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Condition: Heart Attack
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Total 334 results found since Jan 2013.

Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits
Conclusions: Lag 0–2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. https://doi.org/10.1289/EHP1545 Received: 23 December 2016 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 26 October 2017 Please address correspondence to J.Y. Abrams, Centers for Disease Control and Prevention, NCEZID/DHCPP, 1600 Clifton Rd. NE, CDC Mailstop A30, Atlanta, GA 30333 USA. Telephone: (404) 639-5121. Email: jabrams@cdc.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1545). The authors ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Antiplatelet Effect of Different Loading Doses of Ticagrelor in Patients With Non –ST-Elevation Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention: The APELOT Trial
Conclusions Doubling the ticagrelor LD achieved faster onset and greater platelet inhibition without an increase in adverse events in patients with NSTE-ACS undergoing PCI.
Source: Canadian Journal of Cardiology - December 3, 2017 Category: Cardiology Source Type: research

Invasive or Conservative Approach in Elderly Patients with Non-ST-segment Elevation Myocardial Infarction: Systematic Review and Meta-Analysis
Conclusion The “overall” benefit with “invasive” strategy comes from the data of observational studies that are prone to selection bias. We believe that there is a need for a large randomised study in the elderly patients regarding management of NSTEMI. Teaser Trials comparing invasive with conservation treatment for elderly patients presenting with NSTEMI are limited resulting in considerable variation in the management of such patients. In the current systematic review, we tried to consolidate the current evidence on these 2 modes of treatment. There was a reduction in mortality with the invasive approach. Howeve...
Source: Canadian Journal of Cardiology - December 6, 2017 Category: Cardiology Source Type: research

Temporal changes in treatments and outcomes after acute myocardial infarction among cancer survivors and patients without cancer, 1995 to 2013
CONCLUSIONSAmong CS and NCP with AMI in Ontario, similar improvements in mortality and receipt of treatments were observed between 1995 and 2013. However, compared with NCP, CS had a higher risk of mortality and heart failure. Cancer 2017. © 2017 American Cancer Society.
Source: Cancer - December 6, 2017 Category: Cancer & Oncology Authors: Inna Y. Gong, Andrew T. Yan, Dennis T. Ko, Craig C. Earle, Winson Y. Cheung, Stuart Peacock, Marlous Hall, Chris P. Gale, Kelvin K. W. Chan Tags: Original Article Source Type: research

The Divergent Cardiovascular Effects of ACE Inhibitors and ARBs in Patient With Type 2 Diabetes Mellitus
Publication date: Available online 22 December 2017 Source:Canadian Journal of Diabetes Author(s): Martin H. Strauss, Alistair S. Hall The renin angiotensin aldosterone system (RAAS) plays a central role in the pathophysiology of hypertension and vascular disease. Angiotensin-converting enzyme inhibitors (ACEi's) suppress angiotensin II (ANG II) concentrations, whereas angiotensin II type 1 (AT1) receptor blockers (ARBs) block the binding of ANG II to AT1 receptors. ACEi's and ARBs are both effective antihypertensive agents and produce similar risk reductions for stroke, a blood pressure-dependent phenomenon. ACEi's also ...
Source: Canadian Journal of Diabetes - December 22, 2017 Category: Endocrinology Source Type: research

Design of a Randomized Placebo-Controlled Trial to Assess Dabigatran and Omeprazole in Patients with Myocardial Injury after Noncardiac Surgery (MANAGE)
Conclusion MANAGE is the first randomized controlled trial to evaluate a potential treatment of patients who suffered MINS.
Source: Canadian Journal of Cardiology - February 3, 2018 Category: Cardiology Source Type: research

Long term Follow-up of the Trial of Routine ANgioplasty and Stenting after Fibrinolysis to Enhance Reperfusion in Acute Myocardial Infarction (TRANSFER AMI)
Conclusion Despite the short-term benefit and safety of an early invasive strategy in STEMI patients receiving fibrinolysis, no statistically-significant differences in MACE were observed over 7.8 years.
Source: Canadian Journal of Cardiology - February 10, 2018 Category: Cardiology Source Type: research

An Invasive vs a Conservative Approach in Elderly Patients with Non –ST-Segment Elevation Myocardial Infarction: Systematic Review and Meta-Analysis
Conclusion The overall benefit with invasive strategy comes from the data of observational studies that are prone to selection bias. We believe that there is a need for a large randomized study in the elderly patients regarding management of NSTEMI.
Source: Canadian Journal of Cardiology - February 21, 2018 Category: Cardiology Source Type: research

The potential impact of new stent platforms for coronary revascularization in diabetics
Publication date: Available online 1 March 2018 Source:Canadian Journal of Cardiology Author(s): Gustavo S. Guandalini, Sripal Bangalore Coronary artery disease in patients with diabetes mellitus (DM) is characterized by extensive atherosclerosis, longer lesions and diffuse distal disease. Consequently, these patients have worse outcomes following coronary revascularization, regardless of the modality employed. Traditionally, coronary artery bypass grafting (CABG) has been regarded as more effective than percutaneous coronary intervention (PCI) in patients with DM, owing likely to more complete revascularization and prote...
Source: Canadian Journal of Cardiology - March 2, 2018 Category: Cardiology Source Type: research

Clinical Outcomes of Plavix and Generic Clopidogrel for Patients Hospitalized With an Acute Coronary Syndrome Original Articles
Conclusions: Generic clopidogrel was noninferior to Plavix with respect to the composite end point of death and recurrent hospitalization for ACS at 1 year among adults >65 years after an ACS hospitalization. Our findings support generic clopidogrel in ACS, which could lead to substantial healthcare cost savings.
Source: Circulation: Cardiovascular Quality and Outcomes - March 13, 2018 Category: Cardiology Authors: Ko, D. T., Krumholz, H. M., Tu, J. V., Austin, P. C., Stukel, T. A., Koh, M., Chong, A., de Melo, J. F., Jackevicius, C. A. Tags: Health Services, Mortality/Survival Original Articles Source Type: research

The Divergent Cardiovascular Effects of Angiotensin-Converting Enzyme Inhibitors and Angiotensin II Type 1 Receptor Blockers in Adult Patients With Type 2 Diabetes Mellitus
Publication date: April 2018 Source:Canadian Journal of Diabetes, Volume 42, Issue 2 Author(s): Martin H. Strauss, Alistair S. Hall The renin angiotensin aldosterone system (RAAS) plays a central role in the pathophysiology of hypertension and vascular disease. Angiotensin-converting enzyme inhibitors (ACEi's) suppress angiotensin II (ANG II) concentrations, whereas angiotensin II type 1 (AT1) receptor blockers (ARBs) block the binding of ANG II to AT1 receptors. ACEi's and ARBs are both effective antihypertensive agents and produce similar risk reductions for stroke, a blood pressure-dependent phenomenon. ACEi's also red...
Source: Canadian Journal of Diabetes - March 28, 2018 Category: Endocrinology Source Type: research

A Discrete Event Simulation Model to Assess the Economic Value of a Hypothetical Pharmacogenomics Test for Statin-Induced Myopathy in Patients Initiating a Statin in Secondary Cardiovascular Prevention
ConclusionWe found that a strategy favoring patients staying on statin therapy is cost effective even if patients maintained on statin are at risk of rhabdomyolysis. Our results are explained by the fact that statins are highly effective in reducing the CV risk in patients at high CV risk, and this benefit largely outweighs the risk of rhabdomyolysis.
Source: Molecular Diagnosis and Therapy - April 12, 2018 Category: Molecular Biology Source Type: research

Androgens and cardiovascular risk: A series of case report in the French and Canadian pharmacovigilance databases.
CONCLUSION: Our study shows a very low report of cardiovascular effects under testosterone, all doubtful. Pending further studies, it seems reasonable to consider the cardiovascular risk of patients who are candidates for hormone therapy for age-related androgen deficiency. LEVEL OF EVIDENCE: 3. PMID: 29650456 [PubMed - as supplied by publisher]
Source: Progres en Urologie - April 15, 2018 Category: Urology & Nephrology Tags: Prog Urol Source Type: research

Married people who have had a heart attack are 'more likely to survive another than divorcees'
Married people who have had a heart attack are far more likely to survive a second attack or stroke than divorcees, new Canadian research suggests.
Source: the Mail online | Health - April 18, 2018 Category: Consumer Health News Source Type: news

Married people who have had heart attack 'cope better than divorcees'
Married people who have had a heart attack are far more likely to survive a second attack or stroke than divorcees, new Canadian research suggests.
Source: the Mail online | Health - April 18, 2018 Category: Consumer Health News Source Type: news