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Condition: Heart Attack
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Total 334 results found since Jan 2013.

miR-532-3p-CSF2RA Axis as a Key Regulator of Vulnerable Atherosclerotic Plaque Formation
ConclusionsMacrophagic miR-532-3p-CSF2RA axis dysregulation is a key driver in vulnerable plaque formation.
Source: Canadian Journal of Cardiology - December 29, 2019 Category: Cardiology Source Type: research

Biological agents reduce cardiovascular events in rheumatoid arthritis non-responsive to tumor necrosis factor-inhibitors – a national cohort study
ConclusionsRA TNFi non-responder patients who received second line tocilizumab or abatacept had more benefit on CV events prevention compared with rituximab.
Source: Canadian Journal of Cardiology - January 16, 2020 Category: Cardiology Source Type: research

Predictors of fatal and non-fatal cardiovascular events in ANCA-associated vasculitis: data from the Toronto CanVasc cohort
Conclusions: In this cohort of patients with granulomatosis with polyangiitis and eosinophilic granulomatosis with polyangiitis, both traditional and disease related risk factors were predictive of cardiovascular events. Further prospective studies should elucidate the impact of these and other modifiable risk factors on cardiovascular risk in ANCA-associated vasculitis.
Source: Joint Bone Spine - January 18, 2020 Category: Orthopaedics Source Type: research

Blood Pressure at Six Months after Acute Myocardial Infarction and Outcomes at Two Years: The Perils Associated with Excessively Low Blood Pressures
ConclusionsLow blood pressure achieved with beta-blocker and renin-angiotensin-aldosterone blocker at 6-month was associated with an increased risk of all-cause mortality independently of confounding factors in patients with AMI. This finding suggests that caution should be taken for patients with AMI who use blood pressure-lowering treatments.
Source: Canadian Journal of Cardiology - February 9, 2020 Category: Cardiology Source Type: research

Oral Anticoagulants and Antiplatelet Agents in Atrial Fibrillation Patients with Concomitant Critical Limb Ischemia: A nationwide cohort study
ConclusionsDOAC was associated with a significantly lower risk of composite net-clinical-benefit outcome than either warfarin or APT in AF patients with concomitant CLI. Further prospective study is necessary to validate the findings in the future.
Source: Canadian Journal of Cardiology - February 19, 2020 Category: Cardiology Source Type: research

The Impact of Sex and Gender on Heart-Brain Axis Dysfunction: Current Concepts and Novel Perspectives.
Abstract The Heart-Brain Axis (HBA) recapitulates all the circuits that regulate bidirectional flow of communication between heart and brain. Several mechanisms may underlie the interdependent relationship involving heterogeneous tissues at rest and during specific target organ injury, such as myocardial infarction, heart failure, arrhythmia, stroke, mood disorders or dementia. In-depth translational studies of the HBA dysfunction under single-organ injury should include both male and female animals to develop sex/gender-oriented prevention, diagnosis and treatment strategies. Indeed, sex and gender are determinin...
Source: Canadian Journal of Physiology and Pharmacology - September 30, 2020 Category: Drugs & Pharmacology Authors: Baroni C, Lionetti V Tags: Can J Physiol Pharmacol Source Type: research

Barilla Foundation Brings Health and Climate Together in New Double Pyramid
The Barilla Foundation New Double Pyramid includes seven cultural pyramids including ones for specific regions like South Asia where these rice workers come from. Other cultural regions include Latin America, East Asia, Nordic and Canada, USA, Mediterranean and Africa. Credit: Deepak Kumar / Unsplash By Alison KentishNEW YORK, Apr 12 2021 (IPS) Following an extensive scientific review, the Barilla Center for Food and Nutrition Foundation (BCFN) is preparing to launch a new food systems model which incorporates nutrition and climate. Researchers from the Foundation teamed up with counterparts from the Frederico II Univers...
Source: IPS Inter Press Service - Health - April 12, 2021 Category: International Medicine & Public Health Authors: Alison Kentish Tags: Climate Change Economy & Trade Environment Featured Food & Agriculture Food Security and Nutrition Food Sustainability Global Headlines Health Humanitarian Emergencies Natural Resources TerraViva United Nations Barilla Center for Source Type: news

The Cost Implications of Dabigatran in Patients with Myocardial Injury After Non-Cardiac Surgery
ConclusionDabigatran 110  mg twice daily was cost neutral for patients in the MANAGE trial. Our cost findings support the use of dabigatran 110 mg twice daily in patients with MINS.Trial RegistrationClinicalTrials.gov identifier number NCT01661101.
Source: American Journal of Cardiovascular Drugs - July 26, 2021 Category: Cardiology Source Type: research

Diabetes prevalence and complication rates: In individual First Nations communities in the Sioux Lookout region of Ontario
CONCLUSION: This study demonstrates the possibility of reporting diabetes prevalence by individual First Nations reserve communities. Complication rates can be reported by individual community, but estimates are more useful for comparison if the smallest communities are grouped together. Such studies could be replicated across Canada to promote local use of these data for resource planning and monitoring long-term progress of diabetes programs and services.PMID:34385208 | DOI:10.46747/cfp.6708601
Source: Canadian Family Physician Medecin de Famille Canadien - August 13, 2021 Category: Primary Care Authors: Benjamin T B Chan Sumeet K Sodhi Graham C Mecredy Terri Farrell Janet Gordon Source Type: research