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Reduced short-term complications and mortality following Enhanced Recovery primary hip and knee arthroplasty: results from 6,000 consecutive procedures.
Abstract Background and purpose Enhanced Recovery (ER) is a well-established multidisciplinary strategy in lower limb arthroplasty and was introduced in our department in May 2008. This retrospective study reviews short-term outcomes in a consecutive unselected series of 3,000 procedures (the "ER" group), and compares them to a numerically comparable cohort that had been operated on previously using a traditional protocol (the "Trad" group). Methods Prospectively collected data on surgical endpoints (length of stay (LOS), return to theater (RTT), re-admission, and 30- and 90-day mortality) and medical complication...
Source: Acta Orthopaedica - December 20, 2013 Category: Orthopaedics Authors: Khan SK, Malviya A, Muller SD, Carluke I, Partington PF, Emmerson KP, Reed MR Tags: Acta Orthop Source Type: research

Minimally invasive direct coronary artery bypass versus off-pump coronary surgery through sternotomy.
CONCLUSIONS: MIDCAB can be performed safely in appropriately selected patients with outcomes comparable with OPCAB. The potential benefits include shorter hospital stay, reduced need for blood transfusion and faster recovery. PMID: 24112493 [PubMed - as supplied by publisher]
Source: Annals of the Royal College of Surgeons of England - October 1, 2013 Category: Surgery Authors: Birla R, Patel P, Aresu G, Asimakopoulos G Tags: Ann R Coll Surg Engl Source Type: research

110 * a biocompatible perfusion strategy is safe and is associated with excellent clinical outcomes and reduced blood transfusions in a contemporary series of patients undergoing coronary artery bypass grafting: a two-centre study
Conclusions: In a contemporary cohort of patients undergoing CABG, the use of the BPS is safe and effective. It is associated with excellent clinical outcomes and reduced allogeneic blood transfusions.
Source: Interactive CardioVascular and Thoracic Surgery - September 18, 2013 Category: Cardiovascular & Thoracic Surgery Authors: Shapira, O., Korach, A., Pinaud, F., Dabah, A., Bao, Y., Corbeau, J. J., de Brux, J. L., Baufreton, C. Tags: Cardiopulmonary bypass: Improving the outcome in marginal patients Source Type: research

Neuraxial anesthesia versus general anesthesia for urological surgery: systematic review.
CONCLUSION At the moment, the evidence available cannot prove that neuraxial anesthesia is more effective and safer than general anesthesia for urological surgery. There were insufficient data to pool the results relating to mortality, stroke, myocardial infarction, length of hospitalization, quality of life, degree of satisfaction, postoperative cognitive dysfunction and blood transfusion requirements. PMID: 23903267 [PubMed - in process]
Source: Sao Paulo Medical Journal - August 3, 2013 Category: Journals (General) Authors: Barbosa FT, Castro AA Tags: Sao Paulo Med J Source Type: research

Tranexamic acid for reducing mortality in emergency and urgent surgery.
CONCLUSIONS: There is evidence that tranexamic acid reduces blood transfusion in patients undergoing emergency or urgent surgery. There is a need for a large pragmatic clinical trial to assess the effects of routine use of tranexamic acid on mortality in a heterogeneous group of urgent and emergency surgical patients. PMID: 23440847 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - March 2, 2013 Category: Journals (General) Authors: Perel P, Ker K, Morales Uribe CH, Roberts I Tags: Cochrane Database Syst Rev Source Type: research

Rationale and Design of the On‐Treatment PLAtelet Reactivity‐Guided Therapy Modification FOR ST‐Segment Elevation Myocardial Infarction (PLATFORM) Randomized Trial
ConclusionPLATFORM will determine whether the platelet reactivity‐guided use of ticagrelor in combination with 200 mg aspirin, compared with standard antiplatelet regimen, improves clinical outcome in moderate to high‐risk STEMI patients undergoing PPCI. Clinical Trial RegistrationU.S. National Institutes of Health (NIH) at www.clinicaltrials.gov. ClinicalTrials.gov Identifier: NCT01739556, and Current Controlled Trials at www.controlledtrials.com. International Standard Randomized Controlled Trial Number ISRCTN83081599.
Source: Journal of Interventional Cardiology - December 1, 2012 Category: Cardiology Authors: IGOR MRDOVIC, LIDIJA SAVIC, GORDANA KRLJANAC, MILIKA ASANIN, NATASA CVETINOVIC, NATASA BRDAR, MILENA STOJANOVIC, NEMANJA DJURICIC, SANJA STANKOVIC, JELENA MARINKOVIC, JOVAN PERUNICIC Tags: Randomized Trial Source Type: research

Modeling anesthetic times. Predictors and implications for short-term outcomes
Conclusions: Modeling individually anesthetic induction and recovery time on the basis of operative and anesthetic procedure characteristics is feasible. Anesthetic and operative times do not impact perioperative morbidity and mortality.
Source: Journal of Surgical Research - October 31, 2012 Category: Surgery Authors: Panagiotis Kougias, Vikram Tiwari, Neal R. Barshes, Carlos F. Bechara, Briauna Lowery, George Pisimisis, David H. Berger Tags: Association for Academic Surgery Source Type: research

Transcatheter aortic valve implantation versus surgical aortic valve replacement for severe aortic stenosis: Results from an intermediate risk propensity-matched population of the Italian OBSERVANT study
Conclusions: Patients undergoing transcatheter and surgical treatment of severe aortic stenosis are still extremely distinct populations. In the relatively low-risk propensity-matched population analyzed, despite similar procedural and 30-day mortality, SAVR was associated with a higher risk for blood transfusion, whereas TAVI showed a significantly increased rate of vascular damage, permanent AV block and residual aortic valve regurgitation.
Source: International Journal of Cardiology - May 28, 2012 Category: Cardiology Authors: Paola D'Errigo, Marco Barbanti, Marco Ranucci, Francesco Onorati, Remo Daniel Covello, Stefano Rosato, Corrado Tamburino, Francesco Santini, Gennaro Santoro, Fulvia Seccareccia, on behalf of the OBSERVANT Research Group Tags: Original Articles Source Type: research

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