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Specialty: Cardiology
Condition: Heart Failure
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Total 2665 results found since Jan 2013.
Suberosin Alleviates Thiazolidinedione-Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4-LPCAT3 and PI3K-AKT Signaling Pathways
In this study, we investigated the anti-ferroptosis effects of suberosin (SBR; a prenylated coumarin) in diabetic Sprague Dawley rats. Further, we assessed the effects of co-administration of SBR (30 and 90 mg/kg/day) with thiazolidinedione (TZ at 15 mg/kg) to mitigate TZ-induced cardiomyopathy in diabetic rats. Our results showed that cardiac output, stroke volume, left ventricle systolic and diastolic pressures were aggravated in diabetic rats treated with TZ alone after 4 weeks. TZ treatments induced ferroptosis as well as marked histoarchitecture disarrangements in rat cardiomyocytes. The study found that optimizing vo...
Source: Cardiovascular Toxicology - September 7, 2023 Category: Cardiology Authors: Shabnoor Iqbal Farhat Jabeen Ivan Kahwa Timothy Omara Source Type: research
Causal associations between type 1 diabetes mellitus and cardiovascular diseases: a Mendelian randomization study
CONCLUSION: This MR study provided evidence supporting the causal effect of T1DM on peripheral atherosclerosis and coronary atherosclerosis, with hypertension partly mediating this effect.PMID:37659996 | PMC:PMC10475187 | DOI:10.1186/s12933-023-01974-6
Source: Atherosclerosis - September 2, 2023 Category: Cardiology Authors: Zirui Liu Haocheng Wang Zhengkai Yang Yu Lu Cao Zou Source Type: research
Comparison of serum lipoprotein(a) levels in young and middle-aged patients presenting for the first time with ST-elevation myocardial infarction: a single-centre study
CONCLUSION: Lp(a) level was found to be a higher and a possible independent risk factor in young patients who presented with STEMI for the first time, compared to the middle-aged patient group. Lp(a) is a highly atherogenic molecule and it has been associated with stroke, heart failure, aortic stenosis, as well as coronary artery disease. Measurement of Lp(a) levels may be recommended in young patients with high cardiovascular risk.PMID:37656600 | DOI:10.5830/CVJA-2023-038
Source: Cardiovascular Journal of Africa - September 1, 2023 Category: Cardiology Authors: Song ül Usalp Emine Altunta ş Bayram Ba ğırtan Kanber Ö Karabay Source Type: research
Early Aortic Valve Replacement in Symptomatic Normal-Flow, Low-Gradient Severe Aortic Stenosis: A Propensity Score-Matched Retrospective Cohort Study
CONCLUSIONS: An early AVR strategy may be beneficial in reducing the risk of a composite outcome of death or hospitalization for HF in symptomatic patients with NFLG severe AS. Future randomized studies are required to validate and confirm our findings.PMID:37653715 | DOI:10.4070/kcj.2023.0022
Source: Korean Circulation Journal - September 1, 2023 Category: Cardiology Authors: Kyu Kim Iksung Cho Kyu-Yong Ko Seung-Hyun Lee Sak Lee Geu-Ru Hong Jong-Won Ha Chi Young Shim Source Type: research
Comparison of serum lipoprotein(a) levels in young and middle-aged patients presenting for the first time with ST-elevation myocardial infarction: a single-centre study
CONCLUSION: Lp(a) level was found to be a higher and a possible independent risk factor in young patients who presented with STEMI for the first time, compared to the middle-aged patient group. Lp(a) is a highly atherogenic molecule and it has been associated with stroke, heart failure, aortic stenosis, as well as coronary artery disease. Measurement of Lp(a) levels may be recommended in young patients with high cardiovascular risk.PMID:37656600 | DOI:10.5830/CVJA-2023-038
Source: Cardiovascular Journal of Africa - September 1, 2023 Category: Cardiology Authors: Song ül Usalp Emine Altunta ş Bayram Ba ğırtan Kanber Ö Karabay Source Type: research
Early Aortic Valve Replacement in Symptomatic Normal-Flow, Low-Gradient Severe Aortic Stenosis: A Propensity Score-Matched Retrospective Cohort Study
CONCLUSIONS: An early AVR strategy may be beneficial in reducing the risk of a composite outcome of death or hospitalization for HF in symptomatic patients with NFLG severe AS. Future randomized studies are required to validate and confirm our findings.PMID:37653715 | DOI:10.4070/kcj.2023.0022
Source: Korean Circulation Journal - September 1, 2023 Category: Cardiology Authors: Kyu Kim Iksung Cho Kyu-Yong Ko Seung-Hyun Lee Sak Lee Geu-Ru Hong Jong-Won Ha Chi Young Shim Source Type: research
Comparison of serum lipoprotein(a) levels in young and middle-aged patients presenting for the first time with ST-elevation myocardial infarction: a single-centre study
CONCLUSION: Lp(a) level was found to be a higher and a possible independent risk factor in young patients who presented with STEMI for the first time, compared to the middle-aged patient group. Lp(a) is a highly atherogenic molecule and it has been associated with stroke, heart failure, aortic stenosis, as well as coronary artery disease. Measurement of Lp(a) levels may be recommended in young patients with high cardiovascular risk.PMID:37656600 | DOI:10.5830/CVJA-2023-038
Source: Cardiovascular Journal of Africa - September 1, 2023 Category: Cardiology Authors: Song ül Usalp Emine Altunta ş Bayram Ba ğırtan Kanber Ö Karabay Source Type: research
Early Aortic Valve Replacement in Symptomatic Normal-Flow, Low-Gradient Severe Aortic Stenosis: A Propensity Score-Matched Retrospective Cohort Study
CONCLUSIONS: An early AVR strategy may be beneficial in reducing the risk of a composite outcome of death or hospitalization for HF in symptomatic patients with NFLG severe AS. Future randomized studies are required to validate and confirm our findings.PMID:37653715 | DOI:10.4070/kcj.2023.0022
Source: Korean Circulation Journal - September 1, 2023 Category: Cardiology Authors: Kyu Kim Iksung Cho Kyu-Yong Ko Seung-Hyun Lee Sak Lee Geu-Ru Hong Jong-Won Ha Chi Young Shim Source Type: research
