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Condition: Dermatitis
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Total 8248 results found since Jan 2013.
Effects of elimination diets and clinical findings on mothers' anxiety in infants with food allergy with non-life-threatening reactions
Conclusions. The state anxiety and trait anxiety of the mothers of the infants with FA were higher than the control group, and the state anxiety scores were higher especially in the mothers of infants with FPIAP and multiple food elimination.PMID:34797040 | DOI:10.23822/EurAnnACI.1764-1489.237
Source: European Annals of Allergy and Clinical Immunology - November 19, 2021 Category: Allergy & Immunology Authors: O Sancakli A Ak ın Aslan Source Type: research
Taiwan guidelines for the diagnosis and management of pediatric atopic dermatitis: Consensus statement of the Taiwan Academy of Pediatric Allergy, Asthma and Immunology
J Microbiol Immunol Infect. 2022 Apr 20:S1684-1182(22)00051-2. doi: 10.1016/j.jmii.2022.03.004. Online ahead of print.ABSTRACTAtopic dermatitis (also known as atopic eczema) is a chronic relapsing inflammatory skin disease commonly seen in children, with increasing prevalence over the past few decades in many countries including Taiwan. The management of pediatric atopic dermatitis can be challenging, particularly as treatment options are expanding with the emergence of novel systemic and topical anti-inflammatory medications in recent years. The Taiwan Academy of Pediatric Allergy, Asthma and Immunology (TAPAAI) has devel...
Source: Journal of Microbiology, Immunology, and Infection - April 29, 2022 Category: Microbiology Authors: Tsung-Chieh Yao I-Jen Wang Hai-Lun Sun Liang-Shiou Ou Hsin-Hui Yu Lin Wang Chih-Hsing Hung Committee of the Taiwan Academy of Pediatric Allergy, Asthma and Immunology Source Type: research
Epithelial barrier regulation, antigen sampling, and food allergy
Food allergy is often associated with development of atopic dermatitis. Atopic dermatitis is a chronic inflammatory skin condition with a strong association with skin barrier gene mutations. Loss-of-function mutations in skin barrier genes increase transepidermal water loss. Also, reduction of the skin barrier can be mediated by environmental exposures. In preclinical studies of mice with skin barrier disruption, exposure to allergens on the skin induces food allergy. Exposure to food allergens on the skin with coexposure of the skin to other environmental factors induces signals in the skin for activation of food allergy,...
Source: Journal of Allergy and Clinical Immunology - September 1, 2022 Category: Allergy & Immunology Authors: Joan M. Cook-Mills, Lauren N. Emmerson Tags: Review article Source Type: research
Exploring the Heterogeneity of IgE-Mediated Food Allergy through Latent Class Analysis
In this study, we aimed to investigate distinct subgroups among patients with FAs using data from 524 children/adolescents.Methods: 524 patients with IgE-mediated FA (353 male [67%]; median age 4.4 years [IQR:3.0 –6.8]), 354 (68%) had multiple FA. The history of AD, asthma, AR, and anaphylaxis was recorded in 59.4%, 35.5%, 24.2%, and 51.2% of the patients, respectively. Latent class analysis was carried out to distinguish clinical FA phenotypes using five potential markers of allergy severity (single/multi ple FA, never/inactive/current asthma and AD, AR, and anaphylaxis).Results: Three distinct phenotypes were identifie...
Source: International Archives of Allergy and Immunology - December 5, 2022 Category: Allergy & Immunology Source Type: research
Thymic stromal lymphopoietin rather than IL-33 drives food allergy after epicutaneous sensitization to food allergen
It is increasingly recognized that one of the major routes of sensitization to food allergens is through an impaired skin barrier.1,2 Accordingly, associations between altered skin barrier and/or atopic dermatitis (AD) and food allergy have been reported.1,2 Food allergy is dependent on accumulation of intestinal mast cells and allergen-specific IgE-mediated mast cell degranulation.3,4 Mechanistically, IL-33 and thymic stromal lymphopoietin (TSLP) have both been proposed to mediate sensitization to food allergen, accumulation of intestinal mast cells, and development of food allergy, albeit in different animal models.
Source: Journal of Allergy and Clinical Immunology - March 3, 2023 Category: Allergy & Immunology Authors: Eric B. Brandt, Brandy P. Ruff, Alyssa L. Filuta, Wan-Chi Chang, Dana Shik, Gurjit K. Khurana Hershey Tags: Brief report Source Type: research
Mislabelled cow's milk allergy in infants: a prospective cohort study
Conclusions
Mislabelled CMA typically presents within the first 3 months of life involving a single organ. Infant AD and higher parental academic education are associated with mislabelled reactions. Better parental and physician awareness of the importance of objectively diagnosing milk allergy is required to avoid mislabelling of infants as being allergic to cow's milk and to prevent potential nutritional deficiencies.
Source: Archives of Disease in Childhood - May 9, 2013 Category: Pediatrics Authors: Elizur, A., Cohen, M., Goldberg, M. R., Rajuan, N., Katz, Y. Tags: Epidemiologic studies, Immunology (including allergy), Dermatology Original article Source Type: research
Filaggrin gene mutation associations with peanut allergy persist despite variations in peanut allergy diagnostic criteria or asthma status
Recently, our research team found a strong and significant association between loss-of-function (LOF) mutations in filaggrin (FLG), a gene that encodes a skin barrier protein, in European and Canadian individuals with peanut allergy (PA). These mutations result in a barrier defect and have been associated with atopic dermatitis, asthma, and allergic rhinitis. This finding represents the strongest genetic risk factor found to date for PA, a highly heritable disease, with an estimated odds ratio (OR) between 1.9 (Canadian) and 5.3 (English, Dutch, and Irish combined). Because there is no uniformly accepted definition of PA s...
Source: Journal of Allergy and Clinical Immunology - May 20, 2013 Category: Allergy & Immunology Authors: Yuka Asai, Celia Greenwood, Peter R. Hull, Reza Alizadehfar, Moshe Ben-Shoshan, Sara J. Brown, Linda Campbell, Deborah L. Michel, Johanne Bussières, François Rousseau, T. Mary Fujiwara, Kenneth Morgan, Alan D. Irvine, W.H. Irwin McLean, Ann Clarke Tags: Letters to the Editor Source Type: research
