuscular delivery when using epinephrine autoinjectors in patients with anaphylaxis
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Source: Allergy - January 1, 2015 Category: Allergy & Immunology Authors: Jamie Johnstone, Stephanie Hobbins, Dhruv Parekh, Stephen O'Hickey Tags: Brief Communication Source Type: research