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Strain Differences in Fatigue and Depression after Experimental Stroke
Abstract Fatigue and depression are common symptoms after stroke. Animal models of poststroke fatigue (PSF) and poststroke depression (PSD) would facilitate the study of these symptoms. Spontaneous locomotor activity is as an objective measure of fatigue and learned helplessness an accepted correlate of depression. We used different rat strains to evaluate stroke-induced changes in behavior in hopes that interstrain differences would provide insights into the biological basis of these symptoms. Male Lewis, Wistar, and Sprague–Dawley (SD) rats underwent experimental stroke. Spontaneous activity was assessed cont...
Source: Translational Stroke Research - October 1, 2014 Category: Neurology Source Type: research

Do family-oriented interventions reduce poststroke depression? A systematic review and recommendations for practice.
CONCLUSION: Family-oriented stroke rehabilitation may reduce depression in stroke survivors and their family caregivers. More research is required to clarify the effectiveness, feasibility, and acceptability of working with families and patients living with or who may be at risk of PSD. PMID: 25816867 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 28, 2015 Category: Neurology Authors: Vallury KD, Jones M, Gray R Tags: Top Stroke Rehabil Source Type: research

TALOS: a multicenter, randomized, double‐blind, placebo‐controlled trial to test the effects of citalopram in patients with acute stroke
DiscussionSSRI treatment is well tolerated and overall beneficial in the wake of stroke; it may also be neuroprotective and prevent new vascular events.
Source: International Journal of Stroke - April 8, 2015 Category: Neurology Authors: Kristian Lundsgaard Kraglund, Janne Kaergaard Mortensen, Erik Lerkevang Grove, Søren Paaske Johnsen, Grethe Andersen Tags: Protocol Source Type: research

Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue Following Stroke practice guidelines, update 2015
Every year, approximately 62 000 people with stroke and transient ischemic attack are treated in Canadian hospitals, and the evidence suggests one‐third or more will experience vascular‐cognitive impairment, and/or intractable fatigue, either alone or in combination. The 2015 update of the Canadian Stroke Best Practice Recommendations: Mood, Cognition and Fatigue Module guideline is a comprehensive summary of current evidence‐based recommendations for clinicians in a range of settings, who provide care to patients following stroke. The three consequences of stroke that are the focus of the this guideline (poststrok...
Source: International Journal of Stroke - June 29, 2015 Category: Neurology Authors: Gail A. Eskes, Krista L. Lanctôt, Nathan Herrmann, Patrice Lindsay, Mark Bayley, Laurie Bouvier, Deirdre Dawson, Sandra Egi, Elizabeth Gilchrist, Theresa Green, Gord Gubitz, Michael D. Hill, Tammy Hopper, Aisha Khan, Andrea King, Adam Kirton, Paige Moorh Tags: Guidelines Source Type: research

Characteristics of functional and organic stroke mimics
Conclusion Both functional and medical stroke mimics appear to have distinct features that could aid the diagnostic process.
Source: Journal of Neurology, Neurosurgery and Psychiatry - October 14, 2015 Category: Neurosurgery Authors: Gargalas, S., David, A., Khan-Bourne, N., Shotbolt, P., Weeks, R. Tags: Long term care, Immunology (including allergy), Headache (including migraine), Pain (neurology), Stroke, Memory disorders (psychiatry) ABN abstracts 2015 ABN Annual Meeting, 10 September 2015, Institute of Education, London Source Type: research

Guidelines for Adult Stroke Rehabilitation and Recovery: A Guideline for Healthcare Professionals From the American Heart Association/American Stroke Association AHA/ASA Guideline
Conclusions— As systems of care evolve in response to healthcare reform efforts, postacute care and rehabilitation are often considered a costly area of care to be trimmed but without recognition of their clinical impact and ability to reduce the risk of downstream medical morbidity resulting from immobility, depression, loss of autonomy, and reduced functional independence. The provision of comprehensive rehabilitation programs with adequate resources, dose, and duration is an essential aspect of stroke care and should be a priority in these redesign efforts. (Stroke.2016;47:e98-e169. DOI: 10.1161/STR.0000000000000098.)
Source: Stroke - May 22, 2016 Category: Neurology Authors: Winstein, C. J., Stein, J., Arena, R., Bates, B., Cherney, L. R., Cramer, S. C., Deruyter, F., Eng, J. J., Fisher, B., Harvey, R. L., Lang, C. E., MacKay-Lyons, M., Ottenbacher, K. J., Pugh, S., Reeves, M. J., Richards, L. G., Stiers, W., Zorowitz, R. D., Tags: AHA/ASA Guideline Source Type: research

Poststroke agitation and aggression and social quality of life: a case control study.
CONCLUSION: In this study sample, agitation/aggression was preponderantly of the passive type and was associated with poorer HRQoL independently from depression or medical conditions. Patients with both passive and active agitation/aggression had lower Quality of Life (QoL) than patients with only passive agitation/aggression. The causality of the association between low QoL and agitation/aggression needs to be explored in future studies. PMID: 27603431 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - September 6, 2016 Category: Neurology Authors: Lau CG, Tang WK, Liu XX, Liang HJ, Liang Y, Wong A, Mok V, Ungvari GS, Wong KS, Kim JS, Paradiso S Tags: Top Stroke Rehabil Source Type: research

Patient outcomes up to 15 years after stroke: survival, disability, quality of life, cognition and mental health
Conclusions One in five people live at least 15 years after a stroke and poor functional, cognitive and psychological outcomes affect a substantial proportion of these long-term survivors. As the global population of individuals with cardiovascular long-term conditions grows, research and health services will need to increasingly focus on preventing and managing the long-term consequences of stroke.
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 12, 2016 Category: Neurosurgery Authors: Crichton, S. L., Bray, B. D., McKevitt, C., Rudd, A. G., Wolfe, C. D. A. Tags: JNNP Patients' choice, Long term care, Stroke, Memory disorders (psychiatry) Cerebrovascular disease Source Type: research

Post Stroke Fatigue in African/Caribbean Americans: Role of Stroke Severity, Depression, and Quality of Life (P5.289)
Conclusions:In this African/Caribbean American population, higher QoL was associated with lower rates of PSF. Our data suggest that, in this minority population, self-viewed QoL may influence the risk of developing of PSF.Disclosure: Dr. Ahmed has nothing to disclose. Dr. Singer has nothing to disclose. Dr. Stefanov has nothing to disclose. Dr. Balucani has nothing to disclose. Dr. Toy has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Law has nothing to disclose. Dr. Levine has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Ahmed, A., Singer, J., Stefanov, D., Balucani, C., Toy, G., Huang, A., Law, S., Levine, S. Tags: Stroke Recovery and Rehabilitation Source Type: research

Gender Differences in Post Stroke Fatigue (P5.290)
Conclusions:In our urban predominately minority cohort, women had more severe PSF than men. The basis for the protective effect of HTN on PSF severity is unclear and deserves further study.Disclosure: Dr. Balucani has nothing to disclose. Dr. Gilles has nothing to disclose. Dr. Singer has nothing to disclose. Dr. Stefanov has nothing to disclose. Dr. Halket has nothing to disclose. Dr. Mlastabi has nothing to disclose. Dr. Huang has nothing to disclose. Dr. Weingast has nothing to disclose. Dr. Levine has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Balucani, C., Gilles, N., Singer, J., Stefanov, D., Halket, D., Mlastabi, J., Huang, A., Weingast, S., Levine, S. Tags: Stroke Recovery and Rehabilitation Source Type: research

Excessive Daytime Sleepiness and Depression in Stroke Survivors (P5.292)
Conclusions:The presence of EDS is associated with moderate to severe depression in stroke survivors. This is not related solely to SDB symptoms. Patients with fatigue and EDS should be screened for depression. Future studies are also needed to explore the role that SDB plays in this relationship.Disclosure: Dr. Pham has nothing to disclose. Dr. Sharrief has nothing to disclose. Dr. Savitz has received research support from the NIH. Dr. Sarraj has nothing to disclose. Dr. Fournier has nothing to disclose. Dr. Vahidy has nothing to disclose.
Source: Neurology - April 17, 2017 Category: Neurology Authors: Pham, Q., Sharrief, A., Savitz, S., Sarraj, A., Fournier, L., Vahidy, F. Tags: Stroke Recovery and Rehabilitation Source Type: research

Validity and reliability of the fatigue impact scale in stroke
CONCLUSION: FIS is a valid and reliable multidimensional scale that sensitively discriminated fatigue in the stroke patients from that in the control subjects.PMID:34542023 | DOI:10.1080/10749357.2021.1978629
Source: Topics in Stroke Rehabilitation - September 20, 2021 Category: Neurology Authors: Elif Balevi Batur Ozden Ozyemis çi-Taskiran Selcen Yuksel Mustafa Cengiz Gulcin Kaymak Karatas Source Type: research