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Specialty: Cardiology
Condition: Cholesterol

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Total 2240 results found since Jan 2013.

Cardiovascular Health in American Indians and Alaska Natives: A Scientific Statement From the American Heart Association.
CONCLUSIONS: Prevention and treatment of CVD in American Indians and Alaska Natives should focus on control of risk factors and community-based interventions that address social determinants of health, particularly among individuals with diabetes mellitus. Accurate reporting of race/ethnicity is encouraged to address race-specific risk factors. PMID: 32460555 [PubMed - as supplied by publisher]
Source: Circulation - May 27, 2020 Category: Cardiology Authors: Breathett K, Sims M, Gross M, Jackson EA, Jones EJ, Navas-Acien A, Taylor H, Thomas KL, Howard BV, American Heart Association Council on Epidemiology and Prevention; Council on Quality of Care and Outcomes Research; Council on Cardiovascular and Stroke Nu Tags: Circulation Source Type: research

Cardiovascular/stroke risk prevention: A new machine learning framework integrating carotid ultrasound image-based phenotypes and its harmonics with conventional risk factors.
CONCLUSION: The AtheroRisk-integrated ML system outperforms the AtheroRisk-conventional ML system using RF classifier. PMID: 32861380 [PubMed - in process]
Source: Indian Heart J - June 30, 2020 Category: Cardiology Authors: Jamthikar A, Gupta D, Khanna NN, Saba L, Laird JR, Suri JS Tags: Indian Heart J Source Type: research

720 Characterisation of Recent Trends in Cardiovascular Risk Factors in Young Patients With Ischaemic Stroke
Strokes in the young are associated with a disproportionately large economic and social impact in addition to their clinical effects. Standard Modifiable Cardiovascular Risk Factors (SMuRFs; hypercholesterolaemia, hypertension, diabetes and smoking) are key drivers of cardiovascular disease including strokes, however recent temporal trends in the young stroke population have not been characterised. We aimed to evaluate recent trends of SMuRFs in a cohort of young patients with ischaemic stroke.
Source: Heart, Lung and Circulation - November 8, 2020 Category: Cardiology Authors: A. Bhat, D. Makarious, V. Mahajan, Y. Husen, E. Tan, C. Burdusel, G. Gan, L. Lee, C. Chow, T. Tan Source Type: research

High Triglycerides Up CV Risk After Atherothrombotic Stroke High Triglycerides Up CV Risk After Atherothrombotic Stroke
A new study shows higher risk for further cardiovascular events and strokes in patients with a recent stroke of atherothrombotic origin and raised triglyceride levels, even accounting for statin use.Medscape Medical News
Source: Medscape Cardiology Headlines - March 23, 2022 Category: Cardiology Tags: Cardiology News Source Type: news

Medical Management Best for Atherosclerotic Stroke: AAN Medical Management Best for Atherosclerotic Stroke: AAN
An advisory from the American Academy of Neurology on preventing recurrent stroke in symptomatic intracranial atherosclerosis recommends antiplatelets and statins but advises against stenting.Medscape Medical News
Source: Medscape Cardiology Headlines - March 24, 2022 Category: Cardiology Tags: Cardiology News Source Type: news

PCSK9 inhibition in patients with acute stroke and symptomatic intracranial atherosclerosis: protocol for a prospective, randomised, open-label, blinded end-point trial with vessel-wall MR imaging
BMJ Open. 2022 Apr 29;12(4):e060068. doi: 10.1136/bmjopen-2021-060068.ABSTRACTINTRODUCTION: Dual antiplatelet therapy and high-intensity statins are the mainstay treatment in patients with acute stage, symptomatic intracranial atherosclerotic stenosis (ICAS). Alirocumab is a monoclonal antibody that can inhibit proprotein convertase subtilisin-kexin type 9 and effectively lower low-density lipoprotein cholesterol levels with less side effects than statins. We hypothesise that alirocumab treatment in addition to statin therapy could stabilise intracranial plaque and reduce arterial stenosis.METHODS AND ANALYSIS: In this pro...
Source: Atherosclerosis - April 29, 2022 Category: Cardiology Authors: Yen-Chu Huang Chia-Hao Chang Yuan-Hsiung Tsai Hsu-Huei Weng Leng-Chieh Lin Jiann-Der Lee Source Type: research

Markers of early vascular aging are not associated with cryptogenic ischemic stroke in the young: A case-control study
CONCLUSIONS: Higher CIMT and PWV were associated to higher age, male sex, and several well-documented cardiovascular risk factors. However, in this study we could not prove that either covert atherosclerosis or arterial stiffness contribute to pathogenesis of early-onset CIS.PMID:35849915 | DOI:10.1016/j.jstrokecerebrovasdis.2022.106647
Source: Atherosclerosis - July 19, 2022 Category: Cardiology Authors: Nicolas Martinez-Majander Daniel Gordin Lotta Joutsi-Korhonen Titta Salopuro Krishna Adeshara Gerli Sibolt Sami Curtze Jani Pirinen Ron Liebkind Lauri Soinne Tiina Sairanen Satu Suihko Mika Lehto Juha Sinisalo Per-Henrik Groop Turgut Tatlisumak Jukka Puta Source Type: research

Non-traditional lipid parameters as potential predictors of carotid plaque vulnerability and stenosis in patients with acute ischemic stroke
CONCLUSION: This study provides evidence that non-traditional lipid parameters (LP-C, non-HDL-C/HDL-C, non-HDL-C, CRI-I, and CRI-II) were potential predictors of carotid plaque vulnerability in patients with AIS. However, no significant correlation was observed between TG/HDL-C and AIP. RLP-C, non-HDL-C/HDL-C, non-HDL-C, TG/HDL-C, CRI-I, CRI-II, and AIP were closely related to the degree of carotid plaque stenosis. Non-traditional lipid parameters can be used as novel biomarkers of carotid plaque vulnerability and stenosis.PMID:36301362 | DOI:10.1007/s10072-022-06472-3
Source: Atherosclerosis - October 27, 2022 Category: Cardiology Authors: Zhao Zhao Huanru Wang Qian Hou Youting Zhou Yanchun Zhang Source Type: research

Differential association between apolipoprotein B and LDL cholesterol and cerebral atherosclerosis according to pre-stroke statin use
CONCLUSIONS: ApoB was consistently associated with ICAS, particularly symptomatic stenosis, in both statin-naïve and statin-treated patients. The close association between ApoB levels and residual risk in statin-treated patients could be partially explained by these results.PMID:36966561 | DOI:10.1016/j.atherosclerosis.2023.03.014
Source: Atherosclerosis - March 26, 2023 Category: Cardiology Authors: Minyoul Baik Hyo Suk Nam Ji Hoe Heo Hye Sun Lee Young Dae Kim Source Type: research

Effects of adjuvant berberine therapy on acute ischemic stroke: A meta-analysis
Phytother Res. 2023 Jul 8. doi: 10.1002/ptr.7920. Online ahead of print.ABSTRACTWe conducted a meta-analysis to evaluate the clinical efficacy of berberine (BBR) in treating acute ischemic stroke (AIS), explore its anti-inflammatory effects, and assess its potential applications for AIS patients. We comprehensively searched nine databases from inception until July 1, 2022, to identify clinical trials investigating the use of BBR in treating AIS. We performed statistical analyses using RevMan5.4 software and focused on primary outcomes such as inflammatory markers as well as secondary outcomes including immune system indica...
Source: Atherosclerosis - July 8, 2023 Category: Cardiology Authors: Dan Luo Baili Yu Shoukai Sun Bonan Chen Harsh Vivek Harkare Longlong Wang Jie Pan Bin Huang Yang Song Tianhong Ma Shihua Shi Source Type: research

Small dense LDL cholesterol and ischemic stroke
Background and Aims: For decades it has been suggested that small dense low-density lipoprotein (sdLDL) may be particularly atherogenic. High levels of sdLDL are associated with an increased risk of ischemic heart disease; however, the association of sdLDL with ischemic stroke has not been explored in a large prospective study on the general population. We tested the hypothesis that high sdLDL cholesterol levels are associated with an increased risk of ischemic stroke.
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: M. Balling, B. Nordestgaard, A. Varbo, A. Langsted, P. Kamstrup, S. Afzal Source Type: research

Inflammation and dyslipidaemia as the additional risk for stroke in patients with atrial fibrillation
Background and Aims: Atrial fibrillation (AF) is often accompanied by complications, especially ischemic stroke. AF is associated with atrial structural changes that may have an inflammatory basis. Dyslipidemia is the basis for the development of atherosclerotic diseases, their role in the development of AF is not entirely clear, and previous studies suggest a "cholesterol paradox". The aim of this study is to investigate the relationship between inflammation markers and dyslipidemia risk in patients with AF and stroke
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: S. Grigoryan, A. Stepanyan, P. Zelveian, L. Hazarapetyan Source Type: research

Statin Use in ICH Linked to Lower Risk for Subsequent Stroke Statin Use in ICH Linked to Lower Risk for Subsequent Stroke
Observational data suggest that use of statins after intracerebral hemorrhage is linked to lower risk for recurrent stroke. Researchers call for a randomized trial of statins in these patients.Medscape Medical News
Source: Medscape Cardiology Headlines - August 30, 2023 Category: Cardiology Tags: Cardiology News Source Type: news