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Condition: Depression

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Correlates of Post-traumatic Stress Disorder in Stroke Survivors
Conclusions: In this racially and ethnically diverse cohort of stroke and TIA survivors, stroke-induced PTSD was associated with younger age, recurrent strokes, greater disability, and comorbidities. PTSD was associated with a substantially increased physical, mental, and quality of life burden in this already vulnerable population. Having social support was protective, suggesting a potential target for intervention.
Source: Journal of Stroke and Cerebrovascular Diseases - October 21, 2013 Category: Neurology Authors: Judith Z. Goldfinger, Donald Edmondson, Ian M. Kronish, Kezhen Fei, Revathi Balakrishnan, Stanley Tuhrim, Carol R. Horowitz Tags: Original Articles Source Type: research

Rate of Stroke Death after Depression: A 40-year Longitudinal Study Extension of Chichester/Salisbury Catchment Area Study
Conclusions: These findings suggest that the identification of depressive symptoms at younger ages may have an impact on the primary prevention of stroke in later life. The notion that depression has stronger effects over a long period is consistent with a view that severe clinical depression and physical illness occur concurrently, one exacerbating the other, and health is degraded through slow-acting, cumulative processes. Data were unavailable for the type of stroke or the health-risk behaviors (smoking, diet, and so forth) in the cohort which constituted a limitation of the study. Neither is it known what proportion of...
Source: Journal of Stroke and Cerebrovascular Diseases - June 23, 2014 Category: Neurology Authors: Wendy Thomson Tags: Original Articles Source Type: research

Depression in context of low neuroticism is a risk factor for stroke: A 9-year cohort study
Conclusions: In persons without preexistent cardiac disease, depression is only predictive for future stroke in absence of high neuroticism. This might be explained by the hypothesis that late-life depression in context of low neuroticism is a marker of subclinical vascular disease.
Source: Neurology - November 3, 2014 Category: Neurology Authors: Marijnissen, R. M., Wouts, L., Schoevers, R. A., Bremmer, M. A., Beekman, A. T. F., Comijs, H. C., Oude Voshaar, R. C. Tags: All Cerebrovascular disease/Stroke ARTICLE Source Type: research

Explanatory factors for the increased mortality of stroke patients with depression
Conclusion: Depression after stroke is associated with higher mortality, particularly among younger patients. Stroke survivors taking SSRIs have an increased mortality. The association between depression and mortality is not explained by other individual medical factors.
Source: Neurology - November 24, 2014 Category: Neurology Authors: Ayerbe, L., Ayis, S., Crichton, S. L., Rudd, A. G., Wolfe, C. D. A. Tags: All Cerebrovascular disease/Stroke, Depression, Cohort studies ARTICLE Source Type: research

Long-term disability after lacunar stroke: Secondary prevention of small subcortical strokes
Conclusions: In lacunar stroke patients, older age was associated with worsening long-term disability, even without recurrence. Worse long-term function was associated with diabetes, cognitive status, and prior stroke, and regional differences may be attributable to variations in health care delivery or scale interpretation.
Source: Neurology - March 9, 2015 Category: Neurology Authors: Dhamoon, M. S., McClure, L. A., White, C. L., Lakshminarayan, K., Benavente, O. R., Elkind, M. S. V., On behalf of the SPS3 Investigators Tags: All Cerebrovascular disease/Stroke, All Rehabilitation, All epidemiology ARTICLE Source Type: research

Post-stroke fatigue: new evidence of a possible biological cause
Impaired corticomotor excitability might contribute to the aetiology of post-stroke fatigue, and provide a biological target for treatment. Fatigue after stroke affects around 40% of stroke survivors and is one of the most distressing post-stroke symptoms.1 It may resolve spontaneously over time, but for many patients, it remains a persistent and disabling problem. There are no effective treatments. Stroke survivors, caregivers and health professionals have rated fatigue as one of the top 10 priorities for stroke research.2 Some stroke survivors report that fatigue starts at the time of the stroke, and that the nature of f...
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 14, 2015 Category: Neurosurgery Authors: Mead, G. E. Tags: Long term care, Pain (neurology), Stroke, Mood disorders (including depression) Editorial commentaries Source Type: research

Stroke Induces Prolonged Changes in Lipid Metabolism, the Liver and Body Composition in Mice
AbstractDuring recovery, stroke patients are at risk of developing long-term complications that impact quality of life, including changes in body weight and composition, depression and anxiety, as well as an increased risk of subsequent vascular events. The aetiologies and time-course of these post-stroke complications have not been extensively studied and are poorly understood. Therefore, we assessed long-term changes in body composition, metabolic markers and behaviour after middle cerebral artery occlusion in mice. These outcomes were also studied in the context of obesity, a common stroke co-morbidity proposed to prote...
Source: Translational Stroke Research - December 20, 2019 Category: Neurology Source Type: research

Effect of mood on long-term disability in younger stroke survivors: results from the Psychosocial Outcomes In StrokE (POISE) study
Conclusions: Post-stroke anxiety has an adverse effect on disability at one year among young stroke survivors.PMID:34018471 | DOI:10.1080/10749357.2021.1922802
Source: Topics in Stroke Rehabilitation - May 21, 2021 Category: Neurology Authors: C Liang A J Van Laar Veth Q Li D Zheng M L Hackett Source Type: research

Burden, anxiety and depressive symptoms in partners - course and predictors during the first two years after stroke
CONCLUSIONS: Burden, anxiety and depressive symptoms are interrelated and become chronic in partners of patients with stroke. It is important to screen partners early after stroke to identify partners who are at risk for negative outcomes.PMID:35852093 | DOI:10.1080/10749357.2022.2098898
Source: Topics in Stroke Rehabilitation - July 19, 2022 Category: Neurology Authors: Vincent C M Cox Jennifer J E Welten Vera P M Schepers Marjolijn Ketelaar Willeke J Kruithof Caroline M van Heugten Johanna M A Visser-Meily Source Type: research

Health literacy is associated with less depression symptoms, higher perceived recovery, higher perceived participation, and walking ability one year after stroke - a cross-sectional study
CONCLUSION: The association between health literacy and mental, physical, and social functioning 12-months post-discharge suggests that health literacy is an important factor to consider in post-stroke rehabilitation. Longitudinal studies of health literacy in people with stroke are warranted to explore the underlying reasons for these associations.PMID:36803670 | DOI:10.1080/10749357.2023.2178133
Source: Topics in Stroke Rehabilitation - February 21, 2023 Category: Neurology Authors: Maria Flink Sebastian Lindblom Lena von Koch Axel C Carlsson Charlotte Ytterberg Source Type: research