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Specialty: Cardiology
Condition: Diabetes
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Total 2993 results found since Jan 2013.
Participation by patients from low- and middle-income countries (LMICs) in trial evidence supporting secondary stroke prevention guideline recommendations
CONCLUSIONS: Compared to their global burden of stroke, LMICs are underrepresented in key clinical trials used in formulating a prominent global stroke prevention guideline. While current therapeutic recommendations are likely applicable to practice settings throughout the world, greater involvement of patients from LMIC settings will enhance the contextual relevance and generalizability of recommendations to these disparate populations.PMID:37028264 | DOI:10.1016/j.jns.2023.120641
Source: Atherosclerosis - April 7, 2023 Category: Cardiology Authors: Priscilla Abrafi Opare-Addo Fred Stephen Sarfo Patrick Opoku Berchie Minas Aikins Bruce Ovbiagele Source Type: research
Sex Differences in Outcomes of Ticagrelor Therapy With or Without Aspirin After Percutaneous Coronary Intervention in Patients With Acute Coronary Syndrome: A Post Hoc Secondary Analysis of the TICO Randomized Clinical Trial
CONCLUSIONS: After percutaneous coronary intervention for acute coronary syndrome, women demonstrated worse clinical outcomes than men. Ticagrelor monotherapy after 3-month dual-antiplatelet therapy was associated with significantly lower risk of net adverse clinical events in women without sex interaction.PMID:37021576 | DOI:10.1161/ATVBAHA.122.318725
Source: Arteriosclerosis, Thrombosis and Vascular Biology - April 6, 2023 Category: Cardiology Authors: Bom Lee Seung-Jun Lee Byeong-Keuk Kim Yong-Joon Lee Sung-Jin Hong Chul-Min Ahn Jung-Sun Kim Young-Guk Ko Donghoon Choi Meyong-Ki Hong Yangsoo Jang Source Type: research
The incomplete circle of Willis is associated with vulnerable intracranial plaque features and acute ischemic stroke
CONCLUSIONS: This study demonstrated that incomplete A-CoW was associated with enhancement grade of the culprit plaque, and incomplete symptomatic side P-CoW was associated with the presence of HT1S of culprit plaque. Furthermore, an irregularity of plaque surface and incomplete symptomatic side P-CoW were associated with AIS.PMID:37020230 | DOI:10.1186/s12968-023-00931-2
Source: Atherosclerosis - April 5, 2023 Category: Cardiology Authors: Huiying Wang Lianfang Shen Chenxi Zhao Song Liu Gemuer Wu Huapeng Wang Beini Wang Jinxia Zhu Jixiang Du Zhongying Gong Chao Chai Shuang Xia Source Type: research
Cardiac transplant and exercise cardiac rehabilitation
AbstractCardiac transplantation is the final therapeutic option for patients with end-stage heart failure. Most patients experience a favorable functional ability post-transplant. However, episodes of acute rejection, and multiple comorbidities such as hypertension, diabetes mellitus, chronic kidney disease and cardiac allograft vasculopathy are common. The number of transplants has increased steadily over the past two decades with 3,817 operations performed in the United States in 2021. Patients have abnormal exercise physiologic responses related to surgical cardiac denervation, diastolic dysfunction, and the legacy of r...
Source: Heart Failure Reviews - April 4, 2023 Category: Cardiology Source Type: research
Comparison of Prasugrel and Clopidogrel in Thrombotic Stroke Patients with Risk Factors for Ischemic Stroke Recurrence: An Integrated Analysis of PRASTRO-I, PRASTRO-II, and PRASTRO-III
CONCLUSIONS: This integrated analysis supports the findings of PRASTRO-III. Prasugrel is a promising treatment that results in a numerical reduction in the composite incidence of ischemic stroke, MI, and death from other vascular causes in patients with ischemic stroke who are at a high risk of stroke recurrence. No major safety issues were observed for prasugrel.PMID:37011599 | DOI:10.1159/000529149
Source: Atherosclerosis - April 3, 2023 Category: Cardiology Authors: Takanari Kitazono Masahiro Kamouchi Yuji Matsumaru Toshiaki Shirai Atsushi Takita Takeshi Kuroda Kazumi Kimura Source Type: research
Prediction of Coronary Artery Disease Severity by Using CHA2DS2-VASC-HSF Score in Patients with ST-Elevation Myocardial Infarction
In this study mean age of study population was 51.8±9.8, male patients were predominant (79.0%). Among the studied patients, highest percentage had history of smoking followed by hypertension, diabetes mellitus and family history of CAD in Group I patients. It was found that DM and family history of CAD and history of stroke/TIA were significantly higher in Group I than Group II. An increasing trend of SYNTAX score was observed according to the CHA₂DS₂-VASc-HSF score. SYNTAX score was significantly higher in CHA2DS2-VASc-HSF score ≥4 than CHA₂DS₂-VASc-HSF score <4 (26.3±6.3 vs. 12.1±7.7, p<0.001). Patien...
Source: Atherosclerosis - April 1, 2023 Category: Cardiology Authors: M A Rahim M J Uddin J Jahan T A Chowdhury A Momen M M Islam M A Rahman P Bala A Mamun F Chowdhury A R Majumder Source Type: research
Clinical characteristics, etiological profile, treatment and long term outcomes in patients with non ischemic systolic heart failure; Himachal Pradesh heart failure registry (HP-HF registry)
CONCLUSIONS: Patients of NISHF were middle-aged population with severely depressed LV systolic function with significant incident morbidity and mortality. Early detection of risk factors and their risk management and enhancing the use of guideline directed treatment may improve the outcomes.PMID:37003535 | DOI:10.1016/j.ihj.2023.03.007
Source: Indian Heart J - April 1, 2023 Category: Cardiology Authors: Prakash Chand Negi Ashu Gupta Meena Rana Sanjeev Asotra Neeraj Ganju Rajeev Marwah Rajesh Sharma Arvind Kandoria Source Type: research
Prediction of Coronary Artery Disease Severity by Using CHA2DS2-VASC-HSF Score in Patients with ST-Elevation Myocardial Infarction
In this study mean age of study population was 51.8±9.8, male patients were predominant (79.0%). Among the studied patients, highest percentage had history of smoking followed by hypertension, diabetes mellitus and family history of CAD in Group I patients. It was found that DM and family history of CAD and history of stroke/TIA were significantly higher in Group I than Group II. An increasing trend of SYNTAX score was observed according to the CHA₂DS₂-VASc-HSF score. SYNTAX score was significantly higher in CHA2DS2-VASc-HSF score ≥4 than CHA₂DS₂-VASc-HSF score <4 (26.3±6.3 vs. 12.1±7.7, p<0.001). Patien...
Source: Atherosclerosis - April 1, 2023 Category: Cardiology Authors: M A Rahim M J Uddin J Jahan T A Chowdhury A Momen M M Islam M A Rahman P Bala A Mamun F Chowdhury A R Majumder Source Type: research
Effect of PCSK9 inhibition in combination with statin therapy on intracranial atherosclerotic stenosis: A high-resolution MRI study
This study aimed to determine the effects of PCSK9i on intracranial plaques in moderate-intensity statin-treated individuals with ICAS.METHODS: This prospective, observational study monitored the imaging and clinical outcomes of individuals with ICAS who were consecutively treated with moderate-intensity statins with or without PCSK9i. Individuals underwent monthly visits and repeat high-resolution MRI (HR-MRI) at week 12. The primary outcome was a change in HR-MRI after 12 weeks of treatment and the secondary outcome was major vascular events during follow-up.RESULTS: Forty-nine individuals were studied (PCSK9i group: 26 ...
Source: Atherosclerosis - March 27, 2023 Category: Cardiology Authors: Lingshan Wu Qianqian Kong Hao Huang Shabei Xu Wensheng Qu Ping Zhang Zhiyuan Yu Xiang Luo Source Type: research
