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Specialty: Neurology
Condition: Diabetes
Education: Study

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Total 1259 results found since Jan 2013.

Prevalence and In-hospital outcomes of diabetes among acute ischemic stroke patients in china: results from the Chinese Stroke Center Alliance
ConclusionDiabetes was highly prevalent among AIS patients in China and associated with worse in-hospital outcomes. Greater efforts to increase targeted approach to secondary prevention treatments of diabetes in AIS patients are warranted.
Source: Journal of Neurology - May 5, 2022 Category: Neurology Source Type: research

Pattern and Severity of Leukoaraiosis and Microvascular Resistance- Inputs from a TCD Study from South Asia
Conclusions: Our study confirms the correlation of Pulsatility Index with leukoaraiosis in South-Asian patients. Interestingly, changes in microvascular resistance appeared to be similar for both periventricular and deep white matter leukoaraiosis in spite of potential differences in etiopathogenesis.
Source: Neurology India - May 3, 2022 Category: Neurology Authors: Dhing H Kumar Saraf U Umesh Maniangatt C Sinchu Kumar Savith Sankara P Sarma Sukumaran Sajith Source Type: research

Post-Stroke Administration of L-4F Promotes Neurovascular and White Matter Remodeling in Type-2 Diabetic Stroke Mice
Patients with type 2 diabetes mellitus (T2DM) exhibit a distinct and high risk of ischemic stroke with worse post-stroke neurovascular and white matter (WM) prognosis than the non-diabetic population. In the central nervous system, the ATP-binding cassette transporter member A 1 (ABCA1), a reverse cholesterol transporter that efflux cellular cholesterol, plays an important role in high-density lipoprotein (HDL) biogenesis and in maintaining neurovascular stability and WM integrity. Our previous study shows that L-4F, an economical apolipoprotein A member I (ApoA-I) mimetic peptide, has neuroprotective effects via alleviati...
Source: Frontiers in Neurology - April 28, 2022 Category: Neurology Source Type: research

Current Trends in the Animal Models for Screening of Nootropic Agents
CONCLUSION: Since a variety of etiologies can affect the cognitive processes, hence a nootropic agent may be screened in a variety of disease models. The most widely used and appropriate method to assess cognition would be by combining the behavioral and biochemical assays so that a more comprehensive profile about the nootropic effects of a drug can be elicited.PMID:35469584 | DOI:10.2174/2772432817666220425121323
Source: Epilepsy Curr - April 26, 2022 Category: Neurology Authors: Shubhima Grover Seema Jain Source Type: research

Diabetes: Chronic Metformin Treatment and Outcome Following Acute Stroke
ConclusionSimilar to previous reports, our study shows that diabetes adversely affects stroke outcome. The use of prior metformin is associated with better outcome in patients with ischemic stroke and results in lower mortality. The positive effects of metformin require further research to better understand its mechanism.
Source: Frontiers in Neurology - April 26, 2022 Category: Neurology Source Type: research

Trends in the Incidence and Risk Factors of Pregnancy-Associated Stroke
The objective of this review is to summarize studies on time trends of PAS in relation to trends in the prevalence of stroke risk factors in pregnant women. Seven retrospective national healthcare register-based cohort studies from the US, Canada, UK, Sweden, and Finland were identified. Five studies from the US, Canada, and Finland reported an increasing trend of PAS. Potential biases include more sensitive diagnostics and improved stroke awareness among pregnant women and professionals toward the end of the study period. However, the concurrent increase in the prevalence of several stroke risk factors among pregnant wome...
Source: Frontiers in Neurology - April 11, 2022 Category: Neurology Source Type: research

Analysis of prognostic risk factors for ischaemic stroke in China: A multicentre retrospective clinical study-a national survey in China
CONCLUSIONS: Our study identified sex differences in stroke-related disability, recurrence, and death and attempted to explain the causes of these differences. Our study clearly showed that a large proportion of this difference can be attributed to age, socioeconomic factors, lifestyle habits and medical history, which are confounded by sex, rather than sex per se.PMID:35362370 | DOI:10.2174/1567202619666220331160024
Source: Current Neurovascular Research - April 1, 2022 Category: Neurology Authors: Yuting Cao Ying Chen Xiaoli Li Yongjun Wang Source Type: research