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A right convergence area of the prefrontal lobe is involved in the improvement of semantic fluency in patients with post-stroke aphasia
CONCLUSION: The improvement of semantic fluency in subacute PSA patients may require the participation of the right convergence area of the prefrontal lobe.PMID:37651207 | DOI:10.1080/10749357.2023.2253632
Source: Topics in Stroke Rehabilitation - August 31, 2023 Category: Neurology Authors: Tao Feng Chao Zhang Siwei Xu Lingmin Wang Kai Xu Zhiyuan Xie Jie Xiang Weiwei Chen Source Type: research

Progress in the clinical application of constraint-induced therapy following stroke since 2014
Stroke is a group of cerebrovascular diseases with high prevalence and mortality rate. Stroke can induce many impairments, including motor and cognitive dysfunction, aphasia/dysarthria, dysphagia, and mood disorders, which may reduce the quality of life among the patients. Constraint-induced therapy has been proven to be an effective treatment method for stroke rehabilitation. It has been widely used in the recovery of limb motor dysfunction, aphasia, and other impairment like unilateral neglect after stroke. In recent years, constraint-induced therapy can also combine with telehealth and home rehabilitation. In addition, ...
Source: Frontiers in Neurology - May 19, 2023 Category: Neurology Source Type: research

Case report: Young-onset large vessel ischemic stroke due to hyperhomocysteinemia associated with the C677T polymorphism on 5,10-methylenetetrahydrofolate reductase and multi-vitamin deficiency
Hyperhomocysteinemia is an important risk factor for cerebral infarction. Herein, we report on a 30-year-old man previously diagnosed with epilepsy who presented with right hemiplegia and total aphasia. Magnetic resonance imaging showed a fronto-temporal ischemic lesion due to occlusion of the left middle cerebral artery. Clinical testing and imaging demonstrated that he had hyperhomocysteinemia induced by multiple factors including the C677T polymorphism on 5.10-methylenetetrahydrofolate reductase (MTHFR), and multiple vitamin deficiencies. The C677T polymorphism on MTHFR is closely related to hyperhomocysteinemia and fol...
Source: Frontiers in Neurology - May 18, 2023 Category: Neurology Source Type: research

Abnormal resting-state function within language network and its improvement among post-stroke aphasia
Behav Brain Res. 2023 Feb 11:114344. doi: 10.1016/j.bbr.2023.114344. Online ahead of print.ABSTRACTSeveral studies with resting-state magnetic resonance imaging (rs-fMRI) have examined functional impairments and plasticity within language network in patients with post-stroke aphasia (PSA). However, there is still ubiquitous inconsistency across these studies, partly due to restricted to very small sample size and the absence of validation with follow-up data. In the current study, we aimed at providing relatively strong evidence to support functional impairments and its reorganization in PSA. Here, the amplitude of low fre...
Source: Behavioural Brain Research - February 13, 2023 Category: Neurology Authors: Xiaohui Xie Panpan Hu Yanghua Tian Bensheng Qiu Kai Wang Tongjian Bai Source Type: research

White matter microstructural integrity pre- and post-treatment in individuals with chronic post-stroke aphasia
This study also found preliminary evidence of left inferior longitudinal fasciculus microstructural changes following treatment.PMID:35921727 | DOI:10.1016/j.bandl.2022.105163
Source: Brain and Language - August 3, 2022 Category: Neurology Authors: Emily J Braun Anne Billot Erin L Meier Yue Pan Todd B Parrish Ajay S Kurani Swathi Kiran Source Type: research

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