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Bending the Cardiovascular Event Curve by Evaluating the Potential Impact of Achieving Low-Density Lipoprotein Cholesterol Goal Across a Large Health System Among Secondary Prevention Patients
Guidelines recommend aggressive low-density lipoprotein cholesterol (LDL-C) lowering in patients with atherosclerotic cardiovascular disease (ASCVD). However, the recommended threshold of LDL-C ≤70 mg/dL is often not achieved. We used data from the Duke University Health System electronic health record to characterize patterns of lipid levels and lipid management in patients with ASCVD to estimate the number of clinical events that could be prevented by achieving LDL-C ≤70 mg/dL . A mu ltivariable logistic regression model was developed to predict the 1-year composite of all-cause mortality, myocardial infarction, stro...
Source: The American Journal of Cardiology - November 10, 2022 Category: Cardiology Authors: Nishant P. Shah, Courtney Page, Cynthia L. Green, Michael Gao, Joanna Cavalier, Robert W. McGarrah, Tracy A. DeWald, Devdutta Sangvai, Manesh R. Patel, Neha J. Pagidipati Source Type: research

Relationship of diabetes, heart failure, and N ‐terminal pro‐B‐type natriuretic peptide with cardiovascular outcomes in patients with atrial fibrillation
ConclusionsDiabetes and HF were independently associated with an increased risk of CV death/HHF in an unselected AF patient population, and NT-proBNP improved risk assessment. These findings suggest that AF patients with diabetes and/or HF should be managed not only for their risk of stroke and systemic embolic events but also for CV death/HHF.
Source: ESC Heart Failure - May 20, 2022 Category: Cardiology Authors: Felix Hofer, Ulrike Pailer, Patrick Sulzgruber, Christian Gerges, Max ‐Paul Winter, Robert P. Giugliano, Michael Gottsauner‐Wolf, Martin Hülsmann, Niema Kazem, Lorenz Koller, Robert Schönbauer, Alexander Niessner, Christian Hengstenberg, Tags: Original Article Source Type: research

Development and Validation of Electronic Quality Measures to Assess Care for Patients With Transient Ischemic Attack and Minor Ischemic Stroke Original Articles
Conclusions— It is feasible to construct valid eQMs for processes of transient ischemic attack and minor ischemic stroke care. Healthcare systems with EHRs should consider using electronic data to evaluate care for their patients with transient ischemic attack and to complement and expand quality measurement programs currently focused on patients with stroke.
Source: Circulation: Cardiovascular Quality and Outcomes - September 14, 2017 Category: Cardiology Authors: Bravata, D. M., Myers, L. J., Cheng, E., Reeves, M., Baye, F., Yu, Z., Damush, T., Miech, E. J., Sico, J., Phipps, M., Zillich, A., Johanning, J., Chaturvedi, S., Austin, C., Ferguson, J., Maryfield, B., Snow, K., Ofner, S., Graham, G., Rhude, R., William Tags: Quality and Outcomes, Transient Ischemic Attack (TIA) Original Articles Source Type: research

Understanding Population Cardiovascular Health: Harnessing the Power of Electronic Health Records.
Abstract In 2004 the American Heart Association (AHA) set forth an ambitious strategic goal for 2010 to 1) reduce death from coronary heart disease and stroke by 25%, 2) reduce the prevalence of smoking, high cholesterol, uncontrolled hypertension, and physical inactivity by 25%, and 3) to stop increases in obesity and diabetes relative to rates in 1999. Having achieved or exceeded goals 1 and 2 by 2008 through a number of collaborative efforts, including public education, practice guidelines and quality improvement initiatives, in 2009, the AHA reframed its focus more broadly to one of achieving increased levels ...
Source: Circulation - September 1, 2015 Category: Cardiology Authors: Newby LK Tags: Circulation Source Type: research

Abstract 146: Clinical and Economic Consequences of Statin Intolerance in the U.S.: Results from an Integrated Health System Session Title: Poster Session I
Conclusion: While the majority of SI patients were on a statin, SI patients demonstrate a higher risk of some cardiovascular events; incur higher healthcare costs; and difficulty reaching LDL-C goals compared to patients without SI. Alternative treatment strategies are needed to better serve this at-risk patient population.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Sanchez, R. J., Graham, J. H., Evans, M. A., Mallya, U. G., Panaccio, M. P., Steinhubl, S. R. Tags: Session Title: Poster Session I Source Type: research

Abstract 166: Developing the Veterans Affairs Cardiac Risk Score Session Title: Poster Session I
Conclusion: We demonstrated that an EHR in a specific population could risk-stratify patients as well those from as organized cohort studies and greatly improve calibration. Further, our finding that the ASCVD score greatly underpredicted in our population, while previous work have reported the ASCVD over-predictind in other cohorts, suggests that rather than arguing about which risk tool is best, our patients may be better served by us focusing on calibrating CV risk tools for our specific patient population using their EHR data.
Source: Circulation: Cardiovascular Quality and Outcomes - April 29, 2015 Category: Cardiology Authors: Sussman, J. B., Wiitala, W., Hofer, T., Zawitowski, M., Vijan, S., Hayward, R. Tags: Session Title: Poster Session I Source Type: research

The Stroke 8: A Daily Checklist for Inpatient Stroke Management
We describe the Stroke 8 checklist, designed to be part of the daily assessment of patients hospitalized with acute stroke. It consists of 8 items classified into 3 categories as follows: (1) stroke prevention: antithrombotic use, statin use, glucose control, blood pressure control; (2) prevention of complications: deep venous thrombosis prophylaxis, temperature control; and (3) recovery and disposition: fluids and nutrition, mobility and therapy. The Stroke 8 checklist has been implemented in 3 formats over an 8-year period: laminated cards, an electronic documentation template, and an electronic template supplemented wit...
Source: Critical Pathways in Cardiology - February 17, 2015 Category: Cardiology Tags: Original Articles Source Type: research