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Potential Applications of Remote Limb Ischemic Conditioning for Chronic Cerebral Circulation Insufficiency
Conclusion Due to its long-term and often invisible course, CCCI has received less attention than acute cerebral ischemic stroke. However, without appropriate intervention, CCCI may lead to a variety of adverse events. Because the pathophysiological changes associated with CCCI are complex, pharmacological research in this area has been disappointing. Recent research suggests that RLIC, which is less invasive and more well-tolerated than drug treatment, can activate endogenous protective mechanisms during CCCI. In the present report, we reviewed studies related to CCCI (Table 1), as well as those related to stroke and sta...
Source: Frontiers in Neurology - May 2, 2019 Category: Neurology Source Type: research

Periprocedural Hemodynamic Depression Is Associated With a Higher Number of New Ischemic Brain Lesions After Stenting in the International Carotid Stenting Study-MRI Substudy Clinical Sciences
Conclusions— In patients treated by CAS, periprocedural hemodynamic depression is associated with an excess of new ischemic lesions on diffusion-weighted imaging. The findings support the hypothesis that hypoperfusion increases the susceptibility of the brain to embolism. Clinical Trial Registration— URL: http://www.controlled-trials.com. Unique identifier: ISRCTN25337470.
Source: Stroke - December 23, 2013 Category: Neurology Authors: Altinbas, A., Algra, A., Bonati, L. H., Brown, M. M., Kappelle, L. J., de Borst, G. J., Hendrikse, J., van der Tweel, I., van der Worp, H. B., on behalf of the ICSS Investigators Tags: Carotid Stenosis, Computerized tomography and Magnetic Resonance Imaging, Primary and Secondary Stroke Prevention, Carotid endarterectomy, Angioplasty and Stenting Clinical Sciences Source Type: research

Hemodynamic depression in carotid artery stent without angioplasty.
CONCLUSION. The incidence of hemodynamic depression is low when carotid stenting procedure is performed without balloon angioplasty. The incidence of neurological complications post procedure was also low. This report highlights the need for performing randomized trials comparing both techniques. PMID: 23400646 [PubMed - in process]
Source: Revista de Neurologia - February 16, 2013 Category: Neurology Authors: Garcia-Nielsen L, Carreira JM, Rabellino M, Baldi S, Zander T, Gude F, Pumar JM, Maynar-Moliner M Tags: Rev Neurol Source Type: research