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Total 515 results found since Jan 2013.

How Does SARS-CoV-2 Infection Affect Survival of Emergency Cardiovascular Patients? A Cohort Study From a German Insurance Claims Database
CONCLUSION: This retrospective analysis of claims data has provided hints of an association between the COVID-19 pandemic and increased in hospital mortality in patients with acute stroke. Furthermore, confirmed SARS-CoV-2 infection was associated with increased mortality in patients with stroke, TIA, and ALI. Future studies are urgently needed to better understand the underlying mechanism and relationship between the new coronavirus and acute stroke.PMID:33824066 | DOI:10.1016/j.ejvs.2021.03.006
Source: PubMed: Eur J Vasc Endovasc ... - April 7, 2021 Category: Surgery Authors: Christian-Alexander Behrendt Moritz Seiffert Christian Gerloff Helmut L'Hoest Laura Acar G ötz Thomalla Source Type: research

Janssen Announces U.S. FDA Approval of PONVORY ™ (ponesimod), an Oral Treatment for Adults with Relapsing Multiple Sclerosis Proven Superior to Aubagio® (teriflunomide) in Reducing Annual Relapses and Brain Lesions
TITUSVILLE, N.J. – (March 19, 2021) – The Janssen Pharmaceutical Companies of Johnson & Johnson today announced that the U.S. Food and Drug Administration (FDA) approved PONVORY™ (ponesimod), a once-daily oral selective sphingosine-1-phosphate receptor 1 (S1P1) modulator, to treat adults with relapsing forms of multiple sclerosis (MS), to include clinically isolated syndrome, relapsing-remitting disease and active secondary progressive disease.1,2,3 PONVORY™ offers MS patients superior efficacy in reducing annualized relapse rates compared to an established oral therapy and a proven safety profile backed by ove...
Source: Johnson and Johnson - March 19, 2021 Category: Pharmaceuticals Tags: Innovation Source Type: news

Risk of early mortality and cardiovascular disease according to the presence of recently diagnosed diabetes and requirement for insulin treatment: A nationwide study
ConclusionsRecently diagnosed type 2 diabetes patients showed increased risks of incident CVDs and premature mortality, and insulin ‐treated group demonstrated an additional increase in the risks of these outcomes in adults with recently diagnosed type 2 diabetes, suggesting the need for intensified cardio‐protective interventions for adults with insulin‐treated type 2 diabetes.
Source: Journal of Diabetes Investigation - March 19, 2021 Category: Endocrinology Authors: You ‐Bin Lee, Kyungdo Han, Bongsung Kim, Min Sun Choi, Jiyun Park, Minyoung Kim, Sang‐Man Jin, Kyu Yeon Hur, Gyuri Kim, Jae Hyeon Kim Tags: Original Article Source Type: research

Risk of early mortality and cardiovascular disease according to the presence of recently ‐diagnosed diabetes and requirement for insulin treatment: a nationwide study
ConclusionsRecently ‐diagnosed T2D patients showed increased risks of incident CVDs and premature mortality, and insulin‐treated group demonstrated an additional increase in the risks of these outcomes in adults with recently‐diagnosed T2D, suggesting the need for intensified cardio‐protective interventions for adults with insulin‐treated T2D.
Source: Journal of Diabetes Investigation - March 4, 2021 Category: Endocrinology Authors: You ‐Bin Lee, Kyungdo Han, Bongsung Kim, Min Sun Choi, Jiyun Park, Minyoung Kim, Sang‐Man Jin, Kyu Yeon Hur, Gyuri Kim, Jae Hyeon Kim Tags: ORIGINAL ARTICLE Source Type: research

Evaluating a Simple Approach to Identify Adults Meeting the 2018 AHA/ACC Cholesterol Guideline Definition of Very High Risk for Atherosclerotic Cardiovascular Disease
ConclusionThe vast majority of patients with a recent ACS, history of MI, ischemic stroke, or symptomatic PAD meet the 2018 AHA/ACC cholesterol guideline definition of very high risk.
Source: Cardiovascular Drugs and Therapy - March 4, 2021 Category: Cardiology Source Type: research

Healthcare resource utilization and costs of major atherothrombotic vascular events among patients with peripheral artery disease after revascularization
CONCLUSION: Patients with PAD who experience major atherothrombotic vascular events post-revascularization have considerably higher healthcare resource use and costs compared with similar metrics pre-revascularization. Therefore, reducing the rate of such events could reduce overall healthcare costs for this population.PMID:33634723 | DOI:10.1080/13696998.2021.1891089
Source: Journal of Medical Economics - February 26, 2021 Category: Health Management Authors: Urvi Desai Akshay Kharat Connie N Hess Dejan Milentijevic Fran çois Laliberté Peter Zuckerman John Benson Patrick Lefebvre William R Hiatt Marc P Bonaca Source Type: research

Metabolic Syndrome Severity Score for Predicting Cardiovascular Events: A Nationwide Population-Based Study from Korea.
Conclusion: The newly developed age- and sex-specific continuous MS score for the Korean population is an independent predictor of ischemic stroke and MI in Korean middle-aged adults even after adjusting for confounding factors. PMID: 33516167 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - February 2, 2021 Category: Endocrinology Tags: Diabetes Metab J Source Type: research

Bariatric surgery may provide better protection than uvulopalatopharyngoplasty against major adverse cardiovascular events in obese patients with obstructive sleep apnea
CONCLUSION: BS may provide greater protection against MACE than UPPP in Asian obese patients with OSA. Additional mechanistic research is needed to clarify differences between BS and UPPP in these patients.PMID:33423961 | DOI:10.1016/j.soard.2020.11.018
Source: Surgery for Obesity and Related Diseases : official journal of the American Society for Bariatric Surgery - January 11, 2021 Category: Surgery Authors: Tien-Yu Chen Chien-Ting Liu Chi-Hsiang Chung Shao-Lun Hung Wu-Chien Chien Jian-Han Chen Source Type: research

Increased Risk of Cardiovascular Disease and Mortality in Patients with Diabetes and Coexisting Depression: A Nationwide Population-Based Cohort Study.
Conclusion: Coexisting depression in patients with diabetes has a deleterious effect on the development of CVD and mortality. We suggest that more attention should be given to patients with diabetes who present with depressive symptoms. PMID: 33297602 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism Journal - December 13, 2020 Category: Endocrinology Tags: Diabetes Metab J Source Type: research